Derm Institute Cellular Rejuvenating Serum
Works for
MoisturizingTrifluoroacetyl tripeptide-2, Palmitoyl tripeptide-5 + 23 moreWorks well
“For extra hydration, follow by applying a moisturising lotion or cream.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
dextran, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-15, acetyl tetrapeptide-17, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tripeptide-5, trifluoroacetyl tripeptide-2
Anti-agingTrifluoroacetyl tripeptide-2, Palmitoyl tripeptide-5 + 7 moreMay help
“Key Benefits Works to firm, contour and boost natural plumpness Protects against environmental stressors Supports the skin’s natural barrier function Rich in antioxidants and vitamins Features an anti-stress complex Suitable for all skin types UK300025794”
This product contains acetyl tetrapeptide-15, acetyl tetrapeptide-17, adenosine triphosphate, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tripeptide-5, trifluoroacetyl tripeptide-2. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Anti-oxidationSide benefit · Ubiquinone, Superoxide dismutase + 5 moreWorks well
This product contains antioxidants (superoxide dismutase, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy8 strong irritants: Withania somnifera root extract, Citral + 6 more — patch-test recommendedHigh risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Methyl gluceth-10~4.3–5.3%
Dipropylene glycol~4.1–5%
- Irritation risk
- Low
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
More about Dipropylene glycolGlycerin~3–3.6%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPentylene glycol~2.3–2.8%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolDimethicone~1.9–2.4%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeSqualane~1.6–2%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneWithania somnifera root extract~1.3–1.6%
- Irritation risk
- High
Tocopheryl acetate~1.1–1.3%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateBacopa monnieri extract~0.9–1.1%
- Irritation risk
- Low
Caprylic/capric triglyceride~0.75–1.1%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideHydrolyzed jojoba esters~0.6–0.9%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Hydrolyzed jojoba estersSodium hyaluronate~0.5–0.75%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateTrifluoroacetyl tripeptide-2~0.45–0.7%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Trifluoroacetyl tripeptide-2Acetyl tyrosine~0.45–0.65%
- Irritation risk
- Low
Corallina officinalis extract~0.45–0.65%
- Irritation risk
- Low
- Comedogenicity
- 3/5
Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants
More about Corallina officinalis extractPalmitoyl tripeptide-5~0.45–0.7%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-5Hydrolyzed vegetable protein~0.4–0.65%
Adenosine triphosphate~0.35–0.65%
Scutellaria alpina flower/leaf/stem extract~0.3–0.6%
- Irritation risk
- Low
Ubiquinone~0.35–0.6%
- Irritation risk
- Low
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
More about UbiquinoneAscorbic acid~0.3–0.55%
- Irritation risk
- High
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
More about Ascorbic acidDipeptide diaminobutyroyl benzylamide diacetate~0.3–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Dipeptide diaminobutyroyl benzylamide diacetateAcetyl tetrapeptide-15~0.3–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl tetrapeptide-15Ergothioneine~0.3–0.55%
- Irritation risk
- Low
Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking
More about ErgothioneineAcetyl tetrapeptide-17~0.3–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl tetrapeptide-17Colloidal platinum~0.3–0.55%
- Irritation risk
- Low
Cyclopentasiloxane~0.35–0.6%
- Irritation risk
- Low
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
More about CyclopentasiloxaneIsononyl isononanoate~0.3–0.6%
- Irritation risk
- Low
Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness
More about Isononyl isononanoateSodium polyacrylate~0.35–0.6%
- Irritation risk
- Low
Used to create a gel-like product texture, as well as to stabilize emulsions
More about Sodium polyacrylateAmmonium acryloyldimethyltaurate/vp copolymer~0.3–0.55%
- Irritation risk
- Low
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
More about Ammonium acryloyldimethyltaurate/vp copolymerPhenoxyethanol~0.3–0.55%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolMannitol~0.3–0.5%
- Irritation risk
- Low
Helps to attract water to the upper layer of the skin
More about MannitolChlorphenesin~0.16–0.32%
Butylene glycol~0.3–0.55%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolTrideceth-6~0.3–0.55%
Peg/ppg-18/18 dimethicone~0.3–0.6%
- Irritation risk
- Low
A silicone that mixes with water creating nice light-weight product texture
More about Peg/ppg-18/18 dimethiconeDextran~0.3–0.55%
- Irritation risk
- Low
Helps attract water to the most upper layer of the skin. Derived from sugar
More about DextranDimethicone/vinyl dimethicone crosspolymer~0.3–0.55%
- Irritation risk
- Low
Used to stabilize product formulations and create a nice product texture
More about Dimethicone/vinyl dimethicone crosspolymerEthylhexylglycerin~0.3–0.55%
Disodium acetyl glucosamine phosphate~0.3–0.5%
- Irritation risk
- Low
Sodium glucuronate~0.3–0.5%
- Irritation risk
- Low
Proline~0.3–0.55%
Sodium citrate~0.3–0.55%
- Irritation risk
- Medium
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products
More about Sodium citratePropanediol~0.3–0.55%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolMagnesium sulfate~0.3–0.55%
Hydroxyethylcellulose~0.3–0.6%
- Irritation risk
- Low
Used to thicken product formulations and create gel-like textures
More about HydroxyethylcelluloseSuperoxide dismutase~0.3–0.55%
- Irritation risk
- Low
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
More about Superoxide dismutasePeg-35 castor oil~0.3–0.6%
Peg-12 glyceryl laurate~0.3–0.6%
Teprenone~0.3–0.5%
- Irritation risk
- Low
Potassium sorbate~0.3–0.55%
Citric acid~0.3–0.5%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidSodium benzoate~0.25–0.5%
Tocopherol~0.25–0.5%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolPvp~0.25–0.5%
- Irritation risk
- Medium
Helps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin
More about PvpDisodium edta~0.25–0.45%
Biotin~0.2–0.4%
- Irritation risk
- Low
Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect
More about BiotinBenzyl alcohol~0.15–0.3%
- Irritation risk
- High
A preservative. Can be used to mask unpleasant smell. Can be irritating
More about Benzyl alcoholCitral~0.15–0.3%
Citronellol~0.15–0.25%
Geraniol~0.1–0.2%
Hexyl cinnamal~0.15–0.25%
Limonene~0.1–0.2%
- Irritation risk
- High
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
More about LimoneneLinalool~0.05–0.15%
Parfum~0.05–0.1%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumIngredient list view
Water, Methyl gluceth-10, Dipropylene glycol, Glycerin, Pentylene glycol, Dimethicone, Squalane, Withania somnifera root extract, Tocopheryl acetate, Bacopa monnieri extract, Caprylic/capric triglyceride, Hydrolyzed jojoba esters, Sodium hyaluronate, Trifluoroacetyl tripeptide-2, Acetyl tyrosine, Corallina officinalis extract, Palmitoyl tripeptide-5, Hydrolyzed vegetable protein, Adenosine triphosphate, Scutellaria alpina flower/leaf/stem extract, Ubiquinone, Ascorbic acid, Dipeptide diaminobutyroyl benzylamide diacetate, Acetyl tetrapeptide-15, Ergothioneine, Acetyl tetrapeptide-17, Colloidal platinum, Cyclopentasiloxane, Isononyl isononanoate, Sodium polyacrylate, Ammonium acryloyldimethyltaurate/vp copolymer, Phenoxyethanol, Mannitol, Chlorphenesin, Butylene glycol, Trideceth-6, Peg/ppg-18/18 dimethicone, Dextran, Dimethicone/vinyl dimethicone crosspolymer, Ethylhexylglycerin, Disodium acetyl glucosamine phosphate, Sodium glucuronate, Proline, Sodium citrate, Propanediol, Magnesium sulfate, Hydroxyethylcellulose, Superoxide dismutase, Peg-35 castor oil, Peg-12 glyceryl laurate, Teprenone, Potassium sorbate, Citric acid, Sodium benzoate, Tocopherol, Pvp, Disodium edta, Biotin, Benzyl alcohol, Citral, Citronellol, Geraniol, Hexyl cinnamal, Limonene, Linalool, Parfum
Compare prices
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Derm InstituteCellular Rejuvenating SerumYOUR PRODUCT | Peter Thomas RothPeptide 21 Wrinkle Resist Serum | Sarah Chapman LondonSerum & Treatment Skinesis Platinum Pep⁸ Stem Cell Serum | Sarah ChapmanPlatinum Pep8 Stem Cell Serum | |
|---|---|---|---|---|
| Match | — | 49% | 49% | 49% |
| Price | $126.00 | $125.00−$1.00 | — | $206.50+$80.50 |
| Shared key ingredients | — | 8 of 22 | 6 of 22 | 6 of 22 |
| Key difference | — | Acetyl Octapeptide-3 | N-Prolyl Palmitoyl Tripeptide-56 Acetate | N-Prolyl Palmitoyl Tripeptide-56 Acetate |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Farm Stay Black Snail & Peptide9 Perfect SerumRevivSerums TelomErase 6-in-1 Multi-Corrective Serum - NEW & IMPROVED
Product summary
"Derm Institute - Cellular Rejuvenating Serum" is effective for: Moisturizing
This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.30% - 0.55%) it cannot have a noticeable benefit for the skin.
- Peptides (trifluoroacetyl tripeptide-2 0.45% - 0.70%, palmitoyl tripeptide-5 0.45% - 0.70%, dipeptide diaminobutyroyl benzylamide diacetate 0.30% - 0.50%, acetyl tetrapeptide-17 0.30% - 0.50% and acetyl tetrapeptide-15 0.30% - 0.50%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Humectants (dextran 0.30% - 0.55%, mannitol 0.30% - 0.50%, sodium hyaluronate 0.50% - 0.75% and glycerin 3.00% - 3.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails from 105.00£ up to 120.00£ in the United Kingdom and for 126.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.
- 1
- 2
- 3Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 4Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 5
- 6A comparison of the relative antioxidant potency of L‐ergothioneine and idebenoneonlinelibrary.wiley.com
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