Sisley-Paris Sisleÿum Anti-Aging Comfort Cream

Sisley-Paris Sisleÿum Anti-Aging Comfort Cream

Efficacy100/100IrritancyHigh
Edit

Works for

2 of 2 advertised claims delivered

Anti-aging
Adenosine, Niacinamide + 2 more
Strong evidence
What the product description says
“Adenosine helps smooth wrinkles and fine lines.”
Source: Sisley

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.5–0.75%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–2.4%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.3–2.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
Moisturizing
Niacinamide, Butyrospermum parkii butter + 15 more
Strong evidence
What the product description says
“Phytosqualane moisturizes and strengthens the protective film of the epidermis.”
Source: Sisley

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: biosaccharide gum-1, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.3–2.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.5–5.5%
Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.45–0.7%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~1.2–1.4%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–2.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.6–0.9%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.8–2.1%
Biosaccharide gum-1Key active· HumectantEffect: HighHelps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin~0.55–0.85%
TricaprylinKey active· EmollientEffect: MediumAn emollient that helps soften the skin. Can increase penetration of other ingredients~6–7.4%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.5–0.75%
Lauroyl lysineKey activeEffect: MediumHelps soften the upper layer of the skin and creates a nice product texture~0.95–1.15%
Isodecyl neopentanoate· Emollient, OcclusiveEffect: LowAn emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.~3.6–4.3%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~2.6–3.1%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.45–0.7%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.4–1.7%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.75–1.1%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
Anti-blemish
Not advertised by the brand · Niacinamide
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–2.4%
Evens skin tone
Not advertised by the brand · Niacinamide, Albizia julibrissin bark extract
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: albizia julibrissin bark extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–2.4%
Albizia julibrissin bark extractEffect: LowA plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missing~0.45–0.7%

Can it cause trouble?

Irritancy
9 strong irritants: Rosmarinus officinalis leaf oil, Thymus mastichina flower oil + 7 more — patch-test recommended
High risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Combretum micranthum leaf extractA plant extract that might have some anti-oxidant propertiesHigh~0.5–0.8%est.
Albizia julibrissin bark extractA plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missingHigh~0.45–0.7%est.
Rosmarinus officinalis leaf oilA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skinHigh~0.45–0.65%est.
Thymus mastichina flower oil—High~0.45–0.65%est.
Salvia officinalis oil—High~0.45–0.7%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.4–0.65%est.
Camphor—High~0.45–0.7%est.
LinaloolA fragrance. Can be irritatingHigh~0.35–0.65%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.35–0.65%est.
Citrus limon peel oilA highly irritating fragranceHigh~0.2–0.35%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~2.6–3.1%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.4–1.7%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.75–1.1%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.6–0.95%est.
EthylhexylglycerinA preservativeMedium~0.45–0.7%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.5–0.75%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.45–0.7%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.45–0.7%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.45–0.7%est.
Sorbic acidA preservativeMedium~0.3–0.6%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~2.6–3.1%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.3–2.8%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.45–0.7%est.
Edit

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Write a review · ~30s

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Tricaprylin~6–7.4%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin. Can increase penetration of other ingredients

More about Tricaprylin
Glycerin~4.5–5.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Isodecyl neopentanoate~3.6–4.3%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.

More about Isodecyl neopentanoate
Isopropyl palmitate~2.6–3.1%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Butyrospermum parkii butter~2.3–2.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Niacinamide~2–2.4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Squalane~1.8–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Pentylene glycol~1.4–1.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Helianthus annuus seed oil~1.2–1.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Lauroyl lysine~0.95–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and creates a nice product texture

More about Lauroyl lysine
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.75–1.1%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Glyceryl stearate~0.75–1.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.75–1.1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Tocopheryl acetate~0.6–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Prunus amygdalus dulcis protein~0.6–0.9%
Formula
Sodium hyaluronate~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Biosaccharide gum-1~0.55–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin

More about Biosaccharide gum-1
Combretum micranthum leaf extract~0.5–0.8%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Combretum micranthum leaf extract
Adenosine~0.5–0.75%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Salix alba leaf extract~0.5–0.7%
Formula
Albizia julibrissin bark extract~0.45–0.7%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-inflammatory

A plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missing

More about Albizia julibrissin bark extract
Orthosiphon stamineus extract~0.45–0.7%
Formula
Isodonis japonicus leaf/stalk extract~0.45–0.7%
Formula
Rosmarinus officinalis leaf oil~0.45–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAntibacterial

A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin

More about Rosmarinus officinalis leaf oil
Thymus mastichina flower oil~0.45–0.65%
Irritant · high
Salvia officinalis oil~0.45–0.7%
Irritant · high
Maltodextrin~0.45–0.7%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Butylene glycol~0.45–0.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Xanthan gum~0.45–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ethylhexylglycerin~0.45–0.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
C18-21 alkane~0.45–0.7%
Formula
Irritation risk
Low
More about C18-21 alkane
Polysorbate 60~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sorbitan isostearate~0.5–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Citric acid~0.45–0.7%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium hydroxide~0.45–0.7%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium citrate~0.45–0.7%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Glycine soja oil~0.45–0.7%
Key activeComedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Parfum~0.4–0.65%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sorbic acid~0.3–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.5–0.7%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Tocopherol~0.45–0.7%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Pinene~0.45–0.7%
Formula
Irritation risk
Low
More about Pinene
Camphor~0.45–0.7%
Irritant · high
Irritation risk
High
More about Camphor
Linalool~0.35–0.65%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Limonene~0.35–0.65%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Beta-caryophyllene~0.35–0.6%
Formula
Tetramethyl acetyloctahydronaphthalenes~0.3–0.6%
Formula
Terpineol~0.3–0.55%
Formula
Irritation risk
Low
More about Terpineol
Citrus aurantium bergamia peel oil~0.3–0.6%
Irritant · high
Linalyl acetate~0.3–0.55%
Formula
Citrus limon peel oil~0.2–0.35%
Irritant · high
Irritation risk
High

A highly irritating fragrance

More about Citrus limon peel oil
Pogostemon cablin oil~0.15–0.3%
Formula
Alpha-terpinene~0.2–0.35%
Formula
Terpinolene~0.15–0.3%
Formula
Irritation risk
Low
More about Terpinolene
Acetyl cedrene~0.1–0.2%
Formula
Irritation risk
Low
More about Acetyl cedrene
Ingredient list view

Water, Tricaprylin, Glycerin, Isodecyl neopentanoate, Isopropyl palmitate, Butyrospermum parkii butter, Niacinamide, Squalane, Pentylene glycol, Helianthus annuus seed oil, Lauroyl lysine, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Glyceryl stearate, Peg-100 stearate, Tocopheryl acetate, Prunus amygdalus dulcis protein, Sodium hyaluronate, Biosaccharide gum-1, Combretum micranthum leaf extract, Adenosine, Salix alba leaf extract, Albizia julibrissin bark extract, Orthosiphon stamineus extract, Isodonis japonicus leaf/stalk extract, Rosmarinus officinalis leaf oil, Thymus mastichina flower oil, Salvia officinalis oil, Maltodextrin, Butylene glycol, Xanthan gum, Ethylhexylglycerin, C18-21 alkane, Polysorbate 60, Sorbitan isostearate, Citric acid, Sodium hydroxide, Sodium citrate, Glycine soja oil, Parfum, Sorbic acid, Sodium benzoate, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Tocopherol, Pinene, Camphor, Linalool, Limonene, Beta-caryophyllene, Tetramethyl acetyloctahydronaphthalenes, Terpineol, Citrus aurantium bergamia peel oil, Linalyl acetate, Citrus limon peel oil, Pogostemon cablin oil, Alpha-terpinene, Terpinolene, Acetyl cedrene

Compare prices

Retailers ranked by price — lowest first.

Sisley
$370.00
Buy

Affiliate links · prices updated regularly

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Sisley-ParisSisleÿum Anti-Aging Comfort CreamYOUR PRODUCTLa MuseDaily Essentials Regenerating CreamLumeneNordic Ageless [AJATON] Radiant Youth Night CreamAvèneRetrinal 0.1% Intensive Multi-Corrective Cream
Match—92%92%92%
Price$370.00$27.60−$342.40$56.54−$313.46$68.00−$302.00
Shared key ingredients—7 of 107 of 107 of 10
Key difference—Ceramide NpCopper Heptapeptide-14 PantothenateRetinal
Irritancy High Medium Medium Medium
Drying alcohol— Contains drying alcohol ——
View product Shop Shop Shop
Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
Sisley-Paris Sisleÿum Anti-Aging Comfort Cream
Sisley-ParisSisleÿum Anti-Aging Comfort Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.