SkinCeuticals

SkinCeuticals Hyaluronic Acid Intensifier Multi-Glycan

Name: SkinCeuticals - Hyaluronic Acid Intensifier Multi-Glycan
Brand: SkinCeuticals

Efficacy87/100IrritancyHigh

See all ingredients

Works for

Anti-aging

Adenosine, Tocopherol

Works well

What the product description says

“After 12 weeks, visibly improves facial volume, defines contours, and visibly fills fine lines by 24%”

Source: Skinceuticals

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.25%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.8%

Moisturizing

Dimethicone, Glycerin + 15 more

Works

What the product description says

“Instantly, skin is plumped and rehydrated for up to 24 hours.”

Source: Skinceuticals

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dipotassium glycyrrhizate, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, caprylyl glycol.

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~6.6–8.1%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.1–5.1%

Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~2.4–2.9%

Dipotassium glycyrrhizateKey active· HumectantEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~1.5–1.8%

Lactobacillus/soybean ferment extractKey activeEffect: MediumA fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking~1.2–1.4%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.65–1%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.2–0.4%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.25%

Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~2–2.4%

Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~1–1.2%

Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.45–0.65%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.25–0.45%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.2–0.35%

Oryza sativa extractEffect: Low, below effective doseA grain extract that helps to create a thicker product consistency. It might have some anti-oxidant properties and help attract water to the upper layer of the skin~0.2–0.4%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.2–0.4%

Exfoliation

Side benefit · Capryloyl salicylic acid

Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: capryloyl salicylic acid.

Capryloyl salicylic acidKey activeEffect: High~0.45–0.65%

Evens skin tone

Side benefit · Capryloyl salicylic acid, Dipotassium glycyrrhizate

May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: capryloyl salicylic acid, dipotassium glycyrrhizate.

Capryloyl salicylic acidKey activeEffect: Medium~0.45–0.65%

Dipotassium glycyrrhizateEffect: LowA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~1.5–1.8%

Can it cause trouble?

Irritancy

3 strong irritants: Alcohol denat., Citrus nobilis peel oil + 1 more — patch-test recommended

High risk

We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~3.2–3.9%est.

Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~2.4–2.9%est.

Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~2–2.4%est.

Capryloyl salicylic acid—High~0.45–0.65%est.

Citrus nobilis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.1–0.15%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.1%est.

Peg-20 methyl glucose sesquistearateHelps oil and water mix togetherMedium~0.35–0.6%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.

Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationMedium~0.25–0.45%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.2–0.4%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.2–0.4%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.2–0.35%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

Cheaper, or higher on efficacy

BIOTHERM Blue Therapy Accelerated Serum

CheaperHigher efficacy · 100/10063% match

$80.83

Vichy Idéalia Radiance Serum

Cheaper63% match

$39.00

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Dimethicone~6.6–8.1%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Glycerin~4.1–5.1%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Alcohol denat.~3.2–3.9%

Irritant · high

Irritation risk: High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.

Hydroxypropyl tetrahydropyrantriol~2.4–2.9%

Key activeIrritant · high

Irritation risk: High

Works for

Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol

Propylene glycol~2–2.4%

Irritant · high

Irritation risk: High

Works for

Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol

Polyglyceryl-4 caprate~1.7–2.1%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-4 caprate

Dipotassium glycyrrhizate~1.5–1.8%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Lactobacillus/soybean ferment extract~1.2–1.4%

Key active

Irritation risk: Low

Works for

Moisturizing

A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking

More about Lactobacillus/soybean ferment extract

Polysilicone-11~1–1.2%

Formula

Irritation risk: Low

Works for

MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11

Sodium hyaluronate~0.65–1%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Sodium hydroxide~0.55–0.85%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Tocopherol~0.5–0.8%

Formula

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Phenoxyethanol~0.45–0.7%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Capryloyl salicylic acid~0.45–0.65%

Key activeIrritant · high

Irritation risk: High

Works for

ExfoliationEvens skin toneAnti-blemish

More about Capryloyl salicylic acid

Octyldodecanol~0.45–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol

Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone~0.45–0.7%

Formula

Irritation risk: Low

Works for

Cleansing

More about Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone

Ammonium polyacryloyldimethyl taurate~0.35–0.6%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Ammonium polyacryloyldimethyl taurate

Peg-20 methyl glucose sesquistearate~0.35–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Peg-20 methyl glucose sesquistearate

Caprylyl glycol~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Xanthan gum~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Trisodium ethylenediamine disuccinate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Used to improve stability of the formulation

More about Trisodium ethylenediamine disuccinate

Sodium acetylated hyaluronate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Dextrin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Acrylates/c10-30 alkyl acrylate crosspolymer~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Oryza sativa extract~0.2–0.4%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

A grain extract that helps to create a thicker product consistency. It might have some anti-oxidant properties and help attract water to the upper layer of the skin

More about Oryza sativa extract

Caprylic/capric triglyceride~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Adenosine~0.15–0.25%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Pentylene glycol~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Citrus nobilis peel oil~0.1–0.15%

Irritant · high

Irritation risk: High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus nobilis peel oil

Limonene~0.05–0.1%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.1–0.15%

Formula

Irritation risk: Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate

Ingredient list view

Water, Dimethicone, Glycerin, Alcohol denat., Hydroxypropyl tetrahydropyrantriol, Propylene glycol, Polyglyceryl-4 caprate, Dipotassium glycyrrhizate, Lactobacillus/soybean ferment extract, Polysilicone-11, Sodium hyaluronate, Sodium hydroxide, Tocopherol, Phenoxyethanol, Capryloyl salicylic acid, Octyldodecanol, Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone, Ammonium polyacryloyldimethyl taurate, Peg-20 methyl glucose sesquistearate, Caprylyl glycol, Xanthan gum, Trisodium ethylenediamine disuccinate, Sodium acetylated hyaluronate, Dextrin, Acrylates/c10-30 alkyl acrylate crosspolymer, Oryza sativa extract, Caprylic/capric triglyceride, Adenosine, Pentylene glycol, Citrus nobilis peel oil, Limonene, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate

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Skinceuticals

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	SkinCeuticalsHyaluronic Acid Intensifier Multi-GlycanYOUR PRODUCT	SKINH.A. Intensifier Serum	BIOTHERMBlue Therapy Accelerated Serum	VichyIdéalia Radiance Serum
Match	—	67%	63%	63%
Price	$120.00	$127.52+$7.52	$80.83−$39.17	$39.00−$81.00
Shared key ingredients	—	10 of 11	8 of 11	7 of 11
Key difference	—	Polymethylsilsesquioxane	Ascorbyl Glucoside	Hydroxyethylpiperazine Ethane Sulfonic Acid
Irritancy	High	High	High	Medium
Drying alcohol	Contains drying alcohol	Contains drying alcohol	Contains drying alcohol	Contains drying alcohol
	View product	Shop	Shop	Shop

More alternatives: L'Oréal Paris Serum Le Duo Dual Anti-Aging Serum for Wrinkles, Firmness & Radiance Kiehl's s Vital Skin-Strengthening Super Serum

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Product summary

"SkinCeuticals - Hyaluronic Acid Intensifier Multi-Glycan" is effective for: Anti-aging and Exfoliation

This product could be helpful for: Evens skin tone and Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

Adenosine 0.20% - 0.35%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Dipotassium Glycyrrhizate in this product (1.50% - 1.80%) can also further help improve the skin barrier. It might be able to calm down inflammation and reduce sensitivity. Dipotassium Glycyrrhizate is an active compound from the licorice root.
Humectants (sodium acetylated hyaluronate 0.25% - 0.45%, sodium hyaluronate 0.65% - 1.00%, dipotassium glycyrrhizate 1.50% - 1.80% and glycerin 4.10% - 5.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.