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SkinCeuticals AGE Interrupter
SkinCeuticals

SkinCeuticals AGE Interrupter

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Adenosine, Butyrospermum parkii butter + 1 more
Works well
What the product description says
“This potent treatment works to correct by targeting the visible signs of ageing, like laxity, wrinkling, and dullness, that are caused by a decline in collagen and glycation.”
Source: Face the future

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.45–0.7%
Moisturizing
Panthenol, Hydroxypropyl tetrahydropyrantriol + 17 more
Works well
What the product description says
“The formula effectively smooths out fine lines, deep wrinkles, and location-specific creases like nasolabial folds, whilst delivering rich hydration and leaving behind a satin finish.”
Source: Face the future

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, caprylyl glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.5–0.75%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~4.9–6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.5–0.7%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~3–3.7%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.4–3%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~1.4–1.8%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.2–1.5%
Arachidyl alcohol· EmollientEffect: LowUsed to soften the upper layer of the skin and create a thicker product consistency~0.7–1.05%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.45–0.65%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.35–0.65%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.5%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.2–0.4%
Isononyl isononanoateEffect: Low, below effective doseForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~0.45–0.65%
Myristyl myristateUnder-dosedAn emollient. Is not recommended for acne-prone skin as it can be comedogenic~0.65–0.95%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.45–0.7%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.55%
Anti-oxidation
Side benefit · Glycyrrhetinic acid, Butyrospermum parkii butter + 3 more
Works well

This product contains antioxidants (glycyrrhetinic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Glycyrrhetinic acidKey activeEffect: HighActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%
Vaccinium myrtillus fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking~0.2–0.4%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Punica granatum fruit extractEffect: LowA fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties~0.15–0.25%
Evens skin tone
Side benefit the brand mentions · Glycyrrhetinic acid, Niacinamide
May help
What the product description says
“SkinCeuticals AGE Interrupter is specifically formulated to target visible signs of ageing such as fine lines, wrinkles, uneven skin texture and dryness creating a more youthful and revitalised complexion.”
Source: Face the future

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycyrrhetinic acid.

Glycyrrhetinic acidKey activeEffect: MediumActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation~0.25–0.45%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.45–0.7%

Can it cause trouble?

Irritancy
4 strong irritants: Parfum, Limonene + 2 more — patch-test recommended
High risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~4.9–6%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~3–3.7%est.
Oleyl alcoholUsed as a fragranceHigh~0.95–1.15%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.
Punica granatum fruit extractA fruit extract that is used to add a fragrance to the product. It might have some antioxidant propertiesHigh~0.15–0.25%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.2%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.1–0.2%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
Hydroxyethylpiperazine ethane sulfonic acidUsed to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical productsMedium~1.6–2%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.2–1.5%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenicMedium~0.65–0.95%est.
Pentaerythrityl tetraisostearateUsed to create a thicker product consistencyMedium~0.3–0.6%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.5%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Myristic acidHelps oil and water mix together. Could be comedogenicMedium~0.3–0.55%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.55%est.
Glycyrrhetinic acidActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentationMedium~0.25–0.45%est.
Vaccinium myrtillus fruit extractA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lackingMedium~0.2–0.4%est.
Potassium hydroxideUsed to adjust the pH level of productsMedium~0.2–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2–2.4%est.
Oleyl alcoholUsed as a fragrance3/5~0.95–1.15%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenic3/5~0.65–0.95%est.
Myristic acidHelps oil and water mix together. Could be comedogenic3/5~0.3–0.55%est.
Alternatives
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Hydroxypropyl tetrahydropyrantriol~4.9–6%
Key activeIrritant · high
Irritation risk
High
Works for
Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Propylene glycol~3–3.7%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Stearic acid~2.4–3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Butyrospermum parkii butter~2–2.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Hydroxyethylpiperazine ethane sulfonic acid~1.6–2%
Irritant · medium
Irritation risk
Medium
Works for
Exfoliation

Used to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical products

More about Hydroxyethylpiperazine ethane sulfonic acid
Palmitic acid~1.4–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Pentylene glycol~1.2–1.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Oleyl alcohol~0.95–1.15%
Comedogenic 3/5Irritant · high
Irritation risk
High
Comedogenicity
3/5

Used as a fragrance

More about Oleyl alcohol
Arachidyl alcohol~0.7–1.05%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to soften the upper layer of the skin and create a thicker product consistency

More about Arachidyl alcohol
Myristyl myristate~0.65–0.95%
Under-dosedComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Is not recommended for acne-prone skin as it can be comedogenic

More about Myristyl myristate
Panthenol~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Niacinamide~0.45–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Dimethicone~0.5–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Isononyl isononanoate~0.45–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone~0.45–0.65%
Formula
Irritation risk
Low
Works for
Cleansing
More about Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone
Glyceryl stearate~0.45–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Candelilla cera~0.4–0.6%
Formula
Irritation risk
Low
More about Candelilla cera
Behenyl alcohol~0.35–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Peg-100 stearate~0.4–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Sodium polyacrylate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Pentaerythrityl tetraisostearate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency

More about Pentaerythrityl tetraisostearate
4-t-butylcyclohexanol~0.25–0.45%
Formula
Irritation risk
Low
More about 4-t-butylcyclohexanol
Arachidyl glucoside~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Arachidyl glucoside
Caprylyl glycol~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Xanthan gum~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Myristic acid~0.3–0.55%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Cleansing

Helps oil and water mix together. Could be comedogenic

More about Myristic acid
Caprylic/capric triglyceride~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycyrrhetinic acid~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-oxidationEvens skin tone

Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation

More about Glycyrrhetinic acid
Parfum~0.2–0.4%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sorbitol~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Vaccinium myrtillus fruit extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking

More about Vaccinium myrtillus fruit extract
Potassium hydroxide~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to adjust the pH level of products

More about Potassium hydroxide
Adenosine~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Citric acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Punica granatum fruit extract~0.15–0.25%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties

More about Punica granatum fruit extract
Limonene~0.1–0.2%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Coumarin~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.1–0.15%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Ingredient list view

Water, Hydroxypropyl tetrahydropyrantriol, Glycerin, Propylene glycol, Stearic acid, Butyrospermum parkii butter, Hydroxyethylpiperazine ethane sulfonic acid, Palmitic acid, Pentylene glycol, Oleyl alcohol, Arachidyl alcohol, Myristyl myristate, Panthenol, Niacinamide, Dimethicone, Isononyl isononanoate, Bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone, Glyceryl stearate, Candelilla cera, Behenyl alcohol, Peg-100 stearate, Sodium polyacrylate, Pentaerythrityl tetraisostearate, 4-t-butylcyclohexanol, Arachidyl glucoside, Caprylyl glycol, Xanthan gum, Chlorphenesin, Myristic acid, Caprylic/capric triglyceride, Glycyrrhetinic acid, Parfum, Sorbitol, Vaccinium myrtillus fruit extract, Potassium hydroxide, Adenosine, Citric acid, Punica granatum fruit extract, Limonene, Coumarin, Linalool, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SkinCeuticalsAGE InterrupterYOUR PRODUCTCiracleAnti-Redness K CreamHeimishBlack Rose Hydra Plumping Sorbet CreamIt CosmeticsConfidence in a Cream Barrier Boost Skin Barrier Repair Moisturizer
Match—91%91%90%
Price—$23.10$19.97$49.00
Shared key ingredients—7 of 128 of 126 of 12
Key difference—Madecassic AcidCopper Tripeptide-1Acetyl Dipeptide-1 Cetyl Ester
Irritancy High Medium Medium Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 23 studies and safety reviews.

  1. 1
    A Compensating Skin Care Complex Containing Pro-xylane in Menopausal Women: Results from a Multicentre, Evaluator-blinded, Randomized Studyingentaconnect.com
  2. 2
    Synthesis of Pro-XylaneTM: A new biologically active C-glycoside in aqueous mediasciencedirect.com
  3. 3
    First case of contact dermatitis caused by hydroxypropyl tetrahydropyrantriol used in an anti-ageing creamsemanticscholar.org
  4. 4
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  5. 5
    Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
  6. 6
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
SkinCeuticals AGE Interrupter
SkinCeuticalsAGE Interrupter
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