Avant Skincare R.N.A Radical Anti-Ageing & Lifting Duo Moisturiser

Avant Skincare R.N.A Radical Anti-Ageing & Lifting Duo Moisturiser

Efficacy50/100IrritancyMedium
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Works for

2 of 4 advertised claims delivered

Anti-aging
4 ingredients credited for this claim
Strong support
What the product description says
“R. N. A Radical Anti-Ageing & Lifting Duo Moisturiser”
From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains heptapeptide-15 palmitate.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: copper palmitoyl heptapeptide-14.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Heptapeptide-15 palmitateKey activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Copper palmitoyl heptapeptide-14Key activeEffect: MediumThe copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.~0.1–0.2%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.9–2.3%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.3–1.6%
Moisturizing
21 ingredients credited for this claim
Strong support
What the product description says
“R. N. A Radical Anti-Ageing & Lifting Duo Moisturiser”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: copper palmitoyl heptapeptide-14, heptapeptide-15 palmitate

Copper palmitoyl heptapeptide-14Hero· HumectantEffect: HighThe copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.~0.1–0.2%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.45–0.7%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.45–0.65%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~1.6–2%
Heptapeptide-15 palmitateHero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Histidine hclKey activeEffect: HighA salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function~0.55–0.8%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.75–1.1%
TyrosineKey activeEffect: High~0.5–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.5–0.75%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~1.3–1.5%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.9–2.3%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~1–1.3%
Dimethicone crosspolymerKey activeEffect: MediumUsed to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface~0.3–0.55%
Vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~8.4–10.3%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.45–0.7%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.2%
Isodecyl neopentanoate· Emollient, OcclusiveEffect: LowAn emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.~4–4.9%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.4–0.6%
Polyglyceryl-10 stearateEffect: LowHelps water and oil mix together and softens the upper layer of the skin~0.3–0.6%
Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.35–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.3–1.6%
Evens skin tone
No ingredient credited for this claim
No support
What the product description says
“Formulated using R. N. A, an anti-ageing superhero that not only targets lines but dark spots and sagging too, you’ll be treated to a firmer finish with a more even tone.”
Source: Beauty Expert

Effective ingredients missing or their concentration is too low

Exfoliation
No ingredient credited for this claim
No support
What the product description says
“Added Glycolic Acid also targets firmness while working on dullness as well for a brighter finish.”
Source: Beauty Expert

This product does not contain effective exfoliating ingredients. It might be able to deliver physical exfoliation, that is scrub off some of the dead cells on the surface of the skin. We do not recommend physical exfoliation, because it is not uniform (some bits of skin can get exfoliated too much while others not at all). It can also traumatize the skin and aggrevate acne and other skin conditions.

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~1.8–2.2%est.
PhenylpropanolHelps mask the smell of other ingredients and helps preserve the product formulationHigh~0.2–0.35%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~2.9–3.5%est.
Pyridoxine hclMight help neutralize free radicals in skinMedium~0.6–0.95%est.
Polyglyceryl-10 stearateHelps water and oil mix together and softens the upper layer of the skinMedium~0.3–0.6%est.
Polyvinyl alcoholHelps improve the product textureMedium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.2%est.
EthylhexylglycerinA preservativeMedium~0.05%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.9–2.3%est.
Hydrogenated cottonseed oil—3/5~0.55–0.8%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Vegetable oil~8.4–10.3%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Vegetable oil
Isodecyl neopentanoate~4–4.9%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.

More about Isodecyl neopentanoate
Sodium acrylates copolymer~2.9–3.5%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Parfum~1.8–2.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Butyrospermum parkii butter~1.9–2.3%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Helianthus annuus seed oil~1.6–2%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Tocopherol~1.3–1.6%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Arginine~1.3–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Phospholipids~1–1.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Mannitol~0.75–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Pyridoxine hcl~0.6–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl
Rna~0.55–0.85%
Formula
Irritation risk
Low
More about Rna
Histidine hcl~0.55–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

A salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function

More about Histidine hcl
Phenylalanine~0.5–0.8%
Formula
Irritation risk
Low
More about Phenylalanine
Tyrosine~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Hydrogenated cottonseed oil~0.55–0.8%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Hydrogenated cottonseed oil
Glycerin~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclopentasiloxane~0.45–0.7%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Dimethiconol~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Dimethicone~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Hydrogenated polyisobutene~0.4–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Polyglyceryl-10 stearate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps water and oil mix together and softens the upper layer of the skin

More about Polyglyceryl-10 stearate
Polyglyceryl-6 dioleate~0.35–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Polyglyceryl-6 dioleate
Dimethicone crosspolymer~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer
Disodium adenosine triphosphate~0.3–0.55%
Formula
Glyceryl caprylate~0.35–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Lactic acid/glycolic acid copolymer~0.25–0.45%
Formula
Polyvinyl alcohol~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Helps improve the product texture

More about Polyvinyl alcohol
Phenylpropanol~0.2–0.35%
Irritant · high
Irritation risk
High

Helps mask the smell of other ingredients and helps preserve the product formulation

More about Phenylpropanol
Heptapeptide-15 palmitate~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingMoisturizing

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Heptapeptide-15 palmitate
Copper palmitoyl heptapeptide-14~0.1–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

The copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.

More about Copper palmitoyl heptapeptide-14
Xanthan gum~0.1–0.15%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Caprylyl glycol~0.1–0.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.05%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Phenoxyethanol~0.05–0.1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Vegetable oil, Isodecyl neopentanoate, Sodium acrylates copolymer, Parfum, Butyrospermum parkii butter, Helianthus annuus seed oil, Tocopherol, Arginine, Phospholipids, Mannitol, Pyridoxine hcl, Rna, Histidine hcl, Phenylalanine, Tyrosine, Hydrogenated cottonseed oil, Glycerin, Cyclopentasiloxane, Dimethiconol, Dimethicone, Hydrogenated polyisobutene, Polyglyceryl-10 stearate, Polyglyceryl-6 dioleate, Dimethicone crosspolymer, Disodium adenosine triphosphate, Glyceryl caprylate, Lactic acid/glycolic acid copolymer, Polyvinyl alcohol, Phenylpropanol, Heptapeptide-15 palmitate, Copper palmitoyl heptapeptide-14, Xanthan gum, Caprylyl glycol, Ethylhexylglycerin, Phenoxyethanol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Avant SkincareR.N.A Radical Anti-Ageing & Lifting Duo MoisturiserYOUR PRODUCTACURERadically Rejuvenating Whipped Night CreamTulaFirming & Hydrating Face MoisturizerDrunk ElephantProtini Polypeptide Cream
Match—52%51%51%
Price$108.08$20.00−$88.08$64.00−$44.08$22.00−$86.08
Shared key ingredients—3 of 135 of 134 of 13
Key difference—Salicylic AcidNiacinamideSh-Polypeptide-9
Irritancy Medium Low Medium Medium
Drying alcohol————
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Product summary

Judging from the ingredient list, "Avant Skincare - R. N. A Radical Anti-Ageing & Lifting Duo Moisturiser" works well for improving skin hydration This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Copper palmitoyl heptapeptide-14, heptapeptide-15 palmitate, arginine, glycerin and mannitol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (arginine, butyrospermum parkii butter, dimethicone, dimethiconol and helianthus annuus seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moistruizer also contains peptides (heptapeptide-15 palmitate 0.15% - 0.25% and copper palmitoyl heptapeptide-14 0.10% - 0.20%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 109.00$ in the United States and from 81.75£ up to 109.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
    Vitamin E in dermatologyncbi.nlm.nih.gov
Avant Skincare R.N.A Radical Anti-Ageing & Lifting Duo Moisturiser
Avant SkincareR.N.A Radical Anti-Ageing & Lifting Duo Moisturiser

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