Vichy LiftActiv H.A. Epidermic Filler

Vichy LiftActiv H.A. Epidermic Filler

Efficacy87/100IrritancyLow
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Works for

2 of 2 advertised claims delivered

Moisturizing
Dipeptide diaminobutyroyl benzylamide diacetate, Calcium pantothenate + 4 more
Strong evidence
What the product description says
“Epidermic Filler, an anti-ageing hypoallergenic serum fueled by the skin-plumping and hydrating powers of hyaluronic acid.’’ , Kate, Escentual Beauty Team.”
Source: Escentual

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, sodium hyaluronate.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: dipeptide diaminobutyroyl benzylamide diacetate

Calcium pantothenateKey activeEffect: HighHelps support skin barrier function improving skin hydration and reducing sensitivity~1–1.5%
Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–1.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–5.9%
Secale cereale seed extractKey activeEffect: HighRye seed extract. Helps soften the upper layer of the skin~1.5–2.3%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~2.6–3.9%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.1–0.3%
Anti-aging
Dipeptide diaminobutyroyl benzylamide diacetate, Ascorbyl glucoside
Moderate evidence
What the product description says
“‘’Deeply quench your complexion while reducing the appearance of fine lines and wrinkles with the Vichy Lift Activ Supreme H.A.”
Source: Escentual

This product contains dipeptide diaminobutyroyl benzylamide diacetate. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–1.4%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.1–0.45%

Can it cause trouble?

Irritancy
7 flagged ingredients
Low risk
We flag 7 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Hydroxyethylpiperazine ethane sulfonic acidUsed to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical productsMedium~3.6–5.4%est.
Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~1.9–2.9%est.
Secale cereale seed extractRye seed extract. Helps soften the upper layer of the skinMedium~1.5–2.3%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Ascorbyl glucosideA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsMedium~0.1–0.45%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.25%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.1–0.3%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.9–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydroxyethylpiperazine ethane sulfonic acid~3.6–5.4%
Irritant · medium
Irritation risk
Medium
Works for
Exfoliation

Used to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical products

More about Hydroxyethylpiperazine ethane sulfonic acid
Sodium hyaluronate~2.6–3.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Peg-60 hydrogenated castor oil~1.9–2.9%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil
Secale cereale seed extract~1.5–2.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Rye seed extract. Helps soften the upper layer of the skin

More about Secale cereale seed extract
Rye seed extract
Not recognized
Calcium pantothenate~1–1.5%
Key active
Irritation risk
Low
Works for
Reduces irritationMoisturizing

Helps support skin barrier function improving skin hydration and reducing sensitivity

More about Calcium pantothenate
Dipeptide diaminobutyroyl benzylamide diacetate~0.6–1.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate
Phenoxyethanol~0.35–0.8%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Ascorbyl glucoside~0.1–0.45%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidationEvens skin tone

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about Ascorbyl glucoside
Disodium edta~0.05–0.25%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Pentylene glycol~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Code f.i.l b255659/1
Not recognized
Ingredient list view

Water, Glycerin, Hydroxyethylpiperazine ethane sulfonic acid, Sodium hyaluronate, Peg-60 hydrogenated castor oil, Secale cereale seed extract, Unknown, Calcium pantothenate, Dipeptide diaminobutyroyl benzylamide diacetate, Phenoxyethanol, Chlorphenesin, Ascorbyl glucoside, Disodium edta, Pentylene glycol, Unknown

Compare prices

Retailers ranked by price — lowest first.

Amazon UKPrice as of 11/1/2026 03:13 GMT
≈ $43.20
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Boots
≈ $52.26
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Amazon AustraliaPrice as of 10/28/2026 18:01 GMT
≈ $76.48
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Escentual
≈ $77.71
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Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
VichyLiftActiv H.A. Epidermic FillerYOUR PRODUCTAPOTCAREOPTIEYE – Wrinkle Correction
Match—52%
Price$43.20$41.51−$1.69
Shared key ingredients—3 of 6
Key difference—Niacinamide
Irritancy Low Low
Drying alcohol——
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Product summary

"Vichy - LiftActiv H. A. Epidermic Filler" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Vichy - LiftActiv H. A. Epidermic Filler ticks this box. Humectants in this product (glycerin and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moisturizer also contains Peptides (dipeptide diaminobutyroyl benzylamide diacetate 0.60% - 1.40%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 39.00£ up to 58.00£ in the United Kingdom.

For a detailed price comparison: click here.

Vichy LiftActiv H.A. Epidermic Filler
VichyLiftActiv H.A. Epidermic Filler

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As an Amazon Associate, WIMJ earns from qualifying purchases.