PRODUCT REVIEW
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Dermatica Tretinoin 0.1% / Azelaic Acid 15% / Tranexamic Acid 5%
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Product summary
What can the product work for?
Works for
Does not work for
Anti-aging
tretinoin
39% -
58%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Evens skin tone
What does the product description say?
Azelaic acid and Tranexamic acid helps reduce areas of hyperpigmentation, evening out overall skin tone.
tretinoin
39% -
58%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
tranexamic acid
3.9% -
5.9%
Irritation risk:
Concentration: Effectiveness: HIGH
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
azelaic acid
5.7% -
8.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
Anti-blemish
tretinoin
39% -
58%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
azelaic acid
5.7% -
8.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
phytosphingosine
0.1% -
0.45%
Irritation risk:
Concentration: Effectiveness:
LOW
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Moisturizing
dimethicone
0.45% -
1.1%
Irritation risk:
Concentration: Effectiveness: HIGH
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
ceramide ap
0.1% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
ceramide eop
0.15% -
0.6%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
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Anti-oxidation
tretinoin
39% -
58%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
azelaic acid
5.7% -
8.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
tocopheryl acetate
0.15% -
0.55%
Irritation risk:
Concentration: Insufficient!
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Exfoliation
What does the product description say?
Tretinoin works by increasing the skin cell turnover rate, which helps exfoliate the skin and improve the signs of photodamage.
azelaic acid
5.7% -
8.5%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Anti-aging | |
Evens skin tone | |
Exfoliation |
Total Promises Fulfilled score:
83/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
tretinoin
39% -
58%
Irritation risk:
Works for:
Anti-oxidation,
Mattifying,
Evens skin tone,
Anti-aging,
Anti-blemish
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
propylene glycol
2.2% -
3.3%
Irritation risk:
Works for:
Moisturizing
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
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Comodogenic ingredients
No comodogenic ingredients detected
User reviews (0)
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Price | ||||||||||||
WIMJ similarity score |
56%
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69%
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63%
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62%
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58%
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57%
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57%
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56%
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56%
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56%
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55%
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Key ingredients |
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Other: | Common:
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Other:
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Irritancy | IRRITANCY
MEDIUM
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
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Potential Irritants |
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All ingredients |
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Ingredients & concentrations
All ingredients
Key Actives
tretinoin
39% -
58%
Irritation risk:
Works for:
Anti-oxidation,
Mattifying,
Evens skin tone,
Anti-aging,
Anti-blemish
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
azelaic acid
5.7% -
8.5%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-oxidation,
Exfoliation
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
Show more
Potential irritants
tretinoin
39% -
58%
Irritation risk:
Works for:
Anti-oxidation,
Mattifying,
Evens skin tone,
Anti-aging,
Anti-blemish
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
propylene glycol
2.2% -
3.3%
Irritation risk:
Works for:
Moisturizing
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
tretinoin
39% -
58%
Irritation risk:
Works for:
Anti-oxidation,
Mattifying,
Evens skin tone,
Anti-aging,
Anti-blemish
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
azelaic acid
5.7% -
8.5%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-oxidation,
Exfoliation
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
tranexamic acid
3.9% -
5.9%
Irritation risk:
Works for:
Moisturizing,
Evens skin tone
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
Show more
Ingredient list view
Tretinoin, Azelaic acid, Tranexamic acid, Water, Propylene glycol, Glycerin, Panthenol, Cetyl alcohol, Glyceryl stearate, Isohexadecane, Isododecane, C13-15 alkane, Dimethicone, Propanediol, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Phenoxyethanol, Tocopheryl acetate, Ceramide ap, Ceramide eop, Ceramide np, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Xanthan gum, Carbomer, Sodium hyaluronate
Sources
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Glycerol and the skin: holistic approach to its origin and functions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Hyaluronic acid: A key molecule in skin aging