skintific PDRN Bright & Smooth Moisture Gel Cream Moisturizer

skintific PDRN Bright & Smooth Moisture Gel Cream Moisturizer

Efficacy100/100IrritancyMedium
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Works for

3 of 3 advertised claims delivered

Anti-aging
Niacinamide
Strong evidence
What the product description says
“supports anti-aging”
Source: Skintific

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–5.3%
Moisturizing
Niacinamide, Bacillus ferment + 17 more
Strong evidence
What the product description says
“moisturizer”
Source: Skintific

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, mannitol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide

Bacillus fermentKey activeEffect: HighA product of bacterial fermentation. Can help attract water to the upper layer of the skin~0.3–0.55%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.35–0.65%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–5.3%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.5–0.7%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.45–0.65%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.4–0.6%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.7–2.1%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.2–0.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2–2.4%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.3–0.5%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.2–3.9%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.5%
Olea europaea oil unsaponifiablesKey activeEffect: MediumHelp soften the upper layer of the skin~0.35–0.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.55%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~6.5–7.9%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.15–0.3%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.55%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~2.4–2.9%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.3–0.55%
Evens skin tone
Niacinamide
Strong evidence
What the product description says
“Fades blemishes and dark spots”
Source: Skintific

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–5.3%
Anti-blemish
Not advertised by the brand · Niacinamide
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–5.3%

Can it cause trouble?

Irritancy
2 strong irritants: Sclareolide, Aroma
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
SclareolideDerived from clary sage. Used as a fragrance. Can be irritatingHigh~1.1–1.3%est.
AromaAn unspecified blend of fragrant irritating ingredientsHigh~0.1–0.15%est.
Ci 16035A red dyeHigh~0.1–0.15%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2–2.4%est.
Haberlea rhodopensis leaf extractA plant extract that if used in high concentration might help to neutralize free radicals in skinMedium~0.55–0.8%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.4–0.6%est.
Sucrose polystearateHelps oil and water mix togetherMedium~0.3–0.55%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.3–0.55%est.
1,2-hexanediolA preservativeMedium~0.25–0.45%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.45%est.
Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.25–0.4%est.
Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.2–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.
EthylhexylglycerinA preservativeMedium~0.1–0.2%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ci 16035A red dye3/5~0.1–0.15%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.55%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Butylene glycol~6.5–7.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Niacinamide~4.4–5.3%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Dimethicone~3.2–3.9%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Isononyl isononanoate~2.4–2.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Caprylic/capric triglyceride~2–2.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Squalane~1.7–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Sodium dna~1.4–1.7%
Formula
Irritation risk
Low
More about Sodium dna
Sclareolide~1.1–1.3%
Irritant · high
Irritation risk
High

Derived from clary sage. Used as a fragrance. Can be irritating

More about Sclareolide
Malt extract~0.9–1.1%
Formula
Irritation risk
Low
More about Malt extract
Diglucosyl gallic acid~0.65–1%
Formula
Haberlea rhodopensis leaf extract~0.55–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that if used in high concentration might help to neutralize free radicals in skin

More about Haberlea rhodopensis leaf extract
Sodium acetylated hyaluronate~0.5–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Sodium hyaluronate~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Sodium hyaluronate crosspolymer~0.4–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Hydrolyzed sodium hyaluronate~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Olea europaea oil unsaponifiables~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Olea europaea oil unsaponifiables
Bacillus ferment~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A product of bacterial fermentation. Can help attract water to the upper layer of the skin

More about Bacillus ferment
Cyanocobalamin~0.3–0.5%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Sucrose polystearate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sucrose polystearate
Pentylene glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Cetearyl alcohol~0.3–0.55%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glycerin~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
1,2-hexanediol~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Hydroxyacetophenone~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Ammonium acryloyldimethyltaurate/vp copolymer~0.25–0.45%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Sodium polyacryloyldimethyl taurate~0.25–0.4%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.25–0.45%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Mannitol~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Sodium stearoyl lactylate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate
Citric acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Polysilicone-11~0.15–0.3%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Ethylhexylglycerin~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Aroma~0.1–0.15%
Irritant · high
Irritation risk
High

An unspecified blend of fragrant irritating ingredients

More about Aroma
Ci 16035~0.1–0.15%
Comedogenic 3/5Irritant · high
Irritation risk
High
Comedogenicity
3/5

A red dye

More about Ci 16035
Ingredient list view

Water, Butylene glycol, Niacinamide, Dimethicone, Isononyl isononanoate, Caprylic/capric triglyceride, Squalane, Sodium dna, Sclareolide, Malt extract, Diglucosyl gallic acid, Haberlea rhodopensis leaf extract, Sodium acetylated hyaluronate, Sodium hyaluronate, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Olea europaea oil unsaponifiables, Bacillus ferment, Cyanocobalamin, Sucrose polystearate, Pentylene glycol, Cetearyl alcohol, Glycerin, 1,2-hexanediol, Hydroxyacetophenone, Ammonium acryloyldimethyltaurate/vp copolymer, Glyceryl stearate, Sodium polyacryloyldimethyl taurate, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Mannitol, Sodium stearoyl lactylate, Citric acid, Polysilicone-11, Ethylhexylglycerin, Aroma, Ci 16035

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Amazon USPrice as of 10/22/2026 03:06 GMT
$17.90
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
skintificPDRN Bright & Smooth Moisture Gel Cream MoisturizerYOUR PRODUCTDr.Reju-AllAdvanced PDRN Rejuvenating Cream MaxRéViveFull-Size Hydrogel Moisturizer GiftCos De BAHAHyaluronic acid gel cream
Match—91%90%90%
Price$17.90$67.01+$49.11$195.00+$177.10$12.99−$4.91
Shared key ingredients—4 of 148 of 147 of 14
Key difference—AdenosineHexapeptide-9Adenosine
Irritancy Medium Low Medium Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 13 studies and safety reviews.

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skintific PDRN Bright & Smooth Moisture Gel Cream Moisturizer
skintificPDRN Bright & Smooth Moisture Gel Cream Moisturizer

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As an Amazon Associate, WIMJ earns from qualifying purchases.