SkinCeuticals A.G.E. Interrupter

SkinCeuticals A.G.E. Interrupter

Efficacy75/100IrritancyHigh

Works for

Moisturizing
Salicyloyl phytosphingosine, Dimethicone + 6 more
Works well
What the product description says
“Restores water and nutrients to improve the look of skin firmness”
Source: Skinceuticals

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, propylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, ethylhexyl hydroxystearate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: salicyloyl phytosphingosine

Salicyloyl phytosphingosineHero· HumectantEffect: HighHelps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking~0.2–0.75%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.7–5.5%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~2.7–4.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.5–2.3%
Ethylhexyl hydroxystearateKey active· Emollient, OcclusiveEffect: HighHelps soften the upper layer of the skin and reduce water loss from it~0.4–0.9%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~4.5–6.7%
Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~2.1–3.2%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~1.8–2.7%
Anti-aging
Salicyloyl phytosphingosine
Not delivered
What the product description says
“High-concentration anti-wrinkle cream formulated to improve the visible signs of aging caused by advanced glycation end-products (A.G.E.)”
Source: Skinceuticals

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.This ingredient - salicyloyl phytosphingosine - could be helpful for preventing or repairing signs of aging in theory, but there is no evidence that it actually works.

Salicyloyl phytosphingosineEffect: LowHelps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking~0.2–0.75%

Can it cause trouble?

Irritancy
3 strong irritants: Parfum, Butylphenyl methylpropional + 1 more — patch-test recommended
High risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~4.5–6.7%est.
Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~2.7–4.1%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.2%est.
Butylphenyl methylpropionalA fragrance. Can trigger allergic reactions and be irritatingHigh~0.05–0.15%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.05–0.1%est.
Dimethicone/peg-10/15 crosspolymerHelps oil and water mix togetherMedium~1.1–1.6%est.
Aluminum starch octenylsuccinateUsed to thicken the product's consistencyMedium~0.85–1.25%est.
Acrylates copolymerUsed to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistencyMedium~0.15–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.3%est.
Vaccinium myrtillus fruit extractA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lackingMedium~0.1–0.3%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Propylene glycol~4.5–6.7%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Dimethicone~3.7–5.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Hydroxypropyl tetrahydropyrantriol~2.7–4.1%
Key activeIrritant · high
Irritation risk
High
Works for
Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol
Cyclohexasiloxane~2.1–3.2%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Isohexadecane~1.8–2.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Glycerin~1.5–2.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Synthetic wax~1.3–1.9%
Formula
Irritation risk
Low

Used to stabilize product formulations and thicken product consistency

More about Synthetic wax
Dimethicone/peg-10/15 crosspolymer~1.1–1.6%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Dimethicone/peg-10/15 crosspolymer
Aluminum starch octenylsuccinate~0.85–1.25%
Irritant · medium
Irritation risk
Medium

Used to thicken the product's consistency

More about Aluminum starch octenylsuccinate
Ci 77163~0.55–1.25%
Formula
Irritation risk
Low

Colorant

More about Ci 77163
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Magnesium sulfate~0.45–1.05%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Magnesium sulfate
Ethylhexyl hydroxystearate~0.4–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from it

More about Ethylhexyl hydroxystearate
Salicyloyl phytosphingosine~0.2–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

Helps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking

More about Salicyloyl phytosphingosine
Acrylates copolymer~0.15–0.65%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistency

More about Acrylates copolymer
Methylparaben~0.15–0.3%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Ethylparaben~0.1–0.35%
Formula
Irritation risk
Low

A preservative

More about Ethylparaben
Disodium edta~0.1–0.3%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Vaccinium myrtillus fruit extract~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking

More about Vaccinium myrtillus fruit extract
Parfum~0.05–0.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Butylphenyl methylpropional~0.05–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can trigger allergic reactions and be irritating

More about Butylphenyl methylpropional
Coumarin~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Ingredient list view

Water, Propylene glycol, Dimethicone, Hydroxypropyl tetrahydropyrantriol, Cyclohexasiloxane, Isohexadecane, Glycerin, Synthetic wax, Dimethicone/peg-10/15 crosspolymer, Aluminum starch octenylsuccinate, Ci 77163, Phenoxyethanol, Magnesium sulfate, Ethylhexyl hydroxystearate, Salicyloyl phytosphingosine, Acrylates copolymer, Methylparaben, Ethylparaben, Disodium edta, Vaccinium myrtillus fruit extract, Parfum, Butylphenyl methylpropional, Coumarin

Compare prices

Retailers ranked by price — lowest first.

Bluemercury
$83.97
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Dermstore1.7 fl. oz
$168.00
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Skinceuticals
$168.00
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Amazon US
Price unavailable Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SkinCeuticalsA.G.E. InterrupterYOUR PRODUCTVichyNeovadiol Post-Menopause Firming Lipid-Replenishing Night CreamLancômeGénifique Crème Youth Activating Day CreamL'Oréal ParisAnti-Wrinkle Firming Moisturizer Fragrance Free
Match—64%60%58%
Price$83.97$40.81−$43.16$96.25+$12.28$15.60−$68.37
Shared key ingredients—4 of 53 of 52 of 5
Key difference—NiacinamideAdenosineMineral Oil
Irritancy High Medium High Medium
Drying alcohol— Contains drying alcohol ——
View product Shop Shop Shop

More alternatives: Lanc\u00f4me Génifique Youth Activating Day CreamTrinny London Bounce Back

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Product summary

"SkinCeuticals - A. G. E. Interrupter" is effective for: Moisturizing

Ingredient callouts

  • Ceramides (salicyloyl phytosphingosine 0.30% - 0.75%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Humectants (salicyloyl phytosphingosine 0.30% - 0.75% and glycerin 1.50% - 2.30%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 83.97$ up to 236.25$ in the United States and for 162.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
  2. 2
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
  3. 3
  4. 4
  5. 5
  6. 6
SkinCeuticals A.G.E. Interrupter
SkinCeuticalsA.G.E. Interrupter

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As an Amazon Associate, WIMJ earns from qualifying purchases.