The Saem

The Saem Snail Essential EX Wrinkle Solution Multi Cream

Name: The Saem - Snail Essential EX Wrinkle Solution Multi Cream
Brand: The Saem

Efficacy100/100IrritancyMedium

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Works for

2 of 2 advertised claims delivered

Anti-aging

11 ingredients credited for this claim

Strong support

What the product description says

“Offers brightening and wrinkle improvement effect to create smooth and glowy skin.”

Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide, palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-8, copper tripeptide-1, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.3%

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Camellia sinensis seed oilEffect: Low, below effective doseA plant oil that helps to soften the upper layer of the skin and can help restore the skin barrier. Might have some anti-oxidant effect~0.25–0.45%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.7–1.05%

Moisturizing

53 ingredients credited for this claim

Strong support

What the product description says

“Snail Essential EX Wrinkle Solution Multi Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: fructooligosaccharides, fructose.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, copernicia cerifera wax.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-8, ceramide np, copper tripeptide-1, niacinamide, palmitoyl hexapeptide-12, palmitoyl tripeptide-5

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.2–0.4%

Synthetic beeswaxKey activeEffect: HighHelps soften the upper layer of the skin~0.25–0.45%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.5%

Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.45–0.65%

Echium plantagineum seed oilKey activeEffect: HighA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin~0.25–0.45%

FructooligosaccharidesKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.25–0.45%

FructoseKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.25–0.45%

Copernicia cerifera waxKey active· Emollient, OcclusiveEffect: HighHelps to soften the upper layer of the skin and create a nice product consistency~0.5–0.8%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5.1–6.2%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.15–0.25%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.25–0.45%

Helianthus annuus seed oil unsaponifiablesKey active· EmollientEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.3%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Hydrolyzed glycosaminoglycansKey active· HumectantEffect: HighLong sugars that help attract water to the upper layer of the skin~0.25–0.4%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%

Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~0.3–0.55%

Snail secretion filtrateKey active· HumectantEffect: HighTypically contains hyaluronic acid that helps attract water to the upper layer of the skin. Might contain allantoin that is helpful in calming down inflammation. There is no evidence that it can have any further benefits for the skin, especially when used in skincare products~0.25–0.45%

Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.2–0.4%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%

Saccharum officinarum extractKey activeEffect: HighSugar extract that helps attract water to the upper layer of the skin~0.3–0.6%

Plukenetia volubilis seed oilKey active· Emollient, OcclusiveEffect: HighA plant oil that works as a good moisturizer by softening the upper layer of the skin. Might be helpful in reducing inflammation in skin and reducing blemishes due to the large content of linoleic acid~0.25–0.5%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~4.1–5%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.35–0.65%

Diisostearyl malateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin~0.3–0.5%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.25–0.45%

Honey extractKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin~0.25–0.45%

Macadamia integrifolia seed oilKey active· EmollientEffect: MediumA plant oil that helps soften the upper layer of the skin~1.9–2.3%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.65–0.95%

Propolis extractKey activeEffect: MediumA complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritating~0.25–0.5%

Royal jelly extractKey active· HumectantEffect: MediumA compound secreted by bees. Might be able to attract water to the top layer of the skin. Avoid if sensitive to honey and bee products~0.25–0.45%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3–3.6%

Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.3–0.55%

Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.3–0.55%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.2–1.5%

Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~1.6–2%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.55%

Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~2.3–2.9%

Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.25–0.5%

Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.25–0.5%

Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.7–1.05%

Argania spinosa kernel oilUnder-dosedEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.25–0.45%

Simmondsia chinensis seed oilUnder-dosedEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.25–0.5%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.6%

Camellia sinensis seed oilUnder-dosedEffect: HighA plant oil that helps to soften the upper layer of the skin and can help restore the skin barrier. Might have some anti-oxidant effect~0.25–0.45%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.4–0.6%

Evens skin tone

Not advertised by the brand · 1 ingredient credited for this claim

Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Anti-blemish

Not advertised by the brand · 2 ingredients credited for this claim

Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.25–0.45%

Can it cause trouble?

Irritancy

2 strong irritants: Ocimum sanctum leaf extract, Parfum

Medium risk

We flagged 27 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.25–0.5%est.

Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.25–0.45%est.

Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.2–0.4%est.

Cardiospermum halicacabum flower/leaf/vine extractA plant extract that might have some anti-inflammatory and anti-oxidant properties but evidence is missingHigh~0.25–0.45%est.

Propolis extractA complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritatingHigh~0.25–0.5%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.15%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~4.1–5%est.

Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~1.6–2%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.2–1.5%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.35–0.65%est.

Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.3–0.55%est.

Snail secretion filtrateTypically contains hyaluronic acid that helps attract water to the upper layer of the skin. Might contain allantoin that is helpful in calming down inflammation. There is no evidence that it can have any further benefits for the skin, especially when used in skincare productsMedium~0.25–0.45%est.

Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.25–0.5%est.

Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.25–0.45%est.

Echium plantagineum seed oilA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skinMedium~0.25–0.45%est.

Honey extractHelps attract water to the upper layer of the skinMedium~0.25–0.45%est.

Royal jelly extractA compound secreted by bees. Might be able to attract water to the top layer of the skin. Avoid if sensitive to honey and bee productsMedium~0.25–0.45%est.

Diisostearyl malateHelps to soften the upper layer of the skinMedium~0.3–0.5%est.

Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~0.3–0.5%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.5%est.

Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.25–0.5%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.6%est.

Sorbitan laurateHelps water and oil mix togetherMedium~0.25–0.5%est.

Benzyl glycolHelps dissolve other ingredients and preserve productsMedium~0.25–0.45%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.2–0.4%est.

Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.25–0.45%est.

Comedogenic

7 ingredients rated 2 or more on the 0–5 pore-clogging scale

7 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.7–1.05%est.

Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.45–0.65%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.35–0.65%est.

Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.2–0.4%est.

Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~0.3–0.55%est.

Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.25–0.5%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.65–0.95%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~5.1–6.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Olea europaea fruit oil~4.1–5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Butylene glycol~3–3.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Cyclohexasiloxane~2.3–2.9%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

Macadamia integrifolia seed oil~1.9–2.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A plant oil that helps soften the upper layer of the skin

More about Macadamia integrifolia seed oil

Cetyl ethylhexanoate~1.6–2%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate

Niacinamide~1.4–1.7%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Pentylene glycol~1.2–1.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Polyglyceryl-3 distearate~0.95–1.15%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-3 distearate

Butyrospermum parkii butter~0.7–1.05%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Cetearyl alcohol~0.65–0.95%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

2-hexanol~0.45–0.7%

Formula

Irritation risk: Low

More about 2-hexanol

Copernicia cerifera wax~0.5–0.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product consistency

More about Copernicia cerifera wax

Chondrus crispus extract~0.45–0.65%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract

Chlorella vulgaris extract~0.35–0.65%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-inflammatory

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Saccharum officinarum extract~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Sugar extract that helps attract water to the upper layer of the skin

More about Saccharum officinarum extract

Melia azadirachta flower extract~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract

Ocimum sanctum leaf extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract

Melia azadirachta leaf extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract

Snail secretion filtrate~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-inflammatory

Typically contains hyaluronic acid that helps attract water to the upper layer of the skin. Might contain allantoin that is helpful in calming down inflammation. There is no evidence that it can have any further benefits for the skin, especially when used in skincare products

More about Snail secretion filtrate

Curcuma longa root extract~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract

Corallina officinalis extract~0.2–0.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract

Vincetoxicum atratum extract~0.2–0.4%

Formula

Irritation risk: Low

More about Vincetoxicum atratum extract

Candida bombicola

Not recognized

Glucose~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Methyl rapeseedate

Not recognized

Camellia japonica seed oil~0.25–0.45%

Formula

Irritation risk: Low

A plant oil that helps to soften the upper layer of the skin and can help restore skin's barrier function. Might have an anti-oxidant effect

More about Camellia japonica seed oil

Helianthus annuus seed oil~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Plukenetia volubilis seed oil~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A plant oil that works as a good moisturizer by softening the upper layer of the skin. Might be helpful in reducing inflammation in skin and reducing blemishes due to the large content of linoleic acid

More about Plukenetia volubilis seed oil

Simmondsia chinensis seed oil~0.25–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil

Argania spinosa kernel oil~0.25–0.45%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil

Camellia sinensis seed oil~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-agingAnti-oxidation

A plant oil that helps to soften the upper layer of the skin and can help restore the skin barrier. Might have some anti-oxidant effect

More about Camellia sinensis seed oil

Althaea rosea flower extract~0.25–0.45%

Formula

Irritation risk: Low

More about Althaea rosea flower extract

Aureobasidium pullulans ferment~0.25–0.45%

Formula

Irritation risk: Low

More about Aureobasidium pullulans ferment

Tuber melanosporum extract~0.25–0.45%

Formula

Irritation risk: Low

More about Tuber melanosporum extract

Echium plantagineum seed oil~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-inflammatory

A plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin

More about Echium plantagineum seed oil

Helianthus annuus seed oil unsaponifiables~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil unsaponifiables

Hydrolyzed collagen extract~0.25–0.5%

Formula

Irritation risk: Low

More about Hydrolyzed collagen extract

Honey extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Honey extract

Royal jelly extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A compound secreted by bees. Might be able to attract water to the top layer of the skin. Avoid if sensitive to honey and bee products

More about Royal jelly extract

Cardiospermum halicacabum flower/leaf/vine extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory and anti-oxidant properties but evidence is missing

More about Cardiospermum halicacabum flower/leaf/vine extract

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Propolis extract~0.25–0.5%

Key activeIrritant · high

Irritation risk: High

Works for

MoisturizingAntibacterialAnti-oxidation

A complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritating

More about Propolis extract

Hydrolyzed hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Diisostearyl malate~0.3–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps to soften the upper layer of the skin

More about Diisostearyl malate

Isopropyl myristate~0.3–0.55%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate

Synthetic beeswax~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Synthetic beeswax

Glyceryl stearate~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Polyglyceryl-3 methylglucose distearate~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate

Sodium polyacrylate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate

Hydroxyacetophenone~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Palmitic acid~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid

Stearic acid~0.4–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Glucose~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Glyceryl stearate citrate~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate

Fructooligosaccharides~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Help attract water to the upper layer of the skin

More about Fructooligosaccharides

Fructose~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Fructose

Adenosine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Sodium phytate~0.25–0.45%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Isopropyl palmitate~0.25–0.5%

Comedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate

Tocopherol~0.25–0.5%

Formula

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Octyldodecanol~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol

Ethylhexylglycerin~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Caprylic/capric triglyceride~0.3–0.6%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Propanediol~0.25–0.5%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Hydrogenated lecithin~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Sorbitan laurate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Sorbitan laurate

Ceramide np~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Hydroxyethylcellulose~0.25–0.5%

Formula

Irritation risk: Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose

Benzyl glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients and preserve products

More about Benzyl glycol

Acetyl dipeptide-1 cetyl ester~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingReduces irritationAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester

Hydrolyzed glycosaminoglycans~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Hydrolyzed glycosaminoglycans

Palmitoyl tripeptide-5~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Sodium hyaluronate crosspolymer~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Palmitoyl hexapeptide-12~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12

Hydroxypropyltrimonium hyaluronate~0.2–0.4%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Sodium stearoyl glutamate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate

Copper tripeptide-1~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Acetyl hexapeptide-8~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Sodium acetylated hyaluronate~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Xanthan gum~0.1–0.2%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Parfum~0.1–0.15%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Ingredient list view

Water, Glycerin, Olea europaea fruit oil, Butylene glycol, Cyclohexasiloxane, Macadamia integrifolia seed oil, Cetyl ethylhexanoate, Niacinamide, Pentylene glycol, Polyglyceryl-3 distearate, Butyrospermum parkii butter, Cetearyl alcohol, 2-hexanol, Copernicia cerifera wax, Chondrus crispus extract, Chlorella vulgaris extract, Saccharum officinarum extract, Melia azadirachta flower extract, Ocimum sanctum leaf extract, Melia azadirachta leaf extract, Snail secretion filtrate, Curcuma longa root extract, Corallina officinalis extract, Vincetoxicum atratum extract, Unknown, Glucose, Unknown, Camellia japonica seed oil, Helianthus annuus seed oil, Plukenetia volubilis seed oil, Simmondsia chinensis seed oil, Argania spinosa kernel oil, Camellia sinensis seed oil, Althaea rosea flower extract, Aureobasidium pullulans ferment, Tuber melanosporum extract, Echium plantagineum seed oil, Helianthus annuus seed oil unsaponifiables, Hydrolyzed collagen extract, Honey extract, Royal jelly extract, Cardiospermum halicacabum flower/leaf/vine extract, Sodium hyaluronate, Propolis extract, Hydrolyzed hyaluronic acid, Hyaluronic acid, Diisostearyl malate, Isopropyl myristate, Synthetic beeswax, Glyceryl stearate, Polyglyceryl-3 methylglucose distearate, Sodium polyacrylate, Hydroxyacetophenone, Palmitic acid, Stearic acid, Glucose, Glyceryl stearate citrate, Fructooligosaccharides, Fructose, Adenosine, Sodium phytate, Isopropyl palmitate, Tocopherol, Octyldodecanol, Ethylhexylglycerin, Caprylic/capric triglyceride, Propanediol, Hydrogenated lecithin, Sorbitan laurate, Ceramide np, Hydroxyethylcellulose, Benzyl glycol, Acetyl dipeptide-1 cetyl ester, Hydrolyzed glycosaminoglycans, Palmitoyl tripeptide-5, Sodium hyaluronate crosspolymer, Palmitoyl hexapeptide-12, Hydroxypropyltrimonium hyaluronate, Sodium stearoyl glutamate, Copper tripeptide-1, Acetyl hexapeptide-8, Sodium acetylated hyaluronate, Xanthan gum, Parfum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	The SaemSnail Essential EX Wrinkle Solution Multi CreamYOUR PRODUCT	TOSOWOONGJeju Mayu Cream	NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream	HSGNRetinally Liposomal Retinal Cream
Match	—	78%	76%	76%
Price	$23.00	—	$60.00+$37.00	$13.20−$9.80
Shared key ingredients	—	14 of 36	15 of 36	13 of 36
Key difference	—	Oligopeptide-1	Nonapeptide-1	Hexapeptide-9
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"The Saem - Snail Essential EX Wrinkle Solution Multi Cream" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, fructooligosaccharides, fructose, glycerin and hyaluronic acid) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, helianthus annuus seed oil unsaponifiables, isopropyl myristate, chondrus crispus extract and copernicia cerifera wax in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

As a plus, this moisturizer also contains Ceramides (ceramide np 0.30% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.15% - 0.30%, copper tripeptide-1 0.15% - 0.30%, palmitoyl hexapeptide-12 0.20% - 0.40%, palmitoyl tripeptide-5 0.20% - 0.40% and acetyl dipeptide-1 cetyl ester 0.25% - 0.45%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.25% - 0.45%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: caprylic/capric triglyceride, vitamin e, stearic acid, camellia sinensis seed oil, agran oil and jojoba oil

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 23.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 36 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oilonlinelibrary.wiley.com
3
Fatty acids profile of oil from nine varieties of Macadamia nuttandfonline.com
4
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
5
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
6
Melia azedarachmdedge.com
7
Preliminary and Pharmacological Profile of Melia azedarach L.: An Overviewjapsonline.com
8
The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skinncbi.nlm.nih.gov
9
The Effects of Snail Secretion Filtrate on the damaged skin barrier's recovery of the Atopic dermatitiskoreascience.or.kr
10
Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243–1264. doi:10.1002/ptr.5640ncbi.nlm.nih.gov
11
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
12
Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
13
Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
14
Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
15
Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
16
Chemical composition of Sacha Inchi ( Plukenetia volubilis L.) seeds and characteristics of their lipid fractionresearchgate.net
17
Natural vegetable fats in the prevention of irritant contact dermatitisncbi.nlm.nih.gov
18
Characteristics of Tea Seed Oil in Comparison with Sunflower and Olive Oils and Its Effect as a Natural Antioxidantlink.springer.com
19
Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acidsncbi.nlm.nih.gov
20
Evidence for the efficacy and safety of topical herbal drugs in dermatology: Part I: Anti-inflammatory agentssciencedirect.com
21
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
22
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
23
Propolis: A Wonder Bees Product and Its Pharmacological Potentialsncbi.nlm.nih.gov
24
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
25
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
26
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
27
Final Report on the Safety Assessment of Isopropyl Isostearatejournals.sagepub.com
28
Vitamin E in dermatologyncbi.nlm.nih.gov
29
Vitamin E and Skin Healthlpi.oregonstate.edu
30
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
31
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
32
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
33
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
34
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
35
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com
36
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com

The SaemSnail Essential EX Wrinkle Solution Multi Cream

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