Works for
MoisturizingCeramide np, Caprylic/capric triglyceride + 6 moreWorks well
“A concentrated blend of Retinol, Vitamin C and Collagen helps skin feel stronger, appear firmer and look plumper.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed collagen.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, hydrolyzed collagen.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np
ExfoliationSide benefit · RetinolWorks well
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Anti-blemishSide benefit · Retinol, NiacinamideWorks well
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
Anti-oxidationSide benefit · Ascorbic acid, RetinolWorks well
This product contains antioxidants (ascorbic acid, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Evens skin toneSide benefit the brand mentions · Ascorbic acid, Retinol + 1 moreWorks well
“BRIGHTER AND MORE EVEN-LOOKING COMPLEXION.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: ascorbic acid, retinol.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Anti-agingSide benefit the brand mentions · Ascorbic acid, Retinol + 1 moreWorks well
“Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide work together to promote skin that appears more youthful-looking.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains ascorbic acid, retinol.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Can it cause trouble?
Irritancy1 strong irritant: RetinolMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Propylene glycol~23–34%
- Irritation risk
- High
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
More about Propylene glycolAscorbic acid~6.1–9.1%
- Irritation risk
- High
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
More about Ascorbic acidRetinol~4.6–6.9%
- Irritation risk
- High
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
More about RetinolCaprylic/capric triglyceride~3.7–5.5%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideGlycerin~2.5–3.8%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPolysorbate 20~1.8–2.7%
Cetyl palmitate~1.6–2.4%
- Irritation risk
- Low
An emollient that helps soften the skin and is used to improve product texture and stability
More about Cetyl palmitateLaureth-23~1.2–1.7%
- Irritation risk
- Medium
- Comedogenicity
- 2/5
Helps oil and water mix together
More about Laureth-23Trideceth-6 phosphate~0.6–1.4%
- Irritation risk
- Medium
Helps oil and water mix together
More about Trideceth-6 phosphateSodium hyaluronate~0.5–1.2%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateHydrolyzed collagen~0.85–1.25%
- Irritation risk
- Low
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
More about Hydrolyzed collagenPhenoxyethanol~0.2–0.75%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolTriethanolamine~0.15–0.55%
- Irritation risk
- Medium
Used to adjust pH of the product and can help improve the product's smell
More about TriethanolamineCeramide np~0.15–0.65%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npNiacinamide~0.05–0.25%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideIngredient list view
Propylene glycol, Ascorbic acid, Retinol, Caprylic/capric triglyceride, Glycerin, Polysorbate 20, Cetyl palmitate, Laureth-23, Trideceth-6 phosphate, Sodium hyaluronate, Hydrolyzed collagen, Phenoxyethanol, Triethanolamine, Ceramide np, Niacinamide
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Dermedicine5-in-1 Super Charged SerumYOUR PRODUCT | iS ClinicalPro-Heal Serum Advance Plus | PixiVitamin-C Serum | Pura d'or20% Vitamin C Serum | |
|---|---|---|---|---|
| Match | — | 76% | 71% | 69% |
| Price | — | $125.19 | $22.92 | $15.19 |
| Shared key ingredients | — | 3 of 7 | 5 of 7 | 3 of 7 |
| Key difference | — | Arbutin | Ferulic Acid | Ferulic Acid |
| Irritancy | Medium | Medium | High | Medium |
| Drying alcohol | — | Contains drying alcohol | — | — |
| View product | Shop | Shop | Shop |
More alternatives: The Purest Solutions Youth Radiant Renewal Retinol SerumALASTIN Skincare Renewal Retinol
Product summary
"Dermedicine - 5-in-1 Super Charged Serum" is effective for: Exfoliation, Anti-blemish, Anti-aging, Moisturizing and Evens skin tone
Ingredient callouts
- This product also contains Vitamin C (Ascorbic Acid) 6.10% - 9.10% It can be helpful in stimulating collagen production, neutralizing free radicals in skin and improving pigmentation marks. We recommend to use up this product quickly after opening: Ascorbic Acid degrades fast when it gets in contact with air and light. The moment the product turns orange, it is a sign that a significant share of the vitamin C in it is no longer effective.
- This product contains an effective form of Retinoids (vitamin A): retinol 4.60% - 6.90%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Ceramides (ceramide np 0.35% - 0.75%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- Humectants (hydrolyzed collagen 0.95% - 1.40%, sodium hyaluronate 0.55% - 1.30% and glycerin 2.50% - 3.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 65.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 13 studies and safety reviews.
- 1Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
- 2Propylene Glycolpubmed.ncbi.nlm.nih.gov
- 3Skin-sensitizing and irritant properties of propylene glycolonlinelibrary.wiley.com
- 4
- 5Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
- 6
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