Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Anti-blemish
- Evens skin tone
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 4
Key actives
Product Summary
Judging from the ingredient list, "VARI: HOPE - Biotics Signature Cream" works well for improving skin hydration As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (glycerin, hydrolyzed collagen, butylene glycol and propylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, hydrolyzed collagen, cetearyl alcohol, cyclopentasiloxane and ethylhexyl palmitate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- As a plus, this moisturizer also contains Ceramides (ceramide np 0.15% - 0.25%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 35.00$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Smoothens wrinkles and refines rough skin texture for smooth, firm-looking skin. Skin irritation test completed.
Source: Yesstyle
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An enzyme-based exfoliant
Moisturizing
What does the product description say?
Biotics Signature Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed collagen.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: hydrolyzed collagen, cetearyl alcohol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A fermented sweet black tea. There is no studies on particular benefits of this ingredient in skin. It can help attract water to the upper layer of the skin, and might have some anti-oxidant effect. It is used in skincare for mostly marketing purposes because of the popularity of kombucha drinks
A product of bacterial fermentation. Can help attract water to the upper layer of the skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking
An emollient that helps soften the skin and create a nice product texture
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Used to preserve products, dissolve other ingredients and create a nice product texture
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
A silicone that serves as an emollient. Helps create a nice non-greasy feels
Helps products spread more easily and works as an emollient to soften skin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 VARI:HOPE Biotics Signature Cream | Current | $35.00 | |
I'm from Mushroom Collagen Cream | 86% | $30.26 | |
COSNORI Panthenol Barrier Cream | 86% | $16.74 | |
 NEOGEN X SUR.MEDIC Surmedic 24K Gold Caviar Repair Vital Cream | 85% | $39.59 | |
 23 years old Bakuchiol A Cream | 85% | $24.71 | |
 Evercell Radiance Lifting Cream | 84% | $12.35 |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties
A product of bacterial fermentation. Can help attract water to the upper layer of the skin
Anti-bacterial compound that works as a preservative
A fermented sweet black tea. There is no studies on particular benefits of this ingredient in skin. It can help attract water to the upper layer of the skin, and might have some anti-oxidant effect. It is used in skincare for mostly marketing purposes because of the popularity of kombucha drinks
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
An enzyme-based exfoliant
Anti-bacterial compound that works as a preservative
A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating
Used to preserve products, dissolve other ingredients and create a nice product texture
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Used to improve product texture and help oil and water mix together
Comedogenic ingredients
An emollient that helps soften the skin and create a nice product texture
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
All ingredients
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
An emollient that helps soften the skin and create a nice product texture
Used to stabilize product formulations and create a nice product texture
Helps products spread more easily and works as an emollient to soften skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Used to preserve products, dissolve other ingredients and create a nice product texture
A silicone that serves as an emollient. Helps create a nice non-greasy feels
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Used to improve product texture and help oil and water mix together
An aromatic blend of unspecified and possibly irritating ingredients
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A product of bacterial fermentation. Can help attract water to the upper layer of the skin
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking
An enzyme-based exfoliant
Anti-bacterial compound that works as a preservative
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A fermented sweet black tea. There is no studies on particular benefits of this ingredient in skin. It can help attract water to the upper layer of the skin, and might have some anti-oxidant effect. It is used in skincare for mostly marketing purposes because of the popularity of kombucha drinks
A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Ingredient list view
Water, Cyclopentasiloxane, Ethylhexyl palmitate, Dimethicone/vinyl dimethicone crosspolymer, Dicaprylyl carbonate, Glycerin, Butylene glycol, Niacinamide, Pentylene glycol, Cyclohexasiloxane, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, 1,2-hexanediol, Steareth-2, Simmondsia chinensis seed oil, Polyacrylamide, Parfum, C13-14 isoparaffin, Xanthan gum, Avena sativa kernel oil, Fructan, Disodium edta, Laureth-7, Adenosine, Bacillus ferment, Ethylhexylglycerin, Propylene glycol, Prunella vulgaris extract, Fucus vesiculosus extract, Lactobacillus/soybean ferment extract, Lactobacillus/acerola cherry ferment, Lactobacillus/punica granatum fruit ferment extract, Lactobacillus/wasabia japonica root ferment extract, Lactobacillus/hibiscus sabdariffa flower ferment filtrate, Butyrospermum parkii butter, Saccharomyces/xylinum/black tea ferment, Panax ginseng root extract, Ceramide np, Hydrolyzed collagen
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- 5: Final Report on the Safety Assessment of Steareth-2,-4,-6,-7,-10,-11,-13,-15, and-20
- Safety Assessment of Isoparaffins as Used in Cosmetics
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Ginseng in Dermatology: A Review
- Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin