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Clinique Smart Night™ Custom-Repair Moisturizer
Clinique

Clinique Smart Night™ Custom-Repair Moisturizer

Efficacy87/100IrritancyMedium
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Works for

3 of 4 advertised claims delivered

Moisturizing
25 ingredients credited for this claim
Strong support
What the product description says
“Smart Night™ Custom-Repair Moisturizer”
Source: Clinique

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, algae extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.45–0.65%
Astrocaryum murumuru seed butterKey active· EmollientEffect: HighHelps soften the upper layer of the skin. Could be comedogenic due to the myrisic acid content~0.3–0.5%
Saccharomyces ferment filtrateKey active· HumectantEffect: HighA product of yeast fermentation. Helps attract water to the upper layer of the skin~0.3–0.55%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.7–2.1%
Soy amino acidsKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.25–0.45%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Micrococcus lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.25–0.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.9%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.3–0.55%
Hydrolyzed soy proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.35–0.65%
Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.7%
Isostearyl neopentanoate· EmollientEffect: LowUsed to create a nice product texture and helps soften the upper layer of the skin. Could be comedogenic~4.6–5.6%
Whey protein· EmollientEffect: LowA protein derived from milk. In skincare products, might help to soften the upper layer of the skin~0.45–0.7%
BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.95–1.15%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.1–3.7%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.4–2.9%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.55–0.8%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%
Yeast extractUnder-dosedEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.25–0.45%
PetrolatumUnder-dosedEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.3–0.55%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.55%
Evens skin tone
6 ingredients credited for this claim
Strong support
What the product description says
“Clinique Smart Night Custom-Repair Moisturizer works at night to help visibly repair the four major signs of aging: lines&wrinkles,loss of firmness/elasticity, dark spots/uneven skin tone and lack of radiance.”
Source: Ulta

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.7%
Hydrolyzed soy proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.35–0.65%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Yeast extractEffect: Low, below effective doseHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.25–0.45%
Anti-aging
6 ingredients credited for this claim
Strong support
What the product description says
“What It Is Our smart nighttime moisturizer targets all major signs of aging.”
Source: Clinique

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.7%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%
Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.45–0.65%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Exfoliation
1 ingredient credited for this claim
Limited support
What the product description says
“This formula uses multi-level exfoliation to reveal newer, brighter skin by the next morning.”
Source: Ulta

This product might help exfoliate the skin with acetyl glucosamine, but This ingredient is not the most effective.

Acetyl glucosamineKey activeEffect: MediumAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Anti-oxidation
Not advertised by the brand · 10 ingredients credited for this claim
Moderate support

This product contains antioxidants (camellia sinensis leaf extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%
CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.45–0.7%
Micrococcus lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.25–0.5%
Hydrolyzed soy proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.35–0.65%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.7%
Centaurium erythraea extractEffect: LowA plant extract that can help calm down inflammation in skin~0.55–0.85%
ErgothioneineUnder-dosedEffect: HighCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.7–1.05%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Yeast extractUnder-dosedEffect: MediumHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.25–0.45%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.5%

Can it cause trouble?

Irritancy
14 flagged ingredients
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Isostearyl neopentanoateUsed to create a nice product texture and helps soften the upper layer of the skin. Could be comedogenicMedium~4.6–5.6%est.
Centaurium erythraea extractA plant extract that can help calm down inflammation in skinMedium~0.55–0.85%est.
Sigesbeckia orientalis extractA plant extract that can contain an anti-inflammatory compoundMedium~0.5–0.7%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.45–0.7%est.
Astrocaryum murumuru seed butterHelps soften the upper layer of the skin. Could be comedogenic due to the myrisic acid contentMedium~0.3–0.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.5%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.25–0.45%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.
Aminopropyl ascorbyl phosphateA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)Medium~0.15–0.3%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.15–0.25%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.15–0.25%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.1%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~0.45–0.65%est.
Isostearyl neopentanoateUsed to create a nice product texture and helps soften the upper layer of the skin. Could be comedogenic2/5~4.6–5.6%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.5–1.9%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Isostearyl neopentanoate~4.6–5.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

Used to create a nice product texture and helps soften the upper layer of the skin. Could be comedogenic

More about Isostearyl neopentanoate
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~3.1–3.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Glyceryl stearate~2.4–2.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~2–2.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Dimethicone~1.7–2.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Cetearyl alcohol~1.5–1.9%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Tamarindus indica seed extract~1.2–1.5%
Formula
Irritation risk
Low
More about Tamarindus indica seed extract
Biotin~0.95–1.15%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Ergothioneine~0.7–1.05%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Centaurium erythraea extract~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

A plant extract that can help calm down inflammation in skin

More about Centaurium erythraea extract
Sigesbeckia orientalis extract~0.5–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatory

A plant extract that can contain an anti-inflammatory compound

More about Sigesbeckia orientalis extract
Caffeine~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Whey protein~0.45–0.7%
Formula
Irritation risk
Low
Works for
Moisturizing

A protein derived from milk. In skincare products, might help to soften the upper layer of the skin

More about Whey protein
Glycine soja protein~0.45–0.7%
Key active
Irritation risk
Low
Works for
CleansingMoisturizingEvens skin toneAnti-agingAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein
Isohexadecane~0.55–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Hydrolyzed soy protein~0.35–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-oxidationAnti-inflammatory

Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing

More about Hydrolyzed soy protein
Algae extract~0.45–0.65%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract
Saccharomyces ferment filtrate~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A product of yeast fermentation. Helps attract water to the upper layer of the skin

More about Saccharomyces ferment filtrate
Acetyl hexapeptide-8~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Micrococcus lysate~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatory

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"

More about Micrococcus lysate
Lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Yeast extract~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatoryAnti-oxidationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract
Soy amino acids~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Help attract water to the upper layer of the skin

More about Soy amino acids
Camellia sinensis leaf extract~0.25–0.5%
Key active
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Astrocaryum murumuru seed butter~0.3–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin. Could be comedogenic due to the myrisic acid content

More about Astrocaryum murumuru seed butter
Glycereth-26~0.25–0.45%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Cetyl alcohol~0.3–0.55%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Tocopheryl acetate~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Acetyl glucosamine~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Evens skin toneMoisturizingAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Petrolatum~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.25–0.45%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Cetearyl glucoside~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Acrylates/c10-30 alkyl acrylate crosspolymer~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Sodium benzoate~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Tromethamine~0.2–0.4%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Citric acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Polysorbate 80~0.25–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Aminopropyl ascorbyl phosphate~0.15–0.3%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingEvens skin toneAnti-oxidation

A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)

More about Aminopropyl ascorbyl phosphate
Hexylene glycol~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Hydroxyethylcellulose~0.15–0.3%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Sodium citrate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Disodium edta~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Isostearyl neopentanoate, Glycerin, Butylene glycol, Glyceryl stearate, Peg-100 stearate, Dimethicone, Cetearyl alcohol, Tamarindus indica seed extract, Biotin, Ergothioneine, Centaurium erythraea extract, Sigesbeckia orientalis extract, Caffeine, Whey protein, Glycine soja protein, Isohexadecane, Hydrolyzed soy protein, Algae extract, Saccharomyces ferment filtrate, Acetyl hexapeptide-8, Micrococcus lysate, Lecithin, Yeast extract, Soy amino acids, Camellia sinensis leaf extract, Astrocaryum murumuru seed butter, Glycereth-26, Cetyl alcohol, Tocopheryl acetate, Acetyl glucosamine, Petrolatum, Acrylamide/sodium acryloyldimethyltaurate copolymer, Cetearyl glucoside, Caprylyl glycol, Sodium hyaluronate, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium benzoate, Tromethamine, Citric acid, Polysorbate 80, Aminopropyl ascorbyl phosphate, Hexylene glycol, Hydroxyethylcellulose, Sodium citrate, Disodium edta, Phenoxyethanol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CliniqueSmart Night™ Custom-Repair MoisturizerYOUR PRODUCTEstée LauderRe-Nutriv Ultimate Lift Regenerating Youth Moisturizer Creme RichTom FordResearch CrèmeDarphinIdeal Resource Anti-Age & Radiance Eye Contour Radiance Repair Cream
Match—59%58%50%
Price$43.40$350.00+$306.60$244.44+$201.04$53.15+$9.75
Shared key ingredients—10 of 1711 of 178 of 17
Key difference—Linoleic AcidSalicylic AcidKnotgrass Extract
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"Clinique - Smart Night™ Custom-Repair Moisturizer" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Clinique - Smart Night™ Custom-Repair Moisturizer ticks this box. Acetyl glucosamine, acetyl hexapeptide-8, faex, glycerin and saccharomyces ferment filtrate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Astrocaryum murumuru seed butter, dimethicone, cetearyl alcohol, cetyl alcohol and glycine soja protein in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.30% - 0.55%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 39.89$ up to 65.00$ in the United States, for 90.74CA$ in Canada and for 111.00A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

  1. 1
    Amended Safety Assessment of Alkyl Esters as Used in Cosmeticscir-safety.org
  2. 2
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  3. 3
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  4. 4
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  5. 5
    A comparison of the relative antioxidant potency of L‐ergothioneine and idebenoneonlinelibrary.wiley.com
  6. 6
    l-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Studymdpi.com
Clinique Smart Night™ Custom-Repair Moisturizer
CliniqueSmart Night™ Custom-Repair Moisturizer
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