Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Exfoliation
- Evens skin tone
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 0
Key actives
Product Summary
Judging from the ingredient list, "Derma E - Anti-Aging Regenerative Day Cream" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Derma E - Anti-Aging Regenerative Day Cream ticks this box. Humectants in this product (panthenol and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, cetyl alcohol, glyceryl stearate and glyceryl stearate citrate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- Bakuchiol in this moisturizer (the concentration is about 0.40% - 0.60%). Helps fight photodamage (wrinkles, elasticity loss and pigmentation) and can reduce clogged pores and blemishes. Bakuchiol is a compound extracted from a plant Babchi. It acts similar to retinoids, but with less irritation risk.
- This moisturizer contains an effective form of Retinoids (vitamin A): retinol 0.20% - 0.35%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
- An effective concentration of Panthenol (pro-vitamin B5) - about 1.30% - 1.60%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
Irritation risk
This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.
Price
The product retails from 19.64$ up to 29.50$ in the United States, for 34.95A$ in Australia and for 33.00£ in the United Kingdom.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Anti-Aging Regenerative Day Cream
Source: From product name
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, bakuchiol.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: astaxanthin.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps neutralize free radicals in skin and might help to calm down inflammation
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Anti-oxidation
This product contains antioxidants (astaxanthin, bakuchiol, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - pinus pinaster bark extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Helps neutralize free radicals in skin and might help to calm down inflammation
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
In addition, this product contains bakuchiol. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: pinus pinaster bark extract.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Moisturizing
What does the product description say?
Anti-Aging Regenerative Day Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Helps oil and water mix together and works as an emollient
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix together while softening the upper layer of the skin
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Derma E Anti-Aging Regenerative Day Cream | Current | $26.00 | |
Naturium Retinol Complex Cream | 85% | $20.00 | |
 Orion Pharma Bella A-vitamin night cream unscented | 80% | - | |
 Revision Skincare D-E-J Night Face Cream | 78% | $162.50 | |
 Dr Dennis Gross Retinol + Ferulic Anti Aging Wrinkle Cream | 78% | $77.00 | |
Good Molecules Gentle Retinol Cream | 78% | $19.20 |
Key Actives
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Helps neutralize free radicals in skin and might help to calm down inflammation
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Potential irritants
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
An essential oil that can be irritating. Has some anti-bacterial properties
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Helps water and oil in the product mix well together and improves product texture
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Helps neutralize free radicals in skin and might help to calm down inflammation
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Helps oil and water mix together while softening the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Helps water and oil in the product mix well together and improves product texture
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Helps neutralize free radicals in skin and might help to calm down inflammation
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
An essential oil that can be irritating. Has some anti-bacterial properties
A preservative. It helps prevent bacterial growth in cosmetic products
Ingredient list view
Water, Glycerin, Caprylic/capric triglyceride, Stearic acid, Cetyl alcohol, Glyceryl stearate citrate, Glyceryl stearate, Panthenol, Dimethicone, Simmondsia chinensis seed oil, Tocopheryl acetate, Xanthan gum, Cetearyl glucoside, Allantoin, Pinus pinaster bark extract, Sodium hydroxide, Bakuchiol, Astaxanthin, Lavandula angustifolia oil, Salvia officinalis oil, Limonene, Polysorbate 20, Retinol, Eucalyptol, Copaifera reticulata balsam oil, Mentha viridis leaf oil, Beta-caryophyllene, Camphor, Citral, L-alpha-pinene, Geranyl acetate, Anthemis nobilis flower oil, L-beta-pinene, Melaleuca alternifolia leaf oil, Isobornyl acetate, Neryl acetate, Menthone, Benzyl acetate, Citronellal, Terpineol, Menthyl acetate, Phenoxyethanol, Potassium sorbate, Ethylhexylglycerin
- Glycerol and the skin: holistic approach to its origin and functions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Profile of wound healing process induced by allantoin
- Study of nutraceutical, nutricosmetics and cosmeceutical potentials of polyphenolic bark extracts from Canadian forest species
- Bakuchiol in the Management of Acne-affected Skin
- Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageing
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
- Astaxanthin, canthaxanthin and b-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes
- Astaxanthin attenuates the UVA-induced up-regulation of matrixmetalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts
- Protective Effects of Topical Application of a Poorly Soluble Antioxidant Astaxanthin Liposomal Formulation on Ultraviolet-Induced Skin Damage
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Safety Assessment of Anthemis nobilis– Derived Ingredients as Used in Cosmetics