
“Laboratory tests confirm that it can reduce the length and depth of wrinkles, can soften wrinkles.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains hydroxypinacolone retinoate.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: hydroxypinacolone retinoate.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.
This product can help reduce breakouts and clogged pores because it contains the following ingredient: hydroxypinacolone retinoate. This ingredient is used for treating acne and can have a noticeable effect.


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A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneUsed to dissolve other ingredients in a product and can enhance their ability to penetrate the skin
More about Dimethyl isosorbideA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
More about Hydroxypinacolone retinoateA preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolUsed to create a thicker product consistency
More about Sodium acrylates copolymerA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateUsed to create a thicker product consistency
More about Xanthan gumUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
More about LecithinWater, Caprylic/capric triglyceride, Glycerin, Squalane, Dimethyl isosorbide, Hydroxypinacolone retinoate, Phenoxyethanol, Sodium acrylates copolymer, Tocopheryl acetate, Xanthan gum, Lecithin, Disodium edta, Ethylhexylglycerin
Retailers ranked by price — lowest first.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Helia-DCell Concept Granactive Retionid SerumYOUR PRODUCT | Lancer SkincareYounger Pure Youth Serum with MIMIXYL | BeautyBioThe Nightly Retinol Repair Serum | IOPEExpert Retinol RX™ 2% Reti-Jection Serum for Wrinkles | |
|---|---|---|---|---|
| Match | — | 93% | 93% | 93% |
| Price | — | — | — | $54.74 |
| Shared key ingredients | — | 3 of 4 | 3 of 4 | 3 of 4 |
| Key difference | — | Glycolic Acid | Tetrahexyldecyl Ascorbate | Niacinamide |
| Irritancy | Medium | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Boost Lab Retinol Night Renewal SerumQ+A Retinol 0.2% Serum
"Helia-D - Cell Concept Granactive Retionid Serum" is effective for: Anti-aging, Evens skin tone and Anti-blemish
This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Every concentration estimate and effectiveness label is anchored to one of these 5 studies and safety reviews.
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