Works for:
based on ingredients and %- Anti-blemish
- Evens skin tone
- Anti-aging
- Moisturizing
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"Dermatica - Tretinoin 0.05% / Niacinamide 4% / Clindamycin 1%" is effective for: Anti-blemish, Evens skin tone, Moisturizing and Anti-aging
Ingredient callouts
- A good concentration of Niacinamide (5.10% - 6.30%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- This product contains an effective form of Retinoids (vitamin A): tretinoin 44.00% - 54.00%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Ceramides (phytosphingosine 0.25% - 0.45%, ceramide np 0.25% - 0.50%, ceramide eop 0.30% - 0.55% and ceramide ap 0.30% - 0.55%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- Panthenol (pro-vitamin B5) at about 2.20% - 2.70% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
- Humectants (sodium hyaluronate 0.05% - 0.15%, panthenol 2.20% - 2.70% and glycerin 2.80% - 3.40%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains tretinoin, niacinamide.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Anti-blemish
What does the product description say?
Tretinoin is a retinoid that reduces comedones, papules and pustules, and is suited for long term maintenance therapy.
Source: Dermatica
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, tretinoin. These ingredients is used for treating acne and can have a noticeable effect.
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Anti-oxidation
This product contains antioxidants (tretinoin) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Evens skin tone
What does the product description say?
Niacinamide treats pimples and spots by its antiinflammatory activity, which reduces swelling, redness and tenderness.
Source: Dermatica
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: tretinoin.
In addition, this product contains niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cholesterol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ap, ceramide eop, ceramide np, niacinamide, panthenol, phytosphingosine
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An emollient that is naturally found in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
An emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-blemish |
Total Promises Fulfilled score: 100/100.
Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
User reviews (0)
Averages from community submissions.
No reviews yet for this product.
Be the first to share your experience!
Tried this product?
Help capture what the ingredient list can't—texture, finish, pilling, scent, and more. Answer what you can, skip the rest.
Takes ~30 seconds.
Reviews are shown in aggregate. No personal details.
| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Dermatica Tretinoin 0.05% / Niacinamide 4% / Clindamycin 1% | Current | - | |
Éciat Keep Calm Soothing serum | 75% | - | |
 CeraVe Skin Renewing Super Boost Serum | 73% | $29.99 | |
 Apothaka Skincare Barrier Support Serum | 71% | - | |
 PCA SKIN Hyaluronic Acid Boosting Serum | 69% | $130.00 | |
 TBH Skincare rebound serum | 68% | ≈ $47.82 |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An emollient that is naturally found in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
An emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
Used to create a thicker product consistency and stabilize the product formulation
A preservative. It helps prevent bacterial growth in cosmetic products
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Ingredient list view
Tretinoin, Niacinamide, Unknown, Water, Propylene glycol, Glycerin, Panthenol, Cetyl alcohol, Glyceryl stearate, Isohexadecane, Isododecane, C13-15 alkane, Dimethicone, Propanediol, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Phenoxyethanol, Tocopheryl acetate, Ceramide ap, Ceramide eop, Ceramide np, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Xanthan gum, Carbomer, Sodium hyaluronate
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Glycerol and the skin: holistic approach to its origin and functions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care