Replenix Restorative Nighttime Bio-Therapy
Works for
2 of 2 advertised claims delivered
Moisturizing19 ingredients credited for this claimStrong support
“Replenix Restorative Nighttime Bio-Therapy combats skin dryness and enhances barrier function overnight.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, ceramide ap, ceramide eop, ceramide np, phytosphingosine, tetrapeptide-21
Anti-aging2 ingredients credited for this claimModerate support
“Reservatol, green tea polyphenols and caffeine offer antioxidant benefits to nourish and protect against environmental stressors, promoting healthy, youthful skin.”
This product contains resveratrol, tetrapeptide-21. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Anti-oxidationNot advertised by the brand · 3 ingredients credited for this claimStrong support
This product contains antioxidants (resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy1 strong irritant: ParfumMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
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Water~45–55%
Cyclopentasiloxane~6.6–8.1%
- Irritation risk
- Low
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
More about CyclopentasiloxaneSodium pca~4.2–5.1%
- Irritation risk
- Low
Naturally present in skin and helps to attract water to its upper layer
More about Sodium pcaGlycerin~3.1–3.8%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPolysorbate 60~2.3–2.8%
Cetearyl alcohol~2–2.4%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholYucca glauca root extract~1.6–2%
- Irritation risk
- Low
Dimethicone~1.5–1.9%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeCetearyl glucoside~1.2–1.4%
- Irritation risk
- Medium
Helps water and oil in the product mix well together and improves product texture
More about Cetearyl glucosidePolyacrylamide~1–1.2%
- Irritation risk
- Medium
Used to improve product texture and help oil and water mix together
More about PolyacrylamideC13-14 isoparaffin~0.75–1.1%
- Irritation risk
- Low
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
More about C13-14 isoparaffinLaureth-7~0.6–0.9%
Ceramide np~0.55–0.85%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npCeramide ap~0.45–0.7%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide apCeramide eop~0.45–0.7%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide eopSodium hyaluronate~0.45–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronatePhytosphingosine~0.5–0.7%
- Irritation risk
- Low
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
More about PhytosphingosineCholesterol~0.45–0.7%
- Irritation risk
- Low
An emollient that is naturally found in skin
More about CholesterolSodium lauroyl lactylate~0.35–0.6%
- Irritation risk
- Medium
Helps water and oil mix together
More about Sodium lauroyl lactylateCamellia sinensis polyphenols~0.35–0.65%
- Irritation risk
- Low
Malus domestica fruit cell culture extract~0.25–0.5%
- Irritation risk
- Low
Squalane~0.3–0.6%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneCeramide 2~0.3–0.5%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide 2Tetrapeptide-21~0.25–0.45%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Tetrapeptide-21Resveratrol~0.25–0.5%
- Irritation risk
- Medium
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
More about ResveratrolBisabolol~0.2–0.4%
- Irritation risk
- Low
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
More about BisabololCaffeine~0.25–0.45%
- Irritation risk
- Medium
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
More about CaffeineLecithin~0.25–0.5%
- Irritation risk
- Low
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
More about LecithinGlyceryl stearate~0.25–0.5%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearatePeg-100 stearate~0.3–0.6%
- Irritation risk
- Low
Helps oil and water mix togehter and creates a nice product texture
More about Peg-100 stearateDimethicone crosspolymer~0.2–0.35%
- Irritation risk
- Low
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
More about Dimethicone crosspolymerCarbomer~0.2–0.35%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerXanthan gum~0.2–0.35%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumPhenoxyethanol~0.15–0.25%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolSorbic acid~0.1–0.25%
Caprylyl glycol~0.15–0.25%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolDisodium edta~0.05–0.1%
Parfum~0.05–0.1%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumIngredient list view
Water, Cyclopentasiloxane, Sodium pca, Glycerin, Unknown, Polysorbate 60, Cetearyl alcohol, Yucca glauca root extract, Dimethicone, Cetearyl glucoside, Polyacrylamide, C13-14 isoparaffin, Laureth-7, Ceramide np, Ceramide ap, Ceramide eop, Sodium hyaluronate, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Camellia sinensis polyphenols, Malus domestica fruit cell culture extract, Squalane, Ceramide 2, Tetrapeptide-21, Resveratrol, Bisabolol, Caffeine, Lecithin, Glyceryl stearate, Peg-100 stearate, Dimethicone crosspolymer, Carbomer, Xanthan gum, Phenoxyethanol, Sorbic acid, Caprylyl glycol, Disodium edta, Parfum
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| ReplenixRestorative Nighttime Bio-TherapyYOUR PRODUCT | Dr. Zenovia SkincarePeptide + Ceramide Repairing Moisturizer | Simply PureSuperdrug Simply Pure Hydrating Serum | Key SoulcareSKIN TRANSFORMATION CREAM FRAGRANCE FREE | |
|---|---|---|---|---|
| Match | — | 68% | 53% | 52% |
| Price | $76.50 | $34.00−$42.50 | $4.63−$71.87 | $34.00−$42.50 |
| Shared key ingredients | — | 16 of 16 | 8 of 16 | 9 of 16 |
| Key difference | — | Bakuchiol | Lactic Acid | Niacinamide |
| Irritancy | Medium | Medium | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
"Replenix - Restorative Nighttime Bio-Therapy" is a well-rounded moisturizing product. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Glycerin, sodium hyaluronate, sodium pca and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide 2, ceramide eop, ceramide np, phytosphingosine and cholesterol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- As a plus, this moisturizer also contains ceramides (ceramide np 0.55% - 0.85%, ceramide 2 0.30% - 0.50%, phytosphingosine 0.50% - 0.70%, ceramide eop 0.45% - 0.70% and ceramide ap 0.45% - 0.70%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (tetrapeptide-21 0.25% - 0.45%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 76.50$ up to 95.00$ in the United States and from 86.40CA$ up to 186.83CA$ in Canada.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.
- 1
- 2
- 3Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 4Safety Assessment of Isoparaffins as Used in Cosmeticsjournals.sagepub.com
- 5
- 6
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