Wellderma G Plus Silver Peptide Ampoule

Wellderma G Plus Silver Peptide Ampoule

Efficacy100/100IrritancyMedium

Works for

Anti-aging
Niacinamide, Copper tripeptide-1 + 9 more
Works well
What the product description says
“It strengthens the skin barrier and evens out skin tone, while stimulating collagen growth with niacinamide and adenosine.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aspartic acid, copper tripeptide-1, lysine, nicotinoyl tripeptide-1, serine, sh-decapeptide-7, sh-octapeptide-4, sh-oligopeptide-9, threonine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–4.7%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.1–0.3%
LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.05–0.25%
Nicotinoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Sh-decapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Sh-octapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Sh-oligopeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.05–0.15%
Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.05–0.15%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.01–0.1%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.01–0.05%
Anti-blemish
Niacinamide, Melia azadirachta leaf extract
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–4.7%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.05–0.2%

Can it cause trouble?

Irritancy
2 strong irritants: Ocimum sanctum leaf extract, Parfum
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Punica granatum fruit extractA fruit extract that is used to add a fragrance to the product. It might have some antioxidant propertiesHigh~0.01–0.05%est.
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.05–0.2%est.
Eclipta prostrata extractA plant extract that might help neutralize free radicals in skin. It can be irritatingHigh~0.05–0.15%est.
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.05–0.15%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.01–0.05%est.
1,2-hexanediolA preservativeMedium~0.9–1.35%est.
Calcium alginateHelps to improve the product textureMedium~0.85–1.25%est.
AgarPolysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skinMedium~0.3–0.75%est.
Ficus carica fruit extractA plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effectMedium~0.01–0.1%est.
Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~0.05–0.1%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.05–0.2%est.
Disodium edtaStabilizes the product formulationMedium~0.01–0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.05–0.15%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Butylene glycol~4.4–6.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Niacinamide~3.1–4.7%
Hero · Anti-blemish
Irritation risk
Low
Works for
Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Propanediol~2.2–3.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
1,2-hexanediol~0.9–1.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Polyglycerin-3~1.3–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3
Mica~1–1.6%
Formula
Irritation risk
Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica
Titanium dioxide~1.5–2.2%
Formula
Irritation risk
Low
Works for
Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide
Calcium alginate~0.85–1.25%
Irritant · medium
Irritation risk
Medium

Helps to improve the product texture

More about Calcium alginate
Gellan gum~0.5–1.15%
Formula
Irritation risk
Low

Used to improve the product texture

More about Gellan gum
Agar~0.3–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Polysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skin

More about Agar
Iron oxides~0.15–0.7%
Formula
Irritation risk
Low
Works for
Sun protection

An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear

More about Iron oxides
Copper tripeptide-1~0.1–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Sh-decapeptide-7~0.05–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-decapeptide-7
Sh-octapeptide-4~0.05–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-octapeptide-4
Sh-oligopeptide-9~0.05–0.2%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-9
Nicotinoyl tripeptide-1~0.05–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nicotinoyl tripeptide-1
Lysine~0.05–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine
Histidine~0.05–0.25%
Formula
Irritation risk
Low
Works for
Moisturizing
More about Histidine
Arginine~0.05–0.15%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Aspartic acid~0.05–0.15%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid
Threonine~0.05–0.15%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine
Serine~0.01–0.05%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Glutamic acid~0.01–0.1%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Proline~0.05–0.1%
Formula
Irritation risk
Low
Works for
Moisturizing
More about Proline
Glycine~0.01–0.05%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Alanine~0.01–0.05%
Formula
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Valine~0.01–0.05%
Formula
Irritation risk
Low
More about Valine
Methionine~0.01–0.05%
Formula
Irritation risk
Low
More about Methionine
Isoleucine~0.01–0.05%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine
Leucine~0.01–0.05%
Formula
Irritation risk
Low
More about Leucine
Tyrosine~0.01–0.05%
Formula
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Phenylalanine~0.01–0.1%
Formula
Irritation risk
Low
More about Phenylalanine
Cysteine~0.01–0.1%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-oxidationEvens skin tone

Might help neutralize free radicals in skin and might be helpful against hyperpigmentation

More about Cysteine
Punica granatum fruit extract~0.01–0.05%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties

More about Punica granatum fruit extract
Ficus carica fruit extract~0.01–0.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect

More about Ficus carica fruit extract
Morus alba fruit extract~0.01–0.1%
Formula
Ginkgo biloba nut extract~0.01–0.05%
Formula
Sodium hyaluronate~0.05–0.15%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Peg-60 hydrogenated castor oil~0.05–0.1%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil
Adenosine~0.01–0.1%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Carbomer~0.05–0.1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Hydroxyethylcellulose~0.05–0.15%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Arginine~0.05–0.1%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Silver sulfate~0.05–0.2%
Formula
Irritation risk
Low
More about Silver sulfate
Melia azadirachta leaf extract~0.05–0.2%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Eclipta prostrata extract~0.05–0.15%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-inflammatory

A plant extract that might help neutralize free radicals in skin. It can be irritating

More about Eclipta prostrata extract
Ocimum sanctum leaf extract~0.05–0.15%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Corallina officinalis extract~0.05–0.15%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Moringa oleifera seed oil~0.05–0.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Disodium edta~0.01–0.05%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Parfum~0.01–0.05%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Butylene glycol, Niacinamide, Propanediol, 1,2-hexanediol, Polyglycerin-3, Mica, Titanium dioxide, Calcium alginate, Gellan gum, Agar, Iron oxides, Copper tripeptide-1, Sh-decapeptide-7, Sh-octapeptide-4, Sh-oligopeptide-9, Nicotinoyl tripeptide-1, Lysine, Histidine, Arginine, Aspartic acid, Threonine, Serine, Glutamic acid, Proline, Glycine, Alanine, Valine, Methionine, Isoleucine, Leucine, Tyrosine, Phenylalanine, Cysteine, Punica granatum fruit extract, Ficus carica fruit extract, Morus alba fruit extract, Ginkgo biloba nut extract, Sodium hyaluronate, Peg-60 hydrogenated castor oil, Adenosine, Carbomer, Hydroxyethylcellulose, Arginine, Silver sulfate, Melia azadirachta leaf extract, Eclipta prostrata extract, Ocimum sanctum leaf extract, Corallina officinalis extract, Moringa oleifera seed oil, Disodium edta, Parfum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
WelldermaG Plus Silver Peptide AmpouleYOUR PRODUCTArenciaDeep Water Surge Serum 30SUNGBOON EDITORSilk Peptide EGF Intensive AmpouleMEDI-PEELLuminous Silk Oil Serum
Match—82%81%80%
Price—$16.03$23.02$30.20
Shared key ingredients—16 of 247 of 2417 of 24
Key difference—Oligopeptide-1Sh-Polypeptide-9Acetyl Octapeptide-3
Irritancy Medium Medium Medium Medium
Drying alcohol————
View product Shop Shop Shop

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Product summary

"Wellderma - G Plus Silver Peptide Ampoule" is effective for: Anti-aging and Anti-blemish

Ingredient callouts

  • A good concentration of Niacinamide (3.10% - 4.70%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
  • Peptides (sh-octapeptide-4 0.05% - 0.25%, sh-decapeptide-7 0.05% - 0.25% and copper tripeptide-1 0.10% - 0.30%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Adenosine 0.01% - 0.05%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).

Price

The product retails from 12.70$ up to 29.90$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 25 studies and safety reviews.

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Wellderma G Plus Silver Peptide Ampoule
WelldermaG Plus Silver Peptide Ampoule

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