Centellian24

Centellian24 Madeca Cream Active Skin Formula

Name: Centellian24 - Madeca Cream Active Skin Formula
Brand: Centellian24

Efficacy100/100IrritancyHigh

See all ingredients In 1 routines

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Works for

3 of 3 advertised claims delivered

Evens skin tone

Niacinamide

Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.1–1.4%

Moisturizing

Ceramide np, Niacinamide + 28 more

Strong evidence

What the product description says

“EXCEPTIONAL ABSORPTION & COMFORT , Enjoy a non-greasy and highly absorbent moisturizing experience with Centellian 24 Madeca Cream.”

Source: Amazon US

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: carnosine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, panthenol

BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.45–0.7%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.5–3%

CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

Soluble collagenKey active· HumectantEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.25–0.45%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.25–0.5%

Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.2–0.4%

AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.1–3.8%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%

Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.3–0.55%

Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.5%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.1–1.4%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.55–0.8%

GlycoproteinsKey activeEffect: High~0.2–0.4%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.4%

Ricinus communis seed oilKey active· Emollient, OcclusiveEffect: HighA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency~0.25–0.45%

Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.25–0.5%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1–1.3%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.25–0.5%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.4%

Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~1.7–2.1%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–1.8%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~4.1–5.1%

Pentaerythrityl tetraethylhexanoate· EmollientEffect: LowUsed to create a nice product consistency while softening the upper layer of the skin~2–2.4%

Polyglyceryl-6 distearateEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.65–1%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.45%

Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~0.5–0.75%

Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.25%

Anti-aging

Adenosine, Niacinamide + 5 more

Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, carnosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.5%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.4%

Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%

Anti-blemish

Not advertised by the brand · Niacinamide, Lauric acid + 1 more

Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Lauric acidEffect: LowHelps water and oil mix together. Has anti-bacterial properties that might be helpful in preventing blemishes~0.3–0.55%

Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%

Anti-oxidation

Not advertised by the brand · Carnosine, Asiaticoside + 5 more

Strong evidence

This product contains antioxidants (asiaticoside, carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - tocopheryl linoleate also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

Tocopheryl linoleateKey activeEffect: MediumA relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient~0.2–0.4%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

Pelargonium graveolens flower oilEffect: LowAn essential oil. Can be irritating. Can become an allergen with oxidation~0.25–0.45%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.25%

Can it cause trouble?

Irritancy

8 strong irritants: Pelargonium graveolens flower oil, Citrus paradisi peel oil + 6 more — patch-test recommended

High risk

We flagged 33 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.25–0.45%est.

Citrus paradisi peel oilUsed as a fragrance. Can be irritatingHigh~0.2–0.4%est.

Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.2–0.4%est.

Copaifera officinalis resinUsed as a fragranceHigh~0.25–0.45%est.

Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.2–0.4%est.

Vanilla planifolia fruit extractA plant extract used as a fragrance. Can be irritatingHigh~0.2–0.35%est.

Citrus aurantium dulcis flower oil—High~0.15–0.3%est.

Chamomilla recutita flower oilPlant oil that can have healing and anti-inflammatory properties. It contains volatile compouunds that are potential allergens and can be irritatingHigh~0.15–0.3%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.5–3%est.

Polyglyceryl-6 distearateHelps oil and water mix together while softening the upper layer of the skinMedium~0.65–1%est.

Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.45–0.65%est.

1,2-hexanediolA preservativeMedium~0.4–0.6%est.

Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.45–0.7%est.

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.35–0.6%est.

AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.25–0.5%est.

Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.25–0.5%est.

Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.3–0.55%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.25–0.5%est.

Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.2–0.4%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.45%est.

Polyglyceryl-3 beeswaxHelps water and oil mix together. Could be an allergen (beeswax)Medium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.25–0.45%est.

Disodium edtaStabilizes the product formulationMedium~0.25–0.4%est.

Polysorbate 60Helps oil and water mix togetherMedium~0.25–0.45%est.

Ricinus communis seed oilA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistencyMedium~0.25–0.45%est.

MethylpropanediolHelps dissolve other ingredients in a formulationMedium~0.25–0.45%est.

Juniperus virginiana oilCedarwood oil. Used as a fragrance. Can be irritatingMedium~0.2–0.4%est.

Lauric acidHelps water and oil mix together. Has anti-bacterial properties that might be helpful in preventing blemishesMedium~0.3–0.55%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.25–0.5%est.

Hydrogenated phosphatidylcholineHelps oil and water mix togetherMedium~0.25–0.45%est.

Isostearyl isostearateHelps soften the upper layer of the skin and improve the product texture. It can be comedogenicMedium~0.25–0.45%est.

Tocopheryl linoleateA relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredientMedium~0.2–0.4%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.2–0.35%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Lauric acidHelps water and oil mix together. Has anti-bacterial properties that might be helpful in preventing blemishes3/5~0.3–0.55%est.

Isostearyl isostearateHelps soften the upper layer of the skin and improve the product texture. It can be comedogenic3/5~0.25–0.45%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1–1.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Dipropylene glycol~6.6–8.1%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Hydrogenated polydecene~4.1–5.1%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Glycerin~3.1–3.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Caprylic/capric triglyceride~2.5–3%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Pentaerythrityl tetraethylhexanoate~2–2.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product consistency while softening the upper layer of the skin

More about Pentaerythrityl tetraethylhexanoate

Cyclohexasiloxane~1.7–2.1%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

Glyceryl stearate~1.5–1.8%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Niacinamide~1.1–1.4%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Cetearyl alcohol~1–1.3%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Polyglyceryl-6 distearate~0.65–1%

Irritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Polyglyceryl-6 distearate

Panthenol~0.55–0.8%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Dicaprylyl ether~0.5–0.75%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether

Polyglyceryl-10 laurate~0.45–0.65%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate

1,2-hexanediol~0.4–0.6%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Sodium stearoyl glutamate~0.45–0.7%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate

Beeswax~0.45–0.7%

Key active

Irritation risk: Low

Works for

Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.35–0.6%

Irritant · medium

Irritation risk: Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer

Asiaticoside~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside

Madecassic acid~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid

Jojoba esters~0.3–0.55%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters

Olea europaea fruit oil~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Asiatic acid~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryReduces irritationMoisturizing

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid

Butylene glycol~0.25–0.45%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Hydroxyacetophenone~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Polyglyceryl-3 beeswax~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together. Could be an allergen (beeswax)

More about Polyglyceryl-3 beeswax

Cetyl alcohol~0.25–0.5%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol

Ethylhexylglycerin~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Centella asiatica oil~0.2–0.35%

Formula

Irritation risk: Low

More about Centella asiatica oil

Xanthan gum~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Soluble collagen~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Soluble collagen

Adenosine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Pelargonium graveolens flower oil~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil

Disodium edta~0.25–0.4%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Citrus paradisi peel oil~0.2–0.4%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Citrus paradisi peel oil

Citrus aurantium dulcis peel oil~0.2–0.4%

Irritant · high

Irritation risk: High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil

Polysorbate 60~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 60

Sorbitan isostearate~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Ricinus communis seed oil~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-inflammatory

A plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency

More about Ricinus communis seed oil

Methylpropanediol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol

Sodium laurate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sodium laurate

Carnosine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine

Juniperus virginiana oil~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Cedarwood oil. Used as a fragrance. Can be irritating

More about Juniperus virginiana oil

Copaifera officinalis resin~0.25–0.45%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Copaifera officinalis resin

Ceramide np~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Lavandula angustifolia oil~0.2–0.4%

Irritant · high

Irritation risk: High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil

Hyaluronic acid~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Phospholipids~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Elastin~0.2–0.4%

Formula

Irritation risk: Low

More about Elastin

Lauric acid~0.3–0.55%

Comedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

CleansingAnti-blemishAntibacterial

Helps water and oil mix together. Has anti-bacterial properties that might be helpful in preventing blemishes

More about Lauric acid

Glycoproteins~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Glycoproteins

Centella asiatica extract~0.25–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Reduces rednessReduces irritationMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Hydrogenated phosphatidylcholine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Hydrogenated phosphatidylcholine

Isostearyl isostearate~0.25–0.45%

Comedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Helps soften the upper layer of the skin and improve the product texture. It can be comedogenic

More about Isostearyl isostearate

Tocopheryl linoleate~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient

More about Tocopheryl linoleate

Cholesterol~0.25–0.5%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Inulin lauryl carbamate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

More about Inulin lauryl carbamate

Vanilla planifolia fruit extract~0.2–0.35%

Irritant · high

Irritation risk: High

A plant extract used as a fragrance. Can be irritating

More about Vanilla planifolia fruit extract

Viola odorata leaf extract~0.2–0.35%

Formula

Irritation risk: Low

More about Viola odorata leaf extract

Citrus aurantium dulcis flower oil~0.15–0.3%

Irritant · high

Irritation risk: High

More about Citrus aurantium dulcis flower oil

Chamomilla recutita flower oil~0.15–0.3%

Irritant · high

Irritation risk: High

Plant oil that can have healing and anti-inflammatory properties. It contains volatile compouunds that are potential allergens and can be irritating

More about Chamomilla recutita flower oil

Potassium cetyl phosphate~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Tromethamine~0.15–0.3%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Tetrahydropiperine~0.1–0.25%

Formula

Irritation risk: Low

More about Tetrahydropiperine

Tocopherol~0.1–0.25%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Ingredient list view

Water, Dipropylene glycol, Hydrogenated polydecene, Glycerin, Caprylic/capric triglyceride, Pentaerythrityl tetraethylhexanoate, Cyclohexasiloxane, Glyceryl stearate, Niacinamide, Cetearyl alcohol, Polyglyceryl-6 distearate, Panthenol, Dicaprylyl ether, Polyglyceryl-10 laurate, 1,2-hexanediol, Sodium stearoyl glutamate, Beeswax, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Asiaticoside, Madecassic acid, Jojoba esters, Olea europaea fruit oil, Asiatic acid, Butylene glycol, Hydroxyacetophenone, Polyglyceryl-3 beeswax, Cetyl alcohol, Ethylhexylglycerin, Centella asiatica oil, Xanthan gum, Soluble collagen, Adenosine, Pelargonium graveolens flower oil, Disodium edta, Citrus paradisi peel oil, Citrus aurantium dulcis peel oil, Polysorbate 60, Sorbitan isostearate, Ricinus communis seed oil, Methylpropanediol, Sodium laurate, Carnosine, Juniperus virginiana oil, Copaifera officinalis resin, Ceramide np, Lavandula angustifolia oil, Hyaluronic acid, Phospholipids, Elastin, Lauric acid, Glycoproteins, Centella asiatica extract, Hydrogenated phosphatidylcholine, Isostearyl isostearate, Tocopheryl linoleate, Cholesterol, Inulin lauryl carbamate, Vanilla planifolia fruit extract, Viola odorata leaf extract, Citrus aurantium dulcis flower oil, Chamomilla recutita flower oil, Potassium cetyl phosphate, Tromethamine, Tetrahydropiperine, Tocopherol

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Amazon USPrice as of 10/30/2026 06:54 GMT

$24.99

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Centellian24Madeca Cream Active Skin FormulaYOUR PRODUCT	TOSOWOONGJeju Mayu Cream	NekerMoistouch Centellayer Cream	mixsoonCica Hyal Deep Soothing Cream 50ml
Match	—	94%	90%	89%
Price	$24.99	$22.33−$2.66	$17.60−$7.39	$14.01−$10.98
Shared key ingredients	—	12 of 19	12 of 19	11 of 19
Key difference	—	Oligopeptide-1	Madecassoside	Bacillus Ferment
Irritancy	High	Medium	High	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Judging from the ingredient list, "Centellian24 - Madeca Cream Active Skin Formula" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Centellian24 - Madeca Cream Active Skin Formula ticks this box. Humectants in this product (panthenol, carnosine, glycerin, hyaluronic acid and soluble collagen) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, cholesterol, jojoba esters, beeswax and caprylic/capric triglyceride) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

Another benefit is that this moisturizer contain ceramides (ceramide np 0.25% - 0.50%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Adenosine 0.20% - 0.40%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.20% - 0.40%, madecassic acid 0.25% - 0.50% and asiaticoside 0.25% - 0.50% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
An effective concentration of Panthenol (pro-vitamin B5) - about 0.55% - 0.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e and centella asiatica extract

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.