Codexial Enotime Global Complex Cream
Works for
2 of 2 advertised claims delivered
Anti-aging2 ingredients credited for this claimStrong support
“Its active complex acts on deep wrinkles, expression and dehydration Tensor tri-peptide features are relaxed, contraction wrinkles are reduced.Copper complex acts on the firmness and tone of the skin.High and Low Molecular Weight Hyaluronic Acids Long-lasting moisturizer and fill skin furrows for a plumping effect.The skin is intensely nourished, toned and soothed.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: dipeptide diaminobutyroyl benzylamide diacetate.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Moisturizing18 ingredients credited for this claimStrong support
“Enotime Global Complex Cream”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, cholesterol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ap, ceramide eop, ceramide np, dipeptide diaminobutyroyl benzylamide diacetate, phytosphingosine
Can it cause trouble?
Irritancy1 strong irritant: ParfumMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
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Water~45–55%
Diisopropyl sebacate~6.7–8.2%
- Irritation risk
- Low
Helps soften the upper layer of the skin without creatng a greasy finish
More about Diisopropyl sebacateDipentaerythrityl hexacaprylate/hexacaprate~3.9–4.7%
- Irritation risk
- Low
Polyglyceryl-3 methylglucose distearate~2.9–3.5%
- Irritation risk
- Medium
Helps water and oil mix together
More about Polyglyceryl-3 methylglucose distearateGlycerin~2.5–3%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinCaprylic/capric triglyceride~2.1–2.6%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideCoco-caprylate/caprate~1.7–2.1%
- Irritation risk
- Low
Helps to soften the upper layer of the skin without creating a greasy texture
More about Coco-caprylate/capratePentaerythrityl distearate~1.4–1.8%
Cetearyl alcohol~1.3–1.5%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholGlyceryl stearate~1–1.2%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearatePersea gratissima oil~0.75–1.1%
- Irritation risk
- Medium
An emollient that helps soften the skin and could be helpful in repairing its barrier function
More about Persea gratissima oilTocopheryl acetate~0.6–0.85%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateDipeptide diaminobutyroyl benzylamide diacetate~0.5–0.75%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Dipeptide diaminobutyroyl benzylamide diacetateCopper lysinate/prolinate~0.45–0.7%
- Irritation risk
- Low
Sodium hyaluronate~0.45–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateHydrolyzed hyaluronic acid~0.4–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
More about Hydrolyzed hyaluronic acidCeramide np~0.45–0.7%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npCeramide ap~0.35–0.6%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide apPhytosphingosine~0.4–0.6%
- Irritation risk
- Low
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
More about PhytosphingosineCholesterol~0.35–0.65%
- Irritation risk
- Low
An emollient that is naturally found in skin
More about CholesterolCeramide eop~0.3–0.55%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide eopCaesalpinia spinosa fruit extract~0.25–0.5%
- Irritation risk
- Low
Adenosine~0.25–0.45%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineKappaphycus alvarezii extract~0.25–0.45%
- Irritation risk
- Low
A red algae extract that can help attract water to the upper layer of the skin and might have some antioxidant properties
More about Kappaphycus alvarezii extractPhenoxyethanol~0.25–0.45%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolAmmonium acryloyldimethyltaurate/vp copolymer~0.25–0.45%
- Irritation risk
- Low
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
More about Ammonium acryloyldimethyltaurate/vp copolymerPotassium cetyl phosphate~0.25–0.5%
- Irritation risk
- Medium
Helps oil and water mix together
More about Potassium cetyl phosphateHydroxypropyl starch phosphate~0.25–0.5%
- Irritation risk
- Medium
Helps oil and water mix together and used to stabilize product formulations
More about Hydroxypropyl starch phosphateStearyl alcohol~0.3–0.5%
- Irritation risk
- Low
An emollient that helps soften the skin
More about Stearyl alcoholChlorphenesin~0.16–0.32%
Sodium lauroyl lactylate~0.2–0.4%
- Irritation risk
- Medium
Helps water and oil mix together
More about Sodium lauroyl lactylateDisodium edta~0.15–0.3%
Methylglucoside phosphate~0.15–0.3%
- Irritation risk
- Low
Xanthan gum~0.15–0.25%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumCarbomer~0.1–0.2%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerEthylhexylglycerin~0.1–0.15%
Parfum~0.05–0.1%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumIngredient list view
Water, Diisopropyl sebacate, Dipentaerythrityl hexacaprylate/hexacaprate, Polyglyceryl-3 methylglucose distearate, Glycerin, Caprylic/capric triglyceride, Coco-caprylate/caprate, Pentaerythrityl distearate, Cetearyl alcohol, Glyceryl stearate, Persea gratissima oil, Tocopheryl acetate, Dipeptide diaminobutyroyl benzylamide diacetate, Copper lysinate/prolinate, Sodium hyaluronate, Hydrolyzed hyaluronic acid, Ceramide np, Ceramide ap, Phytosphingosine, Cholesterol, Ceramide eop, Caesalpinia spinosa fruit extract, Adenosine, Kappaphycus alvarezii extract, Phenoxyethanol, Ammonium acryloyldimethyltaurate/vp copolymer, Potassium cetyl phosphate, Hydroxypropyl starch phosphate, Stearyl alcohol, Chlorphenesin, Sodium lauroyl lactylate, Disodium edta, Methylglucoside phosphate, Xanthan gum, Carbomer, Ethylhexylglycerin, Parfum
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| CodexialEnotime Global Complex CreamYOUR PRODUCT | Rephrintense hydration cream 1.0 | NERISHSoy Ceramide Barrier Cream | NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream | |
|---|---|---|---|---|
| Match | — | 57% | 56% | 56% |
| Price | $51.51 | — | $16.11−$35.40 | $39.59−$11.92 |
| Shared key ingredients | — | 10 of 13 | 10 of 13 | 9 of 13 |
| Key difference | — | Niacinamide | Niacinamide | Copper Tripeptide-1 |
| Irritancy | Medium | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
"Codexial - Enotime Global Complex Cream" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Glycerin, hydrolyzed hyaluronic acid and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide eop, ceramide np, phytosphingosine, cholesterol and persea gratissima oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- As a plus, this moisturizer also contains Ceramides (ceramide eop 0.30% - 0.55%, phytosphingosine 0.40% - 0.60%, ceramide ap 0.35% - 0.60% and ceramide np 0.45% - 0.70%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- This moisturizer also contains Peptides (dipeptide diaminobutyroyl benzylamide diacetate 0.50% - 0.75%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Adenosine 0.25% - 0.45%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Irritation risk
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 127.89$ in the United States and from 38.96£ up to 45.60£ in the United Kingdom.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 10 studies and safety reviews.
- 1
- 2Safety Assessment of Alkyl Esters as Used in Cosmeticscir-safety.org
- 3Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 4
- 5Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
- 6Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
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