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Clinicians Complex Retinol Eye Cream
Clinicians Complex

Clinicians Complex Retinol Eye Cream

Efficacy87/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Anti-aging
4 ingredients credited for this claim
Strong support
What the product description says
“Retinol, Coenzyme Q10 and Vitamin E combine with a cocktail of naturally moisturizing oils and extracts to intensely hydrate and rejuvenate fragile skin around the eyes.”
Source: Skinstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: retinyl palmitate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~3.5–5.3%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.95–1.45%
Moisturizing
17 ingredients credited for this claim
Good support
What the product description says
“After use, eyes look smoother and brighter with restored hydration.”
Source: Skinstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: cyclomethicone, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, dimethiconol.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.6%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.5–2.2%
Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.4–0.95%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.35–0.85%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~0.15–0.5%
CyclomethiconeKey active· Humectant, EmollientEffect: HighA type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer~0.85–1.3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.1–0.3%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.55–1.25%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.4%
Ethylhexyl cocoateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.45–1.1%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.35–0.8%
Cetyl estersKey active· EmollientEffect: MediumHelps soften upper layer of the skin and can enhance penetration of other ingredients into the upper layer of the skin~0.35–0.85%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~2–3%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~3.7–5.5%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.15–0.6%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.4–0.95%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.95–1.45%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (retinol, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.4%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~1.2–1.8%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.95–1.45%
Evens skin tone
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: retinyl palmitate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~3.5–5.3%
Exfoliation
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Retinyl palmitateEffect: LowThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~3.5–5.3%

Can it cause trouble?

Irritancy
3 strong irritants: Retinyl palmitate, Retinol + 1 more — patch-test recommended
High risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~3.5–5.3%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~2.7–4%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.15–0.6%est.
Citrus grandis seed extract—High~0.01–0.05%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~1.2–1.8%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.4–0.95%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.05–0.3%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~0.15–0.5%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~2–3%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.4–0.95%est.
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Cheaper Alternatives
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Retinol Eye Cream with Squalane + Ceramides
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Phospholipids~3.7–5.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Retinyl palmitate~3.5–5.3%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Retinol~2.7–4%
Hero · Anti-aging, Evens skin toneIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Glyceryl stearate se~2–3%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Glycerin~1.8–2.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Squalane~1.5–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Tocopheryl acetate~1.2–1.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Tocopherol~0.95–1.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Cyclomethicone~0.85–1.3%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer

More about Cyclomethicone
Dimethiconol~0.55–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Ethylhexyl cocoate~0.45–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl cocoate
Glycine soja oil~0.4–0.95%
Key activeComedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Lecithin~0.4–0.95%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Glycolipids~0.35–0.8%
Formula
Irritation risk
Low
More about Glycolipids
Cetyl esters~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften upper layer of the skin and can enhance penetration of other ingredients into the upper layer of the skin

More about Cetyl esters
Wax, hybrid
Not recognized
Helianthus annuus seed oil~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Emulsifying wax n.f
Not recognized
Cetyl alcohol~0.35–0.8%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Propylene glycol~0.15–0.6%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Dimonium
Not recognized
Potassium chloride~0.15–0.5%
Formula
Irritation risk
Low
More about Potassium chloride
Isopropyl myristate~0.15–0.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Ubiquinone~0.1–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Triethanolamine~0.05–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Polysorbate 20~0.05–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Dimethicone~0.1–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Carbomer~0.05–0.1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Citrus grandis seed extract~0.01–0.05%
Irritant · high
Irritation risk
High
More about Citrus grandis seed extract
Ingredient list view

Water, Phospholipids, Retinyl palmitate, Retinol, Glyceryl stearate se, Glycerin, Squalane, Tocopheryl acetate, Tocopherol, Cyclomethicone, Dimethiconol, Ethylhexyl cocoate, Glycine soja oil, Lecithin, Glycolipids, Cetyl esters, Unknown, Helianthus annuus seed oil, Unknown, Cetyl alcohol, Propylene glycol, Unknown, Potassium chloride, Isopropyl myristate, Ubiquinone, Triethanolamine, Polysorbate 20, Dimethicone, Carbomer, Citrus grandis seed extract

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Clinicians ComplexRetinol Eye CreamYOUR PRODUCTFirst Aid BeautyRetinol Eye Cream with Squalane + CeramidesBeauty PieSuper Retinol Anti-wrinkle Eye CreamSuper RetinolAnti-wrinkle Eye Cream
Match—89%87%87%
Price$55.00$21.80−$33.20$33.05−$21.95$17.19−$37.81
Shared key ingredients—6 of 127 of 127 of 12
Key difference—Ceramide NgSodium HyaluronateSodium Hyaluronate
Irritancy High Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
    Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
  2. 2
    Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
  3. 3
    A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
  4. 4
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  5. 5
    Vitamin E in dermatologyncbi.nlm.nih.gov
  6. 6
    Vitamin E and Skin Healthlpi.oregonstate.edu
Clinicians Complex Retinol Eye Cream
Clinicians ComplexRetinol Eye Cream
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As an Amazon Associate, WIMJ earns from qualifying purchases.