The Saem Cell Renew Bio Emulsion

The Saem Cell Renew Bio Emulsion

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Anti-aging
3 ingredients credited for this claim
Strong support
What the product description says
“Provides dual functional treatments with skin-whitening and anti-wrinkle effects.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: sh-oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%
Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%
Moisturizing
18 ingredients credited for this claim
Strong support
What the product description says
“A soft-textured emulsion that forms the skin's moisture barrier, refining skin complexion and restoring vitality and smooth skin.”
Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, mannitol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, persea gratissima fruit extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, sh-oligopeptide-1

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.35–0.65%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.3–0.6%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%
Persea gratissima fruit extractKey active· EmollientEffect: High~0.3–0.55%
Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.8–3.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.4–4.2%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~0.8–1.15%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.75–1.15%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.6–0.9%
Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~0.75–1.1%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.4–0.6%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.2–2.7%
Ethylhexyl stearate· EmollientEffect: LowHelps soften the upper layer of the skin~1.2–1.5%
Caprylyl methiconeEffect: LowA type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin~1.3–1.6%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.7–1%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.7–1.05%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.35–0.65%
Anemarrhena asphodeloides root extractEffect: LowA plant extract that might have some anti-oxidant properties~0.2–0.35%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%
ErgothioneineUnder-dosedEffect: HighCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.2–0.4%
Anti-blemish
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%
Evens skin tone
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.35–0.65%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.1%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.4–4.2%est.
1,2-hexanediolA preservativeMedium~0.9–1.1%est.
EthylhexylglycerinA preservativeMedium~0.55–0.8%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.35–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.15–0.25%est.
Myristic acidHelps oil and water mix together. Could be comedogenicMedium~0.2–0.35%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Myristic acidHelps oil and water mix together. Could be comedogenic3/5~0.2–0.35%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~0.8–1.15%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Neral~5.3–6.5%
Formula
Irritation risk
Low
More about Neral
Water~4.4–5.4%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~3.4–4.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~2.8–3.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~2.2–2.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Niacinamide~1.9–2.3%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
1,2-hexanediol~0.9–1.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl methicone~1.3–1.6%
Formula
Irritation risk
Low
Works for
Moisturizing

A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin

More about Caprylyl methicone
Ethylhexyl stearate~1.2–1.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl stearate
Polyglyceryl-3 distearate~1–1.2%
Formula
Irritation risk
Low
Works for
Cleansing
More about Polyglyceryl-3 distearate
Methyl gluceth-10~0.8–1.2%
Formula
Irritation risk
Low
Works for
Cleansing
More about Methyl gluceth-10
Glyceryl stearate se~0.8–1.15%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Hydrogenated polydecene~0.75–1.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene
Polyglyceryl-6 isostearate~0.75–1.1%
Formula
Irritation risk
Low
Works for
Cleansing
More about Polyglyceryl-6 isostearate
Cetyl alcohol~0.75–1.15%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Diphenyl dimethicone~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing
More about Diphenyl dimethicone
Palmitic acid~0.7–1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Stearic acid~0.7–1.05%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Glyceryl stearate citrate~0.6–0.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Carbomer~0.55–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Ethylhexylglycerin~0.55–0.8%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Tromethamine~0.5–0.75%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Eryngium maritimum callus culture filtrate~0.5–0.7%
Formula
Milk lipids~0.35–0.65%
Formula
Irritation risk
Low
More about Milk lipids
Theanine~0.4–0.65%
Formula
Irritation risk
Low
More about Theanine
Glutathione~0.35–0.65%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Hydrogenated polyisobutene~0.4–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Mannitol~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Adenosine~0.3–0.55%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Maltodextrin~0.3–0.5%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Persea gratissima fruit extract~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Persea gratissima fruit extract
Ergothioneine~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Anemarrhena asphodeloides root extract~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Anemarrhena asphodeloides root extract
Caramel~0.15–0.3%
Formula
Irritation risk
Low
More about Caramel
Disodium edta~0.15–0.25%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Myristic acid~0.2–0.35%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Cleansing

Helps oil and water mix together. Could be comedogenic

More about Myristic acid
Sh-oligopeptide-1~0.1–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1
Parfum~0.05–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Neral, Water, Caprylic/capric triglyceride, Glycerin, Butylene glycol, Niacinamide, 1,2-hexanediol, Caprylyl methicone, Ethylhexyl stearate, Polyglyceryl-3 distearate, Methyl gluceth-10, Glyceryl stearate se, Hydrogenated polydecene, Polyglyceryl-6 isostearate, Cetyl alcohol, Diphenyl dimethicone, Palmitic acid, Stearic acid, Glyceryl stearate citrate, Carbomer, Ethylhexylglycerin, Tromethamine, Eryngium maritimum callus culture filtrate, Milk lipids, Theanine, Glutathione, Hydrogenated polyisobutene, Mannitol, Adenosine, Maltodextrin, Persea gratissima fruit extract, Ergothioneine, Anemarrhena asphodeloides root extract, Caramel, Disodium edta, Myristic acid, Sh-oligopeptide-1, Parfum

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$37.90
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
The SaemCell Renew Bio EmulsionYOUR PRODUCTTOSOWOONGCica Snail CreamSaturday SkinCarrot + Niacinamide Moisturizing CreampreangeVit B5 Emulsion
Match—84%79%79%
Price$37.90$16.40−$21.50$28.56−$9.34$21.15−$16.75
Shared key ingredients—5 of 84 of 84 of 8
Key difference—Copper Tripeptide-1Sh-Polypeptide-22Panthenol
Irritancy Medium Medium Medium Low
Drying alcohol————
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Product summary

"The Saem - Cell Renew Bio Emulsion" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. The Saem - Cell Renew Bio Emulsion ticks this box. Glycerin, mannitol and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (persea gratissima fruit extract, caprylic/capric triglyceride, cetyl alcohol, ethylhexyl stearate and glyceryl stearate citrate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (1.90% - 2.30%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
  • We like that this moisturizer contains peptides (sh-oligopeptide-1 0.10% - 0.20%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.30% - 0.55%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: ergothioneine

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 37.90$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.

  1. 1
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  5. 5
  6. 6
The Saem Cell Renew Bio Emulsion
The SaemCell Renew Bio Emulsion

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