Clinique - Smart Night™ Clinical MD Multi-Dimensional Repair Treatment Retinol

Clinique Smart Night™ Clinical MD Multi-Dimensional Repair Treatment Retinol

Efficacy100/100

Works for:

based on ingredients and %
  • Anti-aging
  • Moisturizing
  • Evens skin tone
  • Anti-oxidation

Can it cause trouble?

  • Irritation risk: medium
  • Comedogenic risk ingredients: 2

Key actives

Niacinamide2% - 2.4%Retinol0.5% - 0.75%Tocopherol0.3% - 0.5%
USD79.00
Price as of Jun 7, 2026.
Amazon US
Lowest price
Buy from Amazon US — USD79.00

Product Summary

"Clinique - Smart Night™ Clinical MD Multi-Dimensional Repair Treatment Retinol" is effective for: Anti-aging, Moisturizing, Anti-blemish, Evens skin tone and Exfoliation

Ingredient callouts

  • A good concentration of Niacinamide (2.00% - 2.40%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.35% - 0.65%) it cannot have a noticeable benefit for the skin.
  • This product contains an effective form of Retinoids (vitamin A): retinol 0.50% - 0.75%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
  • Peptides (acetyl hexapeptide-8 0.25% - 0.50%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Humectants (hydroxyethyl urea 0.70% - 1.05%, urea 0.30% - 0.60%, trehalose 0.30% - 0.50%, sodium pca 0.25% - 0.50%, sodium hyaluronate 0.45% - 0.65%, glycerin 2.50% - 3.00%, algae extract 1.30% - 1.60% and acetyl hexapeptide-8 0.25% - 0.50%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 73.00$ up to 79.00$ in the United States and for 90.00CA$ in Canada.

For a detailed price comparison: click here.

USD79.00
Amazon US Lowest price