Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Anti-oxidation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"Replenix - Restorative Nighttime Bio-Therapy" is a well-rounded moisturizing product. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Glycerin, sodium hyaluronate, sodium pca and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide 2, ceramide eop, ceramide np, phytosphingosine and cholesterol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- As a plus, this moisturizer also contains ceramides (ceramide np 0.55% - 0.85%, ceramide 2 0.30% - 0.50%, phytosphingosine 0.50% - 0.70%, ceramide eop 0.45% - 0.70% and ceramide ap 0.45% - 0.70%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (tetrapeptide-21 0.25% - 0.45%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 76.50$ up to 95.00$ in the United States and from 86.40CA$ up to 186.83CA$ in Canada.
For a detailed price comparison: click here.
Works for
Anti-oxidation
This product contains antioxidants (resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
Moisturizing
What does the product description say?
Replenix Restorative Nighttime Bio-Therapy combats skin dryness and enhances barrier function overnight.
Source: SkincareRX
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, ceramide ap, ceramide eop, ceramide np, phytosphingosine, tetrapeptide-21
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Naturally present in skin and helps to attract water to its upper layer
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An emollient that is naturally found in skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Helps preserve products and creates a nice product texture
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Anti-aging
What does the product description say?
Reservatol, green tea polyphenols and caffeine offer antioxidant benefits to nourish and protect against environmental stressors, promoting healthy, youthful skin.
Source: Dermstore
This product contains resveratrol, tetrapeptide-21. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging |
Total Promises Fulfilled score: 87/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Replenix Restorative Nighttime Bio-Therapy | Current | $86.40 | |
 Dr. Zenovia Skincare Peptide + Ceramide Repairing Moisturizer | 68% | - | |
Simply Pure Superdrug Simply Pure Hydrating Serum | 53% | $3.49 | |
Key Soulcare SKIN TRANSFORMATION CREAM FRAGRANCE FREE | 52% | $34.00 | |
 Dr Dennis Gross Hyaluronic Marine™ Hydration Booster Deluxe | 51% | - | |
 Alpha-H Vitamin E Serum with Macadamia | 51% | $65.60 |
Key Actives
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An emollient that is naturally found in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
Naturally present in skin and helps to attract water to its upper layer
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Helps water and oil in the product mix well together and improves product texture
Used to improve product texture and help oil and water mix together
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
Helps preserve products and creates a nice product texture
Comedogenic ingredients
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
All ingredients
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Naturally present in skin and helps to attract water to its upper layer
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Helps water and oil in the product mix well together and improves product texture
Used to improve product texture and help oil and water mix together
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
A preservative. It helps prevent bacterial growth in cosmetic products
Helps preserve products and creates a nice product texture
An aromatic blend of unspecified and possibly irritating ingredients
Ingredient list view
Water, Cyclopentasiloxane, Sodium pca, Glycerin, Unknown, Polysorbate 60, Cetearyl alcohol, Yucca glauca root extract, Dimethicone, Cetearyl glucoside, Polyacrylamide, C13-14 isoparaffin, Laureth-7, Ceramide np, Ceramide ap, Ceramide eop, Sodium hyaluronate, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Camellia sinensis polyphenols, Malus domestica fruit cell culture extract, Squalane, Ceramide 2, Tetrapeptide-21, Resveratrol, Bisabolol, Caffeine, Lecithin, Glyceryl stearate, Peg-100 stearate, Dimethicone crosspolymer, Carbomer, Xanthan gum, Phenoxyethanol, Sorbic acid, Caprylyl glycol, Disodium edta, Parfum
- Glycerol and the skin: holistic approach to its origin and functions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Isoparaffins as Used in Cosmetics
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Skin permeation and antioxidant efficacy of topically applied resveratrol
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
- Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
- Resveratrol as a Multifunctional Topical Hypopigmenting Agent
- Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation
- Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skin
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation