PRODUCT REVIEW

Darphin Predermine Anti-Wrinkle Cream for Normal Skin

Works for:

based on ingredients and %

Moisturizing
Anti-aging

Can it cause trouble?

Key actives

Acetyl glucosamine 0.15% - 0.3%Rosmarinus officinalis leaf extract 0.25% - 0.5%

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Buy from Amazon US $73.24

Price as of 2/11/2023 4:13 GMT. More info

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Clinique - Smart Clinical Repair™ Wrinkle Correcting Cream

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Product summary

Based on the ingredients included, "Darphin - Predermine Anti-Wrinkle Cream for Normal Skin" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Algae extract, glycerin, sodium hyaluronate, glucose and glycine soja protein in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (algae extract, caprylic/capric triglyceride, dimethicone, helianthus annuus seed oil and ethylhexyl palmitate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We like that this moisturizer contains peptides (palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine 0.80% - 1.20%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 399.00A$ in Australia, for 95.26$ in the United States and for 89.00£ in the United Kingdom.

For a detailed price comparison: click here.

What can the product work for?

Anti-aging

What does the product description say?

Predermine Anti-Wrinkle Cream for Normal Skin

Source: From product name

This product contains arabidopsis thaliana extract, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine 0.8% - 1.2%

Irritation risk:

Concentration: Effectiveness: MEDIUM

arabidopsis thaliana extract 0.35% - 0.65%

Irritation risk:

Concentration: Effectiveness: MEDIUM

Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking

glycine soja protein 0.35% - 0.6%

Irritation risk:

Concentration: Effectiveness: LOW

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

Moisturizing

What does the product description say?

Predermine Anti-Wrinkle Cream for Normal Skin

Source: From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine

dimethicone 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

sodium hyaluronate 0.5% - 0.75%

Irritation risk:

Concentration: Effectiveness: HIGH

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

helianthus annuus seed oil 0.25% - 0.5%

Irritation risk:

Concentration: Effectiveness: HIGH

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

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Ingredients & concentrations

All ingredients

Key Actives

acetyl glucosamine 0.15% - 0.3%

Irritation risk:

Works for: Moisturizing, Anti-aging, Evens skin tone, Exfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

rosmarinus officinalis leaf extract 0.25% - 0.5%

Irritation risk:

Works for: Anti-blemish, Antibacterial, Anti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

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Potential irritants

rosmarinus officinalis leaf extract 0.25% - 0.5%

Irritation risk:

Works for: Anti-blemish, Antibacterial, Anti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

equisetum arvense extract 0.15% - 0.3%

Irritation risk:

A plant extract that might have anti-oxidant properties. Can be irritating

Comodogenic ingredients

padina pavonica thallus extract 0.3% - 0.55%

Irritation risk: Comedogenicity: High

Works for: Moisturizing, Anti-oxidation

Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing

hypnea musciformis extract 0.2% - 0.35%

Irritation risk: Comedogenicity: High

Works for: Moisturizing

Might help to attract water to the upper layer of the skin

All ingredients

water 45% - 55%

Irritation risk:

Plain old water

glyceryl stearate 4.6% - 5.6%

Irritation risk:

Works for: Cleansing, Moisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

caprylic/capric triglyceride 4.2% - 5.2%

Irritation risk:

Works for: Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

Ingredient list view

Water, Glyceryl stearate, Caprylic/capric triglyceride, Hydrogenated polydecene, Butylene glycol, Glycerin, Palmitic acid, Stearic acid, Iris florentina root extract, Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, Palmitoyl dipeptide-5 diaminohydroxybutyrate, Sodium hyaluronate, Oryza sativa bran extract, Arabidopsis thaliana extract, Padina pavonica thallus extract, Glycine soja protein, Rosmarinus officinalis leaf extract, Menyanthes trifoliata leaf extract, Helianthus annuus seed oil, Helianthus annuus seedcake, Tocopheryl acetate, Hypnea musciformis extract, Algae extract, Hordeum vulgare extract, Equisetum arvense extract, Butyrospermum parkii butter, Cucumis sativus fruit extract, Hibiscus sabdariffa flower extract, Simmondsia chinensis seed oil, Phytic acid, Tocopherol, Propylene glycol dicaprate, Sodium stearate, Isononyl isononanoate, Potassium cetyl phosphate, Beheneth-25, Caprylyl methicone, Ethylhexyl palmitate, Acetyl glucosamine, Caffeine, Dimethicone, Acrylates/c10-30 alkyl acrylate crosspolymer, Ethylhexylglycerin, Silica dimethyl silylate, Chondrus crispus, Carrageenan, Benzophenone-4, Glucose, Xanthan gum, Caprylyl glycol, Lecithin, Hexylene glycol, Tetrasodium edta, Phenoxyethanol, Chlorphenesin, Parfum, Butylphenyl methylpropional, Hydroxyisohexyl 3-cyclohexene carboxaldehyde, Alpha-isomethyl ionone, Citronellol, Benzyl salicylate, Hydroxycitronellal, Geraniol, Linalool, Limonene, Benzyl benzoate, Hexyl cinnamal, Coumarin, Eugenol, Citral, Ci 14700

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Price
WIMJ similarity score		49%	48%	46%	45%	45%	45%	45%	45%	44%	43%
Key ingredients	palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine acetyl glucosamine +13 more	Common: acetyl glucosamine algae extract +5 more Other: acetyl hexapeptide-8 glucose oxidase +4 more	Common: acetyl glucosamine algae extract +4 more Other: acetyl octapeptide-3 aminopropyl ascorbyl phosphate +7 more	Common: acetyl glucosamine caprylic/capric triglyceride +3 more Other: argania spinosa kernel oil camellia sinensis leaf extract +3 more	Common: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine glycerin +4 more Other: retinol linoleic acid +13 more	Common: acetyl glucosamine dimethicone +4 more Other: niacinamide adenosine +12 more	Common: acetyl glucosamine glycerin +2 more Other: ceramide np panthenol +23 more	Common: acetyl glucosamine glycerin +3 more Other: niacinamide acetyl dipeptide-1 cetyl ester +14 more	Common: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine dimethicone +3 more Other: palmitoyl tripeptide-5 hydrolyzed collagen +6 more	Common: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine glycerin +3 more Other: anhydroxylitol retinyl palmitate +15 more	Common: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine caprylic/capric triglyceride +4 more Other: glycine soja oil imperata cylindrica root extract +5 more
Irritancy	IRRITANCY HIGH	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY LOW	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY HIGH
Potential Irritants	citral Has skin benefit? eugenol Has skin benefit? +35 more	parfum Has skin benefit? rosa damascena extract Has skin benefit? +22 more	potassium sorbate Has skin benefit? disodium edta Has skin benefit? +13 more	disodium edta Has skin benefit? caprylyl glycol Has skin benefit? +8 more	anogeissus leiocarpus bark extract Has skin benefit? retinol Has skin benefit? +11 more	ocimum sanctum leaf extract Has skin benefit? curcuma longa root extract Has skin benefit? +15 more	citrus unshiu peel extract Has skin benefit? anthemis nobilis flower oil Has skin benefit? +18 more	parfum Has skin benefit? vaccinium macrocarpon fruit extract Has skin benefit? +17 more	decyl glucoside Has skin benefit? ethylhexylglycerin Has skin benefit? +9 more	retinyl palmitate Has skin benefit? taurine Has skin benefit? +10 more	rosmarinus officinalis leaf extract Has skin benefit? citronellol Has skin benefit? +22 more
All ingredients	water Has skin benefit? glyceryl stearate Has skin benefit? +69 more	water Has skin benefit? isononyl isononanoate Has skin benefit? +56 more	water Has skin benefit? glycerin Has skin benefit? +42 more	water Has skin benefit? caprylic/capric triglyceride Has skin benefit? +27 more	water Has skin benefit? glycerin Has skin benefit? +55 more	cream Has skin benefit? water Has skin benefit? +55 more	water Has skin benefit? glycerin Has skin benefit? +68 more	water Has skin benefit? isononyl isononanoate Has skin benefit? +67 more	unknown Has skin benefit? collagen water Has skin benefit? +36 more	water Has skin benefit? c12-15 alkyl benzoate Has skin benefit? +45 more	water Has skin benefit? glycerin Has skin benefit? +54 more

PRODUCT REVIEW

Darphin Predermine Anti-Wrinkle Cream for Normal Skin

Works for:

Can it cause trouble?

Key actives

Cheaper alternatives

Product summary

Ingredient callouts

Irritation risk

Price

What can the product work for?

Works for

Anti-aging

What does the product description say?

Moisturizing

What does the product description say?

Honesty check

How honest is this product?

Buy now

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Can it cause trouble?

Potential irritants

Comodogenic ingredients

User reviews (0)

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Ingredients & concentrations

All ingredients

Key Actives

Potential irritants

Comodogenic ingredients

All ingredients

Ingredient list view

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