Dr. Loretta Anti-Aging Repair Moisturizer

Dr. Loretta Anti-Aging Repair Moisturizer

Efficacy83/100IrritancyMedium
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Works for

3 of 3 advertised claims delivered

Moisturizing
Tetrapeptide-21, Alanine + 9 more
Strong evidence
What the product description says
“Anti-Aging Repair Moisturizer”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: tetrapeptide-21

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.1–0.3%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~5.5–8.2%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.9–4.3%
Polyglyceryl-2 dipolyhydroxystearateKey activeEffect: HighHelps to soften the upper layer of the skin~0.3–0.75%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.05–0.3%
Tetrapeptide-21HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
ProlineKey activeEffect: Medium~0.1–0.45%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.3–5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.15–0.6%
C13-14 isoparaffin· EmollientEffect: LowHelps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency~0.85–1.25%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.5–1.2%
Anti-aging
Serine, Tetrapeptide-21
Moderate evidence
What the product description says
“Anti-Aging Repair Moisturizer”
From product name

This product contains serine, tetrapeptide-21. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.05–0.3%
Tetrapeptide-21Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Evens skin tone
Dimethylmethoxy chromanyl palmitate, Alanine
Moderate evidence
What the product description says
“Formulated for morning and night use, this anti-aging face moisturizer helps correct common skin concerns-fine lines, uneven skin tone, redness and dryness.”
Source: Dermstore

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: alanine, dimethylmethoxy chromanyl palmitate.

Dimethylmethoxy chromanyl palmitateKey activeEffect: MediumAn oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real life~0.15–0.55%
AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.1–0.3%
Anti-oxidation
Not advertised by the brand · Dimethylmethoxy chromanol, Pelargonium graveolens flower oil + 1 more
Strong evidence

This product contains antioxidants (dimethylmethoxy chromanol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Dimethylmethoxy chromanolKey activeEffect: HighCan help neutralize free radicals in skin~0.1–0.4%
Pelargonium graveolens flower oilEffect: LowAn essential oil. Can be irritating. Can become an allergen with oxidation~0.1–0.5%
Anthemis nobilis flower oilEffect: Low, below effective doseAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin~0.1–0.45%

Can it cause trouble?

Irritancy
2 strong irritants: Pelargonium graveolens flower oil, Lavandula angustifolia oil
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Anthemis nobilis flower oilAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skinHigh~0.1–0.45%est.
Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.1–0.5%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.1–0.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~5.5–8.2%est.
PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~2.1–3.1%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~1.7–2.5%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~1.2–1.8%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–1.2%est.
CarrageenanHelps thicken the product formula and create a nice product formulationMedium~0.45–1%est.
Lauryl glucosideHelps oil and water mix togetherMedium~0.4–1%est.
EthylhexylglycerinA preservativeMedium~0.2–0.75%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.2–0.75%est.
Laureth-7Helps oil and water mix togetherMedium~0.2–0.75%est.
Dimethylmethoxy chromanyl palmitateAn oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real lifeMedium~0.15–0.55%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
CarrageenanHelps thicken the product formula and create a nice product formulation3/5~0.45–1%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.3–5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~5.5–8.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Simmondsia chinensis (jojoba) seed oil, glycerin
Not recognized
Cetearyl alcohol~3.3–5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Dimethicone~2.9–4.3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Polyacrylamide~2.1–3.1%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Cetearyl glucoside~1.7–2.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Polysorbate 20~1.4–2.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Potassium cetyl phosphate~1.2–1.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
C13-14 isoparaffin~0.85–1.25%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Caprylyl glycol~0.5–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Carrageenan~0.45–1%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5

Helps thicken the product formula and create a nice product formulation

More about Carrageenan
Lauryl glucoside~0.4–1%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Lauryl glucoside
Polyglyceryl-2 dipolyhydroxystearate~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin

More about Polyglyceryl-2 dipolyhydroxystearate
Xanthan gum~0.2–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ethylhexylglycerin~0.2–0.75%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hexylene glycol~0.2–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Laureth-7~0.2–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Butylene glycol~0.15–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Pseudoalteromonas ferment extract~0.15–0.55%
Formula
Dimethylmethoxy chromanyl palmitate~0.15–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin tone

An oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real life

More about Dimethylmethoxy chromanyl palmitate
Anthemis nobilis flower oil~0.1–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin

More about Anthemis nobilis flower oil
Pelargonium graveolens flower oil~0.1–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil
Lavandula angustifolia oil~0.1–0.45%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Dimethylmethoxy chromanol~0.1–0.4%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin

More about Dimethylmethoxy chromanol
Proline~0.1–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Alanine~0.1–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Serine~0.05–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Sodium phosphate~0.05–0.25%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Sodium phosphate
Tetrapeptide-21~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tetrapeptide-21
Sodium hydroxide~0.05–0.15%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ingredient list view

Water, Caprylic/capric triglyceride, Unknown, Cetearyl alcohol, Dimethicone, Polyacrylamide, Cetearyl glucoside, Polysorbate 20, Potassium cetyl phosphate, Phenoxyethanol, C13-14 isoparaffin, Caprylyl glycol, Carrageenan, Lauryl glucoside, Polyglyceryl-2 dipolyhydroxystearate, Xanthan gum, Ethylhexylglycerin, Hexylene glycol, Laureth-7, Butylene glycol, Pseudoalteromonas ferment extract, Dimethylmethoxy chromanyl palmitate, Anthemis nobilis flower oil, Pelargonium graveolens flower oil, Lavandula angustifolia oil, Dimethylmethoxy chromanol, Proline, Alanine, Serine, Sodium phosphate, Tetrapeptide-21, Sodium hydroxide

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 10/29/2026 09:00 GMT
$62.92
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Dr Loretta
$70.00
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Dermstore
$70.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Dr. LorettaAnti-Aging Repair MoisturizerYOUR PRODUCTAlgenistRegenerative Anti-Ageing MoisturiserJack BlackDry Erase Ultra-Calming Face CreamDr. Zenovia SkincarePeptide and Ceramide Repairing Moisturiser
Match—55%53%53%
Price$62.92$85.74+$22.82$32.00−$30.92—
Shared key ingredients—3 of 83 of 83 of 8
Key difference—ErgothioneinePanthenolBakuchiol
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"Dr. Loretta - Anti-Aging Repair Moisturizer" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (alanine, butylene glycol and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, cetearyl alcohol, c13-14 isoparaffin and caprylyl glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moisturizer also contains Peptides (tetrapeptide-21 0.05% - 0.20%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Dr. Loretta" is cruelty free and so is its parent company.

Price

The product retails for 70.00$ in the United States.

For a detailed price comparison: click here.

Dr. Loretta Anti-Aging Repair Moisturizer
Dr. LorettaAnti-Aging Repair Moisturizer

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.