SkinCeuticals Advanced RGN-6 Regenerative Cream
Works for
3 of 3 advertised claims delivered
Moisturizing16 ingredients credited for this claimStrong support
“Boosts skin barrier repair and thickness”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-9, niacinamide
Evens skin tone1 ingredient credited for this claimStrong support
“Reduces visible redness, post-acne marks, dark spots, and wrinkles with daily use”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Anti-aging5 ingredients credited for this claimStrong support
“Advanced RGN-6 regenerative cream reverses 6 signs of aging and skin tone damage for visibly rejuvenated skin starting in 1 week.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-9.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Anti-blemishNot advertised by the brand · 1 ingredient credited for this claimStrong support
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Can it cause trouble?
Irritancy6 flagged ingredientsLow risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
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Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Glycerin~4.6–6.9%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinEthyl oleate~3.7–5.6%
- Irritation risk
- Medium
Ethyl oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol. It derives from an oleic acid. In skincare, it is used to soften the upper layer of the skin, improve the product texture and smell
More about Ethyl oleateNiacinamide~2.7–4.1%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideSqualane~2.1–3.2%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneC12-16 alcohols~1.7–2.5%
- Irritation risk
- Medium
Helps soften the upper layer of the skin and improve the product's texture
More about C12-16 alcoholsGlyceryl stearate citrate~1.4–2.1%
- Irritation risk
- Low
Helps oil and water mix together while softening the upper layer of the skin
More about Glyceryl stearate citrateButyrospermum parkii butter~1.3–2%
- Irritation risk
- Low
- Comedogenicity
- 3/5
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
More about Butyrospermum parkii butterMaltodextrin~1.1–1.6%
- Irritation risk
- Low
Used to stabilize the product formulation and can help absorb oil
More about MaltodextrinAmmonium polyacryloyldimethyl taurate~0.8–1.25%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Ammonium polyacryloyldimethyl tauratePhenoxyethanol~0.5–1%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolDimethicone~0.45–1.05%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconePalmitic acid~0.4–0.95%
- Irritation risk
- Low
An emollient that is naturally present in skin and helps soften it
More about Palmitic acidHydrogenated lecithin~0.35–0.8%
- Irritation risk
- Low
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
More about Hydrogenated lecithinCetyl alcohol~0.35–0.8%
- Irritation risk
- Low
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
More about Cetyl alcoholCeratonia siliqua seed extract~0.3–0.7%
- Irritation risk
- Low
Caprylyl glycol~0.3–0.7%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycol2-oleamido-1,3-octadecanediol~0.2–0.7%
- Irritation risk
- Low
Helps soften the upper layer of the skin and slow down the water loss over time
More about 2-oleamido-1,3-octadecanediolEctoin~0.15–0.6%
- Irritation risk
- Low
Softens the upper layer of the skin and can support skin barrier function
More about EctoinTocopherol~0.15–0.5%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolEperua falcata bark extract~0.1–0.5%
- Irritation risk
- Low
Xanthan gum~0.1–0.5%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumEthylhexylglycerin~0.1–0.4%
Phytic acid~0.1–0.4%
- Irritation risk
- Medium
An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics
More about Phytic acidAdenosine~0.1–0.3%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineSodium hydroxide~0.05–0.25%
Sodium benzoate~0.05–0.2%
Acetyl tetrapeptide-9~0.05–0.15%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl tetrapeptide-9Citric acid~0.01–0.05%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidIngredient list view
Water, Glycerin, Ethyl oleate, Niacinamide, Squalane, C12-16 alcohols, Glyceryl stearate citrate, Butyrospermum parkii butter, Maltodextrin, Ammonium polyacryloyldimethyl taurate, Phenoxyethanol, Dimethicone, Palmitic acid, Hydrogenated lecithin, Cetyl alcohol, Ceratonia siliqua seed extract, Caprylyl glycol, 2-oleamido-1,3-octadecanediol, Ectoin, Tocopherol, Eperua falcata bark extract, Xanthan gum, Ethylhexylglycerin, Phytic acid, Adenosine, Sodium hydroxide, Sodium benzoate, Acetyl tetrapeptide-9, Citric acid
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| SkinCeuticalsAdvanced RGN-6 Regenerative CreamYOUR PRODUCT | It CosmeticsConfidence in a Cream Barrier Boost Skin Barrier Repair Moisturizer | LancômeAbsolue Longevity MD Anticipate The Cream | Doctor Rogers RestoreRestore Face Cream | |
|---|---|---|---|---|
| Match | — | 88% | 84% | 82% |
| Price | $195.00 | $49.00−$146.00 | $133.86−$61.14 | $72.00−$123.00 |
| Shared key ingredients | — | 7 of 9 | 8 of 9 | 5 of 9 |
| Key difference | — | Acetyl Dipeptide-1 Cetyl Ester | Salicylic Acid | Centella Asiatica Extract |
| Irritancy | Low | Low | High | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 12 studies and safety reviews.
- 1
- 2
- 3
- 4
- 5
- 6Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
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