What's In My Jar
Derma E Anti-Aging Regenerative Night Cream
Derma E

Derma E Anti-Aging Regenerative Night Cream

Efficacy100/100IrritancyHigh
See all ingredients In 2 routines
Edit

Works for

2 of 2 advertised claims delivered

Anti-aging
3 ingredients credited for this claim
Strong support
What the product description says
“Anti-Aging Regenerative Night Cream”
From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, bakuchiol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: astaxanthin.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.6%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
AstaxanthinKey activeEffect: MediumHelps neutralize free radicals in skin and might help to calm down inflammation~0.35–0.6%
Moisturizing
10 ingredients credited for this claim
Strong support
What the product description says
“Anti-Aging Regenerative Night Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.55–0.8%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~1.2–1.5%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.2–5.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.9–5.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.6–2%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~2.4–3%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1.9–2.3%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.4–2.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.4–1.8%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.6%
Exfoliation
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.6%
Anti-oxidation
Not advertised by the brand · 6 ingredients credited for this claim
Strong support

This product contains antioxidants (astaxanthin, bakuchiol, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.6%
AstaxanthinKey activeEffect: HighHelps neutralize free radicals in skin and might help to calm down inflammation~0.35–0.6%
Pinus pinaster bark extractEffect: LowA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)~0.45–0.65%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.95–1.15%
Anthemis nobilis flower oilEffect: Low, below effective doseAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin~0.2–0.4%
Anti-blemish
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.6%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.6%
Evens skin tone
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains bakuchiol. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: pinus pinaster bark extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.6%
Pinus pinaster bark extractEffect: LowA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)~0.45–0.65%

Can it cause trouble?

Irritancy
8 strong irritants: Lavandula angustifolia oil, Salvia officinalis oil + 6 more — patch-test recommended
High risk
We flagged 18 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.3–0.5%est.
Salvia officinalis oil—High~0.25–0.45%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.25–0.45%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.2–0.4%est.
Mentha viridis leaf oilUsed as a fragrance and can be irritatingHigh~0.2–0.4%est.
Camphor—High~0.25–0.4%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.2–0.4%est.
Anthemis nobilis flower oilAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skinHigh~0.2–0.4%est.
Melaleuca alternifolia leaf oilAn essential oil that can be irritating. Has some anti-bacterial propertiesHigh~0.2–0.4%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.2–5.1%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~1.2–1.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.95–1.15%est.
Potassium sorbateA preservativeMedium~0.3–0.6%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.45–0.65%est.
Pinus pinaster bark extractA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)Medium~0.45–0.65%est.
AstaxanthinHelps neutralize free radicals in skin and might help to calm down inflammationMedium~0.35–0.6%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.35–0.6%est.
EthylhexylglycerinA preservativeMedium~0.1–0.15%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Edit
Cheaper Alternatives
Similar formulations, better price
Retinol Cream 2.5%
Naturium Retinol Cream 2.5%
85% match
$15.99
Gentle Retinol Cream
Good Molecules Gentle Retinol Cream
79% match
$7.97
View all alternatives

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Write a review · ~30s

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.9–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Caprylic/capric triglyceride~4.2–5.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cetyl alcohol~2.4–3%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearic acid~2.4–2.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Glyceryl stearate citrate~1.9–2.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Dimethicone~1.6–2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glyceryl stearate~1.4–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Simmondsia chinensis seed oil~1.2–1.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Tocopheryl acetate~0.95–1.15%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Xanthan gum~0.65–0.95%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Panthenol~0.55–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Potassium sorbate~0.3–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Allantoin~0.4–0.6%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemishReduces irritationReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Cetearyl glucoside~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Pinus pinaster bark extract~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)

More about Pinus pinaster bark extract
Astaxanthin~0.35–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-agingAnti-inflammatory

Helps neutralize free radicals in skin and might help to calm down inflammation

More about Astaxanthin
Bakuchiol~0.35–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-oxidationAnti-agingAnti-inflammatoryAnti-blemish

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Lavandula angustifolia oil~0.3–0.5%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Salvia officinalis oil~0.25–0.45%
Irritant · high
Irritation risk
High
More about Salvia officinalis oil
Limonene~0.25–0.45%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Retinol~0.2–0.4%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
ExfoliationMattifyingAnti-blemishEvens skin toneAnti-agingAnti-oxidation

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Eucalyptol~0.2–0.35%
Formula
Irritation risk
Low
More about Eucalyptol
Copaifera reticulata balsam oil~0.2–0.4%
Formula
Irritation risk
Low
More about Copaifera reticulata balsam oil
Mentha viridis leaf oil~0.2–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha viridis leaf oil
Beta-caryophyllene~0.2–0.35%
Formula
Irritation risk
Low
More about Beta-caryophyllene
Camphor~0.25–0.4%
Irritant · high
Irritation risk
High
More about Camphor
Citral~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
L-alpha-pinene~0.25–0.4%
Formula
Irritation risk
Low
More about L-alpha-pinene
Geranyl acetate~0.2–0.4%
Formula
Irritation risk
Low
More about Geranyl acetate
Anthemis nobilis flower oil~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin

More about Anthemis nobilis flower oil
L-beta-pinene~0.2–0.4%
Formula
Irritation risk
Low
More about L-beta-pinene
Melaleuca alternifolia leaf oil~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Antibacterial

An essential oil that can be irritating. Has some anti-bacterial properties

More about Melaleuca alternifolia leaf oil
Isobornyl acetate~0.2–0.35%
Formula
Irritation risk
Low
More about Isobornyl acetate
Neryl acetate~0.2–0.35%
Formula
Irritation risk
Low
More about Neryl acetate
Menthone~0.15–0.3%
Formula
Irritation risk
Low
More about Menthone
Benzyl acetate~0.15–0.3%
Formula
Irritation risk
Low
More about Benzyl acetate
Citronellal~0.15–0.25%
Formula
Irritation risk
Low
More about Citronellal
Terpineol~0.1–0.2%
Formula
Irritation risk
Low
More about Terpineol
Menthyl acetate~0.15–0.25%
Formula
Irritation risk
Low
More about Menthyl acetate
Phenoxyethanol~0.15–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium hydroxide~0.1–0.15%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ingredient list view

Water, Glycerin, Caprylic/capric triglyceride, Cetyl alcohol, Stearic acid, Glyceryl stearate citrate, Dimethicone, Glyceryl stearate, Simmondsia chinensis seed oil, Tocopheryl acetate, Xanthan gum, Panthenol, Potassium sorbate, Allantoin, Cetearyl glucoside, Pinus pinaster bark extract, Astaxanthin, Bakuchiol, Lavandula angustifolia oil, Salvia officinalis oil, Limonene, Polysorbate 20, Retinol, Eucalyptol, Copaifera reticulata balsam oil, Mentha viridis leaf oil, Beta-caryophyllene, Camphor, Citral, L-alpha-pinene, Geranyl acetate, Anthemis nobilis flower oil, L-beta-pinene, Melaleuca alternifolia leaf oil, Isobornyl acetate, Neryl acetate, Menthone, Benzyl acetate, Citronellal, Terpineol, Menthyl acetate, Phenoxyethanol, Ethylhexylglycerin, Sodium hydroxide

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 10/9/2026 21:11 GMT
$24.95
Buy
Derma E
$29.50
Buy

Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EAnti-Aging Regenerative Night CreamYOUR PRODUCTNaturiumRetinol Cream 2.5%Orion PharmaBella A-vitamin night cream unscentedDr Dennis GrossRetinol + Ferulic Anti Aging Wrinkle Cream
Match—85%81%79%
Price$24.95$15.99−$8.96—$77.00+$52.05
Shared key ingredients—5 of 104 of 105 of 10
Key difference—Retinyl PalmitateDimethiconolLactic Acid
Irritancy High Medium Medium High
Drying alcohol————
View product Shop Shop Shop
  • matches yours
  • differs
  • cheaper
Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

"Derma E - Anti-Aging Regenerative Night Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (panthenol and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Caprylic/capric triglyceride, dimethicone, simmondsia chinensis seed oil, cetyl alcohol and glyceryl stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • this moisturizer contains an effective form of retinoids (vitamin A): retinol 0.20% - 0.40%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
  • This formulation also includes panthenol (pro-vitamin B5) at about 0.55% - 0.80% concentration. In this concentration, panthenol works effectively to improve the skin barrier and reduce inflammation.
  • Bakuchiol in this moisturizer (the concentration is about 0.35% - 0.60%). Helps fight photodamage (wrinkles, elasticity loss and pigmentation) and can reduce clogged pores and blemishes. Bakuchiol is a compound extracted from a plant Babchi. It acts similar to retinoids, but with less irritation risk.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.

Price

The product retails from 27.00$ up to 29.50$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
  5. 5
    Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
  6. 6
    Profile of wound healing process induced by allantoinscielo.br
Derma E Anti-Aging Regenerative Night Cream
Derma EAnti-Aging Regenerative Night Cream
Buy at Derma E$29.50$24.95as of 10/9 21:11 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Derma E$29.50$24.95as of 10/9 21:11 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.