Cortizone 10 Intensive Healing Anti Itch Creme

Cortizone 10 Intensive Healing Anti Itch Creme

Efficacy100/100IrritancyHigh
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Works for

1 of 1 advertised claim delivered

Moisturizing
13 ingredients credited for this claim
Strong support
What the product description says
“Maximum Strength Cortizone 10 Intensive Healing formula also contains seven moisturizers and vitamins A, C and E for soothing moisture that lasts all day.”
Source: Walgreens

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed collagen.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, hydrolyzed collagen.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: petrolatum

Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~2.4–2.9%
PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~3.1–3.8%
Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.2–0.35%
Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.3–0.55%
Hydrolyzed jojoba estersKey activeEffect: HighHelps soften the upper layer of the skin~0.25–0.45%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.2–5.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.6–5.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1–1.3%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.9–2.4%
Methyl gluceth-20Key active· HumectantEffect: MediumHelps attract water to the upper layer of the skin and soften it~0.4–0.65%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.4–0.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.5%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.6–1.9%

Can it cause trouble?

Irritancy
3 strong irritants: Menthyl lactate, Diazolidinyl urea + 1 more — patch-test recommended
High risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.4–0.6%est.
Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.35–0.65%est.
Menthyl lactateUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.
Diazolidinyl ureaA preservative. Works by releasing formaldehyde. Can be irritatingHigh~0.1–0.2%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.15%est.
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.05%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~2.4–2.9%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~1.6–1.9%est.
Steareth-21Helps oil and water mix togetherMedium~0.75–1.1%est.
Steareth-2Helps oil and water mix togetherMedium~0.55–0.85%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.5–0.8%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.35–0.6%est.
Magnesium ascorbyl phosphateA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very highMedium~0.3–0.55%est.
EdtaHelp to stabilize the product formulationMedium~0.2–0.4%est.
Potassium hydroxideUsed to adjust the pH level of productsMedium~0.2–0.4%est.
BhtA preservativeMedium~0.1–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1–1.3%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.6–5.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~4.2–5.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Petrolatum~3.1–3.8%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Jojoba esters~2.4–2.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Cetyl alcohol~1.9–2.4%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Aloe barbadensis leaf juice~1.6–1.9%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialReduces irritationReduces rednessAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Stearyl alcohol~1.5–1.8%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Distearyldimonium chloride~1.2–1.4%
Formula
Cetearyl alcohol~1–1.3%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Steareth-21~0.75–1.1%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-21
Steareth-2~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-2
Polysorbate 60~0.5–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Stearamidopropyl pg-dimonium chloride phosphate~0.45–0.7%
Formula
Methyl gluceth-20~0.4–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and soften it

More about Methyl gluceth-20
Propylene glycol~0.4–0.6%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Chamomilla recutita flower extract~0.35–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract
Tocopheryl acetate~0.35–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Magnesium ascorbyl phosphate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-agingAnti-oxidation

A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high

More about Magnesium ascorbyl phosphate
Hydrolyzed collagen~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen
Hydrolyzed elastin~0.3–0.55%
Formula
Hydrolyzed jojoba esters~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Hydrolyzed jojoba esters
Glyceryl stearate~0.3–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Edta~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Help to stabilize the product formulation

More about Edta
Ppg-12/smdi copolymer~0.25–0.5%
Formula
Irritation risk
Low

Used to create a nice product finish

More about Ppg-12/smdi copolymer
Potassium hydroxide~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to adjust the pH level of products

More about Potassium hydroxide
Beta-glucan~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationMoisturizingAnti-oxidationAnti-agingAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan
Menthyl lactate~0.2–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Menthyl lactate
Diazolidinyl urea~0.1–0.2%
Irritant · high
Irritation risk
High

A preservative. Works by releasing formaldehyde. Can be irritating

More about Diazolidinyl urea
Benzyl alcohol~0.1–0.15%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Methylparaben~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Bht~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Propylparaben~0.1–0.15%
Formula
Irritation risk
Low

A preservative

More about Propylparaben
Retinyl palmitate~0.05%
Irritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Ingredient list view

Water, Glycerin, Dimethicone, Petrolatum, Jojoba esters, Cetyl alcohol, Aloe barbadensis leaf juice, Stearyl alcohol, Distearyldimonium chloride, Cetearyl alcohol, Steareth-21, Steareth-2, Polysorbate 60, Stearamidopropyl pg-dimonium chloride phosphate, Methyl gluceth-20, Propylene glycol, Chamomilla recutita flower extract, Tocopheryl acetate, Magnesium ascorbyl phosphate, Hydrolyzed collagen, Hydrolyzed elastin, Hydrolyzed jojoba esters, Glyceryl stearate, Edta, Ppg-12/smdi copolymer, Potassium hydroxide, Beta-glucan, Menthyl lactate, Diazolidinyl urea, Benzyl alcohol, Methylparaben, Bht, Propylparaben, Retinyl palmitate

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Walgreens
$10.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Cortizone 10Intensive Healing Anti Itch CremeYOUR PRODUCTGold BondCracked Skin Relief Hand And Body LotionsGold Bond UltimateMen's Essentials Everyday LotionUp&UpExtra Repair Lotion
Match—57%56%50%
Price$10.99$5.99−$5.00$12.49+$1.50$1.99−$9.00
Shared key ingredients—6 of 75 of 75 of 7
Key difference—3-O-Ethyl Ascorbic AcidNiacinamideHydroxyethyl Urea
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"Cortizone 10 - Intensive Healing Anti Itch Creme" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Cortizone 10 - Intensive Healing Anti Itch Creme ticks this box. Glycerin, hydrolyzed collagen, methyl gluceth-20 and propylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (petrolatum, hydrolyzed collagen, jojoba esters, dimethicone and cetearyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer includes a form of Retinoids (vitamin A) - retinyl palmitate 0.05% - 0.05%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.

Irritation risk

We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 10.99$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
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  4. 4
  5. 5
  6. 6
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
Cortizone 10 Intensive Healing Anti Itch Creme
Cortizone 10Intensive Healing Anti Itch Creme

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