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ALASTIN Skincare Regenerating Skin Nectar with TriHex+
ALASTIN Skincare

ALASTIN Skincare Regenerating Skin Nectar with TriHex+

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Palmitoyl hexapeptide-12, Palmitoyl tripeptide-1 + 2 more
Works well
What the product description says
“Helps strengthen skin barrier ahead of cosmetic treatments for visibly smoother, brighter, more youthful-looking skin afterward.”
Source: Alastin

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.8–2.7%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.6–2.4%
Panthenyl triacetateEffect: LowA stable oil-soluble derivative of vitamin B5. It can help support skin barrier and reduce inflammation in skin~2.6–3.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.7%
Moisturizing
Palmitoyl hexapeptide-12, Palmitoyl tripeptide-1 + 11 more
Works well
What the product description says
“Helps strengthen skin barrier ahead of cosmetic treatments for visibly smoother, brighter, more youthful-looking skin afterward.”
Source: Alastin

This product can help soften the skin and reduce its moisture loss with emollients and occlusives: dimethicone, squalane.

Keep in mind that this product does not contain effective ingredients to attract water to the upper layer of the skin. This is why an additional product with humectants like glycerin or hyaluronic acid can be helpful (apply it before this product for the best results).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl hexapeptide-12, palmitoyl tripeptide-1

Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.8–2.7%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.6–2.4%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~22–33%
Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~3.6–5.4%
Panthenyl triacetateKey activeEffect: HighA stable oil-soluble derivative of vitamin B5. It can help support skin barrier and reduce inflammation in skin~2.6–3.8%
NaringeninKey activeEffect: MediumA flavanoid that can be found in high concentrations in grapefruits, oranges, other citrus fruits, and tomato skin. Early studies suggest that it might be able to help reduce inflammation in skin and neutralize free radicals~1.1–1.7%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.45–1.1%
Dunaliella salina extractKey activeEffect: MediumA green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin~0.35–0.8%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.7%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~5–7.5%
Propylene carbonateEffect: LowIs used to dissolve other ingredients and create nice product texture~0.1–0.35%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.7%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.15–0.65%
Anti-oxidation
Side benefit · Naringenin, Olea europaea leaf extract + 2 more
May help

This product contains antioxidants (naringenin) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

NaringeninKey activeEffect: MediumA flavanoid that can be found in high concentrations in grapefruits, oranges, other citrus fruits, and tomato skin. Early studies suggest that it might be able to help reduce inflammation in skin and neutralize free radicals~1.1–1.7%
Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.9–1.35%
Dunaliella salina extractEffect: LowA green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin~0.35–0.8%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.7%

Can it cause trouble?

Irritancy
1 strong irritant: Arnica montana flower extract
Medium risk
We flagged 6 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.55–1.25%est.
Pentaerythrityl tetraisostearateUsed to create a thicker product consistencyMedium~3.2–4.9%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~3.6–5.4%est.
NaringeninA flavanoid that can be found in high concentrations in grapefruits, oranges, other citrus fruits, and tomato skin. Early studies suggest that it might be able to help reduce inflammation in skin and neutralize free radicalsMedium~1.1–1.7%est.
Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.9–1.35%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.15–0.65%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~3.6–5.4%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Dimethicone~22–33%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Polysilicone-11~5–7.5%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Pentaerythrityl tetraisostearate~3.2–4.9%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency

More about Pentaerythrityl tetraisostearate
Glycine soja oil~3.6–5.4%
Key activeComedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Panthenyl triacetate~2.6–3.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A stable oil-soluble derivative of vitamin B5. It can help support skin barrier and reduce inflammation in skin

More about Panthenyl triacetate
Octapeptide-45
Not recognized
Palmitoyl hexapeptide-12~1.8–2.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Palmitoyl tripeptide-1~1.6–2.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Naringenin~1.1–1.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-oxidationMoisturizing

A flavanoid that can be found in high concentrations in grapefruits, oranges, other citrus fruits, and tomato skin. Early studies suggest that it might be able to help reduce inflammation in skin and neutralize free radicals

More about Naringenin
Olea europaea leaf extract~0.9–1.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract
Arnica montana flower extract~0.55–1.25%
Irritant · high
Irritation risk
High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract
Phospholipids~0.45–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Dunaliella salina extract~0.35–0.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin

More about Dunaliella salina extract
Tocopherol~0.15–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Squalane~0.3–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Caprylic/capric triglyceride~0.15–0.65%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Propylene carbonate~0.1–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

Is used to dissolve other ingredients and create nice product texture

More about Propylene carbonate
Stearalkonium hectorite~0.05–0.25%
Formula
Irritation risk
Low

Used to create an even product consistency

More about Stearalkonium hectorite
Ingredient list view

Dimethicone, Polysilicone-11, Pentaerythrityl tetraisostearate, Glycine soja oil, Panthenyl triacetate, Unknown, Palmitoyl hexapeptide-12, Palmitoyl tripeptide-1, Naringenin, Olea europaea leaf extract, Arnica montana flower extract, Phospholipids, Dunaliella salina extract, Tocopherol, Squalane, Caprylic/capric triglyceride, Propylene carbonate, Stearalkonium hectorite

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Alastin
$265.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ALASTIN SkincareRegenerating Skin Nectar with TriHex+YOUR PRODUCTLab Series Skincare for MenMax LS Power V Lifting SerumCliniqueFresh Pressed Daily Booster with Pure Vitamin C 10%Dr. DeneseHemp Super Serum
Match—47%47%46%
Price$265.00—$44.00−$221.00—
Shared key ingredients—4 of 94 of 95 of 9
Key difference—NiacinamideSalicylic AcidHydroxypinacolone Retinoate
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

  1. 1
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  2. 2
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  3. 3
    Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmeticsncbi.nlm.nih.gov
  4. 4
    Panthenyl Triacetate Transformation, Stimulation of Metabolic Pathways, and Wound-Healing Properties in the Human Skinpubmed.ncbi.nlm.nih.gov
  5. 5
    The Therapeutic Potential of Naringenin: A Review of Clinical Trialsncbi.nlm.nih.gov
  6. 6
    Naringenin - Commentarymdedge.com
ALASTIN Skincare Regenerating Skin Nectar with TriHex+
ALASTIN SkincareRegenerating Skin Nectar with TriHex+
Buy at Alastin$265.00Amazon

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Buy at Alastin$265.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.