ADVANCED CLINICALS Hyaluronic Gel Face Cream

ADVANCED CLINICALS Hyaluronic Gel Face Cream

Efficacy37/100IrritancyHigh
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Works for

1 of 2 advertised claims delivered

Moisturizing
11 ingredients credited for this claim
Good evidence
What the product description says
“Hyaluronic Gel Face Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dipotassium glycyrrhizate, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus extract.

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~1.4–2.2%
Dipotassium glycyrrhizateKey active· HumectantEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~1–1.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.6–4%
Helianthus annuus extractKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.4–0.95%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.35–0.8%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.7–5.5%
Pyrus malus fruit extractKey activeEffect: MediumCan have some moisturizing properties due to its sugar content~2–3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.85–1.25%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.35%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.5%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.3–1.9%
Anti-aging
3 ingredients credited for this claim
Weak evidence
What the product description says
“Formulated with Vitamins B12, C, and E to promote youthful radiance.”
Source: Advanced Clinicals

Effective ingredients missing or their concentration is too low.

Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.15–0.65%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.5%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.3–1.9%

Can it cause trouble?

Irritancy
3 strong irritants: Rosmarinus officinalis leaf extract, Cymbopogon martini oil + 1 more — patch-test recommended
High risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.4–0.9%est.
Cymbopogon martini oilAromatic plant oil used in cosmetics as a fragrance. A likely irritantHigh~0.35–0.8%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.15–0.65%est.
Rosa centifolia flower extractContains essential oil. Can be irritatingHigh~0.15–0.55%est.
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~2–3%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~1.3–1.9%est.
Sea saltUsed to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentrationMedium~0.3–0.7%est.
CarrageenanHelps thicken the product formula and create a nice product formulationMedium~0.3–0.7%est.
Vaccinium angustifolium fruit extractA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lackingMedium~0.15–0.65%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.35%est.
EthylhexylglycerinA preservativeMedium~0.05–0.25%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.05–0.15%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
CarrageenanHelps thicken the product formula and create a nice product formulation3/5~0.3–0.7%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~4.3–6.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Dimethicone~3.7–5.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glycerin~2.6–4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Pyrus malus fruit extract~2–3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Ammonium acryloyldimethyltaurate/vp copolymer~1.7–2.5%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Sodium hyaluronate~1.4–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Aloe barbadensis leaf juice~1.3–1.9%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialAnti-inflammatoryReduces rednessReduces irritationAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Dipotassium glycyrrhizate~1–1.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Butylene glycol~0.85–1.25%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Caulerpa lentillifera extract~0.55–1.3%
Formula
Oryza sativa bran extract~0.45–1%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Rosmarinus officinalis leaf extract~0.4–0.9%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Helianthus annuus extract~0.4–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus extract
Cymbopogon martini oil~0.35–0.8%
Irritant · high
Irritation risk
High

Aromatic plant oil used in cosmetics as a fragrance. A likely irritant

More about Cymbopogon martini oil
Cyanocobalamin~0.35–0.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Hydroxyethylcellulose~0.35–0.8%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Sea salt~0.3–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Exfoliation

Used to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentration

More about Sea salt
Carrageenan~0.3–0.7%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5

Helps thicken the product formula and create a nice product formulation

More about Carrageenan
Vaccinium angustifolium fruit extract~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking

More about Vaccinium angustifolium fruit extract
Ascorbic acid~0.15–0.65%
Under-dosedIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-oxidationAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Polysorbate 20~0.15–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Rosa centifolia flower extract~0.15–0.55%
Irritant · high
Irritation risk
High

Contains essential oil. Can be irritating

More about Rosa centifolia flower extract
Phenoxyethanol~0.15–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Tocopherol~0.1–0.5%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Maltodextrin~0.1–0.4%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Tetrasodium glutamate diacetate~0.1–0.3%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Caprylyl glycol~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.05–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium hydroxide~0.05–0.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Hexylene glycol~0.05–0.15%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Citric acid~0.01–0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Propanediol, Dimethicone, Glycerin, Pyrus malus fruit extract, Ammonium acryloyldimethyltaurate/vp copolymer, Sodium hyaluronate, Aloe barbadensis leaf juice, Dipotassium glycyrrhizate, Butylene glycol, Caulerpa lentillifera extract, Oryza sativa bran extract, Rosmarinus officinalis leaf extract, Helianthus annuus extract, Cymbopogon martini oil, Cyanocobalamin, Hydroxyethylcellulose, Sea salt, Carrageenan, Vaccinium angustifolium fruit extract, Ascorbic acid, Polysorbate 20, Rosa centifolia flower extract, Phenoxyethanol, Tocopherol, Maltodextrin, Tetrasodium glutamate diacetate, Caprylyl glycol, Ethylhexylglycerin, Sodium hydroxide, Hexylene glycol, Citric acid

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

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ADVANCED CLINICALS Hyaluronic Gel Face Cream
ADVANCED CLINICALSHyaluronic Gel Face Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.