Institut Esthederm E.V.E. "Essential Vital Elements" Serum Source
Something wrong? Edit here- Anti-oxidation
- Anti-aging
- Moisturizing
- lactic acid
- niacinamide
- ascorbic acid
- +25 more
FULFILLED

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Formula review
Promise
What does the product description say?WIMJ summary
This product contains adenosine, alanyl glutamine, aspartic acid, folic acid, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
MEDIUM
| |||
MEDIUM
| |||
MEDIUM
|
Promise
What does the product description say?WIMJ summary
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": alanine, alanyl glutamine.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
HIGH | |||
HIGH |
WIMJ summary
This product contains antioxidants (thioctic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
LOW
| |||
LOW
|
Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
lactic acid | ||
sodium citrate | ||
sodium lauroyl glutamate |
Ingredients by volume
Ingredient | Estimated concentration |
---|---|
Plain old water
| 45% - 55% |
Used to stabilize the product formulation and can help absorb oil
| 5.3% - 6.5% |
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
| 4.4% - 5.4% |
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Questions
Skincare resources
Scientific Sources
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- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Epidermal and dermal effects of topical lactic acid
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Ecofriendly surfactant is allergen of the year
- TOPICAL COMPOSITIONS CONTAINING WHEY PROTEINS
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Safety Assessment of α-Amino Acids as Used in Cosmetics
- Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases
- Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus
- Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trial
- Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells
- Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proof
- In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmness
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trial
- Amended Safety Assessment of Sodium Sulfate as Used in Cosmetics
- Folic acid and creatine improve the firmness of human skin in vivo
- Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts
- Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivo
- Dexapanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Safety Assessment of Zinc Salts as Used in Cosmetics
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Efficacy and Safety of White Willow Bark (Salix alba) Extract