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Dermedicine Vitamin C 6000 Ultimate Dark Spot Corrector Serum
Dermedicine

Dermedicine Vitamin C 6000 Ultimate Dark Spot Corrector Serum

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Retinol, Nonapeptide-1 + 3 more
Works well
What the product description says
“Tackle the appearance of tough dark spots, pigmentation and keep your skin looking smooth, even, youthful and bright using our potent topical anti aging Vitamin-C with Retinol serum to help fade the appearance of fine lines and wrinkles while balancing out blotchiness that becomes more apparent as we age.”
Source: Dermdeicine

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: nonapeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.75%
Nonapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.6–2.3%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~3–4.4%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.35%
Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.4–0.95%
Evens skin tone
Retinol, Alpha-arbutin + 2 more
Works well
What the product description says
“Vitamin C 6000 Ultimate Dark Spot Corrector Serum”
From product name

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains alpha-arbutin. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.75%
Alpha-arbutinKey activeEffect: HighMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin~1.3–2%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.35%
Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.4–0.95%
Moisturizing
Side benefit · Nonapeptide-1, Chondrus crispus + 2 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: nonapeptide-1

Nonapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.6–2.3%
Chondrus crispusKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~22–33%
Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~7.7–11.6%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~3–4.4%
Anti-oxidation
Side benefit · Retinol, Ascorbic acid
Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.75%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.35%
Anti-blemish
Side benefit · Retinol, Retinyl palmitate
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.75%
Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.4–0.95%
Exfoliation
Side benefit · Retinol, Retinyl palmitate
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.75%
Retinyl palmitateEffect: Low, below effective doseThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.4–0.95%

Can it cause trouble?

Irritancy
2 strong irritants: Retinyl palmitate, Retinol
Medium risk
We flagged 5 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.9–1.35%est.
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.4–0.95%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.2–0.75%est.
Alpha-arbutinMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutinMedium~1.3–2%est.
EthylhexylglycerinA preservativeMedium~0.05–0.3%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Chondrus crispusRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~22–33%est.
Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~7.7–11.6%est.
Alternatives
The closest match we found
Pro-Heal Serum Advance Plus
iS Clinical Pro-Heal Serum Advance Plus
Closest match69% match
$127.19
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Chondrus crispus~22–33%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus
Chondrus crispus extract~7.7–11.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract
Water~4.6–6.9%
Formula
Irritation risk
Low

Plain old water

More about Water
Hyaluronic acid~3–4.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Rumex occidentalis extract~2–3.1%
Formula
Irritation risk
Low
More about Rumex occidentalis extract
Nonapeptide-1~1.6–2.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nonapeptide-1
Alpha-arbutin~1.3–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin

More about Alpha-arbutin
Ascorbic acid~0.9–1.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-agingEvens skin tone

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Retinyl palmitate~0.4–0.95%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-agingEvens skin toneExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Retinol~0.2–0.75%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
ExfoliationAnti-oxidationAnti-agingEvens skin toneAnti-blemishMattifying

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Phenoxyethanol~0.1–0.45%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Chondrus crispus, Chondrus crispus extract, Water, Hyaluronic acid, Rumex occidentalis extract, Nonapeptide-1, Alpha-arbutin, Ascorbic acid, Retinyl palmitate, Retinol, Phenoxyethanol, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DermedicineVitamin C 6000 Ultimate Dark Spot Corrector SerumYOUR PRODUCTiS ClinicalPro-Heal Serum Advance PluspureclinicaTriple Strength Vitamin C, E & Ferulic Acid SerumPixiVitamin-C Serum
Match—69%68%60%
Price—$127.19$29.99$24.00
Shared key ingredients—2 of 82 of 82 of 8
Key difference—ArbutinSalicylic AcidFerulic Acid
Irritancy Medium Medium Medium High
Drying alcohol— Contains drying alcohol ——
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Product summary

"Dermedicine - Vitamin C 6000 Ultimate Dark Spot Corrector Serum" is effective for: Moisturizing, Anti-aging, Evens skin tone, Anti-blemish and Exfoliation

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.90% - 1.35%) it cannot have a noticeable benefit for the skin.
  • This product contains an effective form of Retinoids (vitamin A): retinol 0.20% - 0.75%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
  • Peptides (nonapeptide-1 1.60% - 2.30%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Humectants (hyaluronic acid 3.00% - 4.40%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 95.00$ in the United States.

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.

  1. 1
    Seaweeds as Source of Bioactive Substances and Skin Care Therapy—Cosmeceuticals, Algotheraphy, and Thalassotherapymdpi.com
  2. 2
    Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
  3. 3
    Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
  4. 4
    Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
  5. 5
    Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
  6. 6
    A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
Dermedicine Vitamin C 6000 Ultimate Dark Spot Corrector Serum
DermedicineVitamin C 6000 Ultimate Dark Spot Corrector Serum
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