La Mer

La Mer The Regenerating Serum

Name: La Mer - The Regenerating Serum
Brand: La Mer

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Anti-aging

Palmitoyl oligopeptide, Acetyl hexapeptide-8 + 8 more

Works well

What the product description says

“This potent serum rapidly diminishes the look of lines and wrinkles.”

Source: La mer

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, palmitoyl oligopeptide, vitis vinifera seed extract.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.15–0.3%

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.15–0.3%

Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~6.1–7.5%

Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.2–0.4%

Dipalmitoyl hydroxyprolineEffect: LowIs claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness~0.15–0.3%

Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%

Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.1–0.25%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.25%

Evens skin tone

Side benefit · Acetyl glucosamine, Glycine soja seed extract + 7 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja seed extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.2–0.4%

Yeast extractEffect: Low, below effective doseHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.5–0.75%

Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%

Bifida ferment lysateEffect: Low, below effective doseConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.2–0.35%

Narcissus tazetta bulb extractEffect: Low, below effective doseMight contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lacking~0.15–0.25%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.25%

Moisturizing

Side benefit the brand mentions · Linoleic acid, Palmitoyl oligopeptide + 45 more

Works well

What the product description says

“Skin Type All Skin Types Combination Skin Dry Skin Balanced Skin Oily Skin Targeting Dullness Fine Lines & Wrinkles Dehydration Renew skin and diminish fine lines with the La Mer Regenerating Serum.”

Source: SpaceNK

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alcaligenes polysaccharides, algae extract.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, peg-10 dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, linoleic acid, palmitoyl oligopeptide, tetraacetylphytosphingosine

Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.3–0.55%

Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

TetraacetylphytosphingosineHeroEffect: High~0.15–0.3%

Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.15–0.3%

Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~6.1–7.5%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.4–5.3%

Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~1.8–2.2%

Peg-10 dimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that works to soften the upper layer of the skin and reduce its water loss~0.75–1.1%

Linolenic acidKey active· EmollientEffect: HighAn emollient that helps soften the skin and calm down inflammation~0.3–0.6%

Sesamum indicum seed oilKey active· EmollientEffect: HighA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function~0.3–0.55%

PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.25–0.45%

Saccharomyces lysate extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Can have some anti-inflammatory effect~0.25–0.5%

GlycosaminoglycansKey active· EmollientEffect: HighLong sugars that help attract water to the upper layer of the skin~0.25–0.5%

Alcaligenes polysaccharidesKey active· Humectant, EmollientEffect: HighHelp attract water to the upper layer of the skin~0.2–0.35%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.2–0.35%

Glycine soja seed extractKey active· EmollientEffect: MediumAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.2–0.4%

Medicago sativa seed powderKey activeEffect: MediumMight help soften the upper layer of the skin and help thicken the product formulation. It might have some anti-oxidant effect~0.2–0.35%

Micrococcus lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.15–0.3%

SucroseKey active· HumectantEffect: HighCan help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion~0.15–0.3%

Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.15–0.25%

Tartaric acidKey activeEffect: MediumAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels~0.15–0.3%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.15–0.25%

Dipalmitoyl hydroxyprolineKey activeEffect: MediumIs claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness~0.15–0.3%

Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.15–0.3%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~2.3–2.9%

Caprylic/capric/myristic/stearic triglyceride· EmollientEffect: LowHelps to soften the upper layer of the skin~1.5–1.9%

Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~1.3–1.6%

Peg-8 dimethiconeEffect: LowA type of silicone that can help create nice product texture and soften the upper layer of the skin~1–1.2%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.25–0.45%

Glyceryl polymethacrylate· Humectant, EmollientEffect: LowUsed to create a nice product texture~0.25–0.5%

Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.25–0.5%

Whey protein· EmollientEffect: LowA protein derived from milk. In skincare products, might help to soften the upper layer of the skin~0.2–0.35%

Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.2–0.4%

Peg-8· HumectantEffect: LowUsed to create a nice product consistency~0.2–0.4%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.2–0.35%

Calcium gluconate· HumectantEffect: LowHelps attract water to the upper layer of the skin and helps to improve appearance of the product~0.15–0.3%

Coenzyme aEffect: LowHelps soften the upper layer of the skin and dissolve other ingredients in a product~0.15–0.3%

Magnesium gluconateEffect: LowA mineral that might be able to support skin hydration, but convincing research on its effectiveness in topical skincare is lacking~0.15–0.25%

Bupleurum falcatum root extractEffect: LowA plant extract that might help to attract water to the upper layer of the skin, but it is not well studied. It can be irritating~0.15–0.25%

Betula alba bark extractEffect: Low, below effective doseHas astringent properties. Creates a tightening and drying effect on the skin. Can be irritating~0.1–0.2%

Yeast extractUnder-dosedHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.5–0.75%

Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%

Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.2–0.35%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.25%

Copper gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%

Zinc gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.1–0.25%

Anti-oxidation

Side benefit · Ethylbisiminomethylguaiacol manganese chloride, Vitis vinifera seed extract + 19 more

Works well

This product contains antioxidants (ethylbisiminomethylguaiacol manganese chloride, vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - tartaric acid also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Ethylbisiminomethylguaiacol manganese chlorideKey activeEffect: HighA potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications~0.25–0.45%

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.15–0.3%

Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.2–0.4%

Medicago sativa seed powderEffect: LowMight help soften the upper layer of the skin and help thicken the product formulation. It might have some anti-oxidant effect~0.2–0.35%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.2–0.35%

Chlorella vulgaris extractEffect: LowA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.15–0.25%

Micrococcus lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.15–0.3%

Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.15–0.25%

Citrus reticulata peel extractEffect: LowA likely irritant. Might have some anti-oxidant activity, but is mostly used as a fragrance in cosmetic products~0.15–0.25%

Punica granatum fruit juiceEffect: LowA fruit juice. Might have some anti-oxidant properties but is unlikely to have any benefit when used in skincare~0.1–0.25%

Polygonum cuspidatum root extractEffect: Low, below effective doseA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product~0.3–0.6%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.45%

Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.1–0.2%

Betula alba bark extractEffect: Low, below effective doseHas astringent properties. Creates a tightening and drying effect on the skin. Can be irritating~0.1–0.2%

Yeast extractUnder-dosedHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.5–0.75%

Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.2–0.35%

Can it cause trouble?

Irritancy

11 strong irritants: Citrus aurantifolia peel extract, Eucalyptus globulus leaf oil + 9 more — patch-test recommended

High risk

We flagged 40 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Citrus aurantifolia peel extract—High~0.45–0.65%est.

Eucalyptus globulus leaf oilAn essential oil that can be very irritating. Has some anti-bacterial propertiesHigh~0.2–0.4%est.

NiacinA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effectHigh~0.15–0.25%est.

Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.1–0.2%est.

Bupleurum falcatum root extractA plant extract that might help to attract water to the upper layer of the skin, but it is not well studied. It can be irritatingHigh~0.15–0.25%est.

Citrus reticulata peel extractA likely irritant. Might have some anti-oxidant activity, but is mostly used as a fragrance in cosmetic productsHigh~0.15–0.25%est.

Betula alba bark extractHas astringent properties. Creates a tightening and drying effect on the skin. Can be irritatingHigh~0.1–0.2%est.

Humulus lupulus extractHops extract. Can contain common irritants and allergens geraniol, limonene, linaloolHigh~0.15–0.25%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.35%est.

HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.15–0.3%est.

LinaloolA fragrance. Can be irritatingHigh~0.15–0.3%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.15–0.25%est.

CitronellolA fragrance. Can be irritatingHigh~0.15–0.3%est.

GeraniolA fragrance. Can be irritatingHigh~0.15–0.25%est.

Sigesbeckia orientalis extractA plant extract that can contain an anti-inflammatory compoundMedium~0.3–0.55%est.

Polygonum cuspidatum root extractA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the productMedium~0.3–0.6%est.

Medicago sativa seed powderMight help soften the upper layer of the skin and help thicken the product formulation. It might have some anti-oxidant effectMedium~0.2–0.35%est.

Copper gluconateTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missingMedium~0.15–0.25%est.

Zinc gluconateTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skinMedium~0.1–0.25%est.

Tocopheryl succinateUsed to preserve the product formulationMedium~0.15–0.25%est.

Punica granatum fruit juiceA fruit juice. Might have some anti-oxidant properties but is unlikely to have any benefit when used in skincareMedium~0.1–0.25%est.

Narcissus tazetta bulb extractMight contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lackingMedium~0.15–0.25%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.15–0.25%est.

Laureth-4Helps water and oil mix togetherMedium~0.15–0.3%est.

Glycine soja seed extractAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.Medium~0.2–0.4%est.

Tartaric acidAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levelsMedium~0.15–0.3%est.

Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.15–0.3%est.

Laureth-23Helps oil and water mix togetherMedium~0.25–0.45%est.

Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymerUsed to stabilize product formulationsMedium~0.2–0.35%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.2–0.35%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.25–0.45%est.

Peg-8Used to create a nice product consistencyMedium~0.2–0.4%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.

Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.25–0.5%est.

Nordihydroguaiaretic acidUsed to stabilize the formula of product formulation. Might be helpful in neutralizing free radicals in skinMedium~0.25–0.45%est.

GoldA colorant. Does not have any proven benefits in skinMedium~0.25–0.45%est.

Linolenic acidAn emollient that helps soften the skin and calm down inflammationMedium~0.3–0.6%est.

Ethylbisiminomethylguaiacol manganese chlorideA potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applicationsMedium~0.25–0.45%est.

Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.

Potassium sorbateA preservativeMedium~0.25–0.45%est.

Comedogenic

6 ingredients rated 2 or more on the 0–5 pore-clogging scale

6 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~6.1–7.5%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.15–0.25%est.

Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.15–0.25%est.

Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~1.8–2.2%est.

Laureth-4Helps water and oil mix together2/5~0.15–0.3%est.

Laureth-23Helps oil and water mix together2/5~0.25–0.45%est.

Alternatives

The closest match we found

Estée Lauder Perfectionist [CP+R] - Wrinkle Lifting/Firming Serum

Closest match51% match

$116.00

View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Algae extract~6.1–7.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract

Dimethicone~4.4–5.3%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Hdi/trimethylol hexyllactone crosspolymer~3–3.7%

Formula

Irritation risk: Low

Used to create a silky product texture and add volume to products

More about Hdi/trimethylol hexyllactone crosspolymer

Hydrogenated polyisobutene~2.3–2.9%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Hydrogenated vegetable oil~1.8–2.2%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil

Caprylic/capric/myristic/stearic triglyceride~1.5–1.9%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin

More about Caprylic/capric/myristic/stearic triglyceride

Polysilicone-11~1.3–1.6%

Formula

Irritation risk: Low

Works for

MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11

Peg-8 dimethicone~1–1.2%

Formula

Irritation risk: Low

Works for

Moisturizing

A type of silicone that can help create nice product texture and soften the upper layer of the skin

More about Peg-8 dimethicone

Peg-10 dimethicone~0.75–1.1%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that works to soften the upper layer of the skin and reduce its water loss

More about Peg-10 dimethicone

Yeast extract~0.5–0.75%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-oxidationReduces irritationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract

Citrus aurantifolia peel extract~0.45–0.65%

Irritant · high

Irritation risk: High

More about Citrus aurantifolia peel extract

Sigesbeckia orientalis extract~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatory

A plant extract that can contain an anti-inflammatory compound

More about Sigesbeckia orientalis extract

Polygonum cuspidatum root extract~0.3–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product

More about Polygonum cuspidatum root extract

Saccharomyces lysate extract~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect

More about Saccharomyces lysate extract

Sesamum indicum seed oil~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function

More about Sesamum indicum seed oil

Eucalyptus globulus leaf oil~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Antibacterial

An essential oil that can be very irritating. Has some anti-bacterial properties

More about Eucalyptus globulus leaf oil

Sesamum indicum seed powder~0.2–0.4%

Formula

Irritation risk: Low

More about Sesamum indicum seed powder

Medicago sativa seed powder~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

Might help soften the upper layer of the skin and help thicken the product formulation. It might have some anti-oxidant effect

More about Medicago sativa seed powder

Helianthus annuus seedcake~0.25–0.5%

Formula

Irritation risk: Low

Used to thicken the product consistency

More about Helianthus annuus seedcake

Prunus amygdalus dulcis seed meal~0.25–0.45%

Formula

Irritation risk: Low

Helps thicken the product texture

More about Prunus amygdalus dulcis seed meal

Sodium gluconate~0.15–0.25%

Formula

Irritation risk: Low

Helps stabilize product formulations

More about Sodium gluconate

Copper gluconate~0.15–0.25%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingEvens skin toneAnti-blemishExfoliationAnti-oxidationAnti-aging

Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing

More about Copper gluconate

Calcium gluconate~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and helps to improve appearance of the product

More about Calcium gluconate

Magnesium gluconate~0.15–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

A mineral that might be able to support skin hydration, but convincing research on its effectiveness in topical skincare is lacking

More about Magnesium gluconate

Zinc gluconate~0.1–0.25%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingEvens skin toneAnti-oxidationAnti-agingAnti-blemishAnti-inflammatoryExfoliation

Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin

More about Zinc gluconate

Tocopheryl succinate~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Used to preserve the product formulation

More about Tocopheryl succinate

Niacin~0.15–0.25%

Under-dosedIrritant · high

Irritation risk: High

Works for

MoisturizingEvens skin toneAnti-agingAnti-blemish

A form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect

More about Niacin

Vitis vinifera seed extract~0.15–0.3%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract

Rosmarinus officinalis leaf extract~0.1–0.2%

Irritant · high

Irritation risk: High

Works for

Anti-blemishAntibacterialAnti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract

Punica granatum fruit juice~0.1–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A fruit juice. Might have some anti-oxidant properties but is unlikely to have any benefit when used in skincare

More about Punica granatum fruit juice

Bupleurum falcatum root extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Moisturizing

A plant extract that might help to attract water to the upper layer of the skin, but it is not well studied. It can be irritating

More about Bupleurum falcatum root extract

Citrus reticulata peel extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A likely irritant. Might have some anti-oxidant activity, but is mostly used as a fragrance in cosmetic products

More about Citrus reticulata peel extract

Narcissus tazetta bulb extract~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-oxidation

Might contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lacking

More about Narcissus tazetta bulb extract

Mimosa tenuiflora bark extract~0.1–0.2%

Formula

Irritation risk: Low

More about Mimosa tenuiflora bark extract

Betula alba bark extract~0.1–0.2%

Irritant · high

Irritation risk: High

Works for

MoisturizingAnti-oxidation

Has astringent properties. Creates a tightening and drying effect on the skin. Can be irritating

More about Betula alba bark extract

Chlorella vulgaris extract~0.15–0.25%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-inflammatory

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Humulus lupulus extract~0.15–0.25%

Irritant · high

Irritation risk: High

Hops extract. Can contain common irritants and allergens geraniol, limonene, linalool

More about Humulus lupulus extract

Laureth-4~0.15–0.3%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps water and oil mix together

More about Laureth-4

Corallina officinalis extract~0.15–0.25%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract

Glycine soja seed extract~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-agingAnti-oxidationEvens skin toneReduces redness

An emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.

More about Glycine soja seed extract

Micrococcus lysate~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-oxidation

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"

More about Micrococcus lysate

Whey protein~0.2–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

A protein derived from milk. In skincare products, might help to soften the upper layer of the skin

More about Whey protein

Tartaric acid~0.15–0.3%

Key activeIrritant · medium

Irritation risk: Medium

Works for

ExfoliationAnti-oxidationMoisturizing

An AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels

More about Tartaric acid

Glycerin~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Hydrolyzed wheat protein~0.15–0.3%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein

Laureth-23~0.25–0.45%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together

More about Laureth-23

Butylene glycol~0.2–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Used to stabilize product formulations

More about Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer

Sucrose~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Can help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion

More about Sucrose

Coenzyme a~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and dissolve other ingredients in a product

More about Coenzyme a

Acetyl glucosamine~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine

Caffeine~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Dipalmitoyl hydroxyproline~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness

More about Dipalmitoyl hydroxyproline

Linoleic acid~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

CleansingMoisturizingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid

Tetraacetylphytosphingosine~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

Moisturizing

More about Tetraacetylphytosphingosine

Alcaligenes polysaccharides~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Help attract water to the upper layer of the skin

More about Alcaligenes polysaccharides

Bifida ferment lysate~0.2–0.35%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate

Pentylene glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Dipotassium glycyrrhizate~0.2–0.35%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Palmitoyl oligopeptide~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingCleansingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide

Peg-8~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to create a nice product consistency

More about Peg-8

Sorbitol~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol

Tocopheryl acetate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Eryngium maritimum extract~0.2–0.4%

Formula

Irritation risk: Low

More about Eryngium maritimum extract

Sodium hydroxide~0.25–0.45%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Hydrogenated lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Hydroxypropyl cyclodextrin~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin

Nordihydroguaiaretic acid~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Used to stabilize the formula of product formulation. Might be helpful in neutralizing free radicals in skin

More about Nordihydroguaiaretic acid

Cyclodextrin~0.25–0.45%

Formula

Irritation risk: Low

A type of sugar that is used to support delivery of active ingredients and can enhance their penetration into the skin without disrupting the skin's barrier

More about Cyclodextrin

Maltodextrin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Polymethylsilsesquioxane~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane

Acetyl hexapeptide-8~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Glyceryl polymethacrylate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture

More about Glyceryl polymethacrylate

Glycosaminoglycans~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Glycosaminoglycans

Gold~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A colorant. Does not have any proven benefits in skin

More about Gold

Tourmaline~0.25–0.4%

Formula

Irritation risk: Low

More about Tourmaline

Linolenic acid~0.3–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingCleansingReduces irritationAnti-inflammatory

An emollient that helps soften the skin and calm down inflammation

More about Linolenic acid

Silica~0.35–0.6%

Formula

Irritation risk: Low

Used to absorb oil and can temporarily mattify skin

More about Silica

Ethylbisiminomethylguaiacol manganese chloride~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications

More about Ethylbisiminomethylguaiacol manganese chloride

Disodium edta~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Potassium sorbate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Phenoxyethanol~0.25–0.4%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Parfum~0.2–0.35%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Hydroxycitronellal~0.15–0.3%

Irritant · high

Irritation risk: High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal

Linalool~0.15–0.3%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Limonene~0.15–0.25%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Citronellol~0.15–0.3%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Citronellol

Geraniol~0.15–0.25%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Geraniol

Ci 61570~0.1–0.2%

Formula

Irritation risk: Low

More about Ci 61570

Ingredient list view

Water, Algae extract, Dimethicone, Hdi/trimethylol hexyllactone crosspolymer, Hydrogenated polyisobutene, Hydrogenated vegetable oil, Caprylic/capric/myristic/stearic triglyceride, Polysilicone-11, Peg-8 dimethicone, Peg-10 dimethicone, Yeast extract, Citrus aurantifolia peel extract, Sigesbeckia orientalis extract, Polygonum cuspidatum root extract, Saccharomyces lysate extract, Sesamum indicum seed oil, Eucalyptus globulus leaf oil, Sesamum indicum seed powder, Medicago sativa seed powder, Helianthus annuus seedcake, Prunus amygdalus dulcis seed meal, Sodium gluconate, Copper gluconate, Calcium gluconate, Magnesium gluconate, Zinc gluconate, Tocopheryl succinate, Niacin, Vitis vinifera seed extract, Rosmarinus officinalis leaf extract, Punica granatum fruit juice, Bupleurum falcatum root extract, Citrus reticulata peel extract, Narcissus tazetta bulb extract, Mimosa tenuiflora bark extract, Betula alba bark extract, Chlorella vulgaris extract, Humulus lupulus extract, Laureth-4, Corallina officinalis extract, Glycine soja seed extract, Micrococcus lysate, Whey protein, Tartaric acid, Glycerin, Hydrolyzed wheat protein, Laureth-23, Butylene glycol, Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer, Sucrose, Coenzyme a, Acetyl glucosamine, Caffeine, Dipalmitoyl hydroxyproline, Linoleic acid, Tetraacetylphytosphingosine, Alcaligenes polysaccharides, Bifida ferment lysate, Pentylene glycol, Dipotassium glycyrrhizate, Palmitoyl oligopeptide, Peg-8, Sorbitol, Tocopheryl acetate, Eryngium maritimum extract, Sodium hydroxide, Hydrogenated lecithin, Hydroxypropyl cyclodextrin, Nordihydroguaiaretic acid, Cyclodextrin, Maltodextrin, Polymethylsilsesquioxane, Acetyl hexapeptide-8, Glyceryl polymethacrylate, Glycosaminoglycans, Gold, Tourmaline, Linolenic acid, Silica, Ethylbisiminomethylguaiacol manganese chloride, Disodium edta, Potassium sorbate, Phenoxyethanol, Parfum, Hydroxycitronellal, Linalool, Limonene, Citronellol, Geraniol, Ci 61570

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	La MerThe Regenerating SerumYOUR PRODUCT	Estée LauderPerfectionist [CP+R] - Wrinkle Lifting/Firming Serum	CliniqueSmart Custom-Repair Serum	Tom FordResearch Serum Concentrate
Match	—	51%	48%	43%
Price	$409.50	$116.00−$293.50	—	$18.88−$390.62
Shared key ingredients	—	12 of 27	12 of 27	9 of 27
Key difference	—	Aminopropyl Ascorbyl Phosphate	Salicylic Acid	Lactic Acid
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Crème de la Mer - The Regenerating Serum" is effective for: Moisturizing

This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

Ceramides (tetraacetylphytosphingosine 0.15% - 0.30% and tetraacetylphytosphingosine 0.10% - 0.25%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
Peptides (acetyl hexapeptide-8 0.20% - 0.40%, palmitoyl oligopeptide 0.30% - 0.50%, acetyl hexapeptide-8 0.10% - 0.25% and palmitoyl oligopeptide 0.20% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Humectants (acetyl hexapeptide-8 0.20% - 0.40%, alcaligenes polysaccharides 0.20% - 0.35%, sucrose 0.15% - 0.30%, glycerin 0.20% - 0.35%, saccharomyces lysate extract 0.15% - 0.25%, faex 0.10% - 0.25%, algae extract 0.20% - 0.35%, acetyl hexapeptide-8 0.10% - 0.25%, alcaligenes polysaccharides 0.15% - 0.30%, sucrose 0.10% - 0.20%, glycerin 0.15% - 0.30%, saccharomyces lysate extract 0.25% - 0.45%, faex 0.40% - 0.65% and algae extract 6.10% - 7.50%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 33.20$ up to 500.00$ in the United States and from 24.00£ up to 365.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 57 studies and safety reviews.

1
Dimethicone as a protective ingredient in topical medicationsjaad.org
2
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
3
Public Report: 2-Butenedioic acid (2E)-, di-C12-15-alkyl esters (INCI Name: Di-C12-15 Alkyl Fumarate)nicnas.gov.au
4
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
5
Amended Safety Assessment of Triglycerides as Used in Cosmeticir-safety.org
6
The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transferncbi.nlm.nih.gov
7
Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitaminsresearchgate.net
8
Purified Pland Extractskalidees.com
9
Nuclear Factor Kappa B Inhibition as a Therapeutic Target of Nutraceuticals in Arthritis, Osteoarthritis, and Related Inflammationsciencedirect.com
10
Resveratrol as an active ingredient for cosmetic and dermatological applications: a reviewncbi.nlm.nih.gov
11
Use of Probiotics for Dermal Applicationsresearchgate.net
12
Protein and oil composition of sesame seeds (Sesamum indicum, L.) grown in the Gizan area of Saudi Arabiatandfonline.com
13
Triglyceride composition of Sesamum indicum seed oilonlinelibrary.wiley.com
14
Seed oil content and fatty acid composition in East African sesame (Sesamum indicum L.) accessions evaluated over 3 yearssciencedirect.com
15
Antioxidant Activity and Cytotoxicity of Medicago sativa L. Seeds and Herb Extract on Skin Cellsncbi.nlm.nih.gov
16
Safety Assessment of Helianthus annuus (Sunflower)-Derived Ingredients as Used in Cosmeticscir-safety.org
17
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
18
Zinc salts in dermatologyncbi.nlm.nih.gov
19
An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disordersoatext.com
20
Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrinsncbi.nlm.nih.gov
21
Evaluation of the effects of topical zinc gluconate in wound healingncbi.nlm.nih.gov
22
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
23
Importance of the form of topical vitamin E for prevention of photocarcinogenesispubmed.ncbi.nlm.nih.gov
24
Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics cir-safety.org
25
The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healingncbi.nlm.nih.gov
26
Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Updatecore.ac.uk
27
Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gelpubmed.ncbi.nlm.nih.gov
28
Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmeticsjournals.sagepub.com
29
Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responsesliebertpub.com
30
Final Report on the Safety Assessment of Laureths 4 and 23journals.sagepub.com
31
TOPICAL COMPOSITIONS CONTAINING WHEY PROTEINS patentimages.storage.googleapis.com
32
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