Shiseido Vital Perfection LiftDefine Radiance Serum
Works for
Evens skin tonePotassium methoxysalicylate, Glucosamine hcl + 1 moreWorks well
“Infused with 4MSK, this dewy serum brightens your skin and visibly helps reduce sagging, wrinkles and dark spots.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: potassium methoxysalicylate
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glucosamine hcl.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
MoisturizingDimethicone, Maltitol + 14 moreWorks
“Key Benefits Powered by Re Neura Technology++TM which helps to reawaken skin’s internal sensory signals, declining with age, while enhancing effects that fight against signs of aging.Contains Watercress Extract known to promote skin’s natural production of collagen.Features KURENAI-Tru Lift Complex with safflower extract to help to promote firmness.24-hour lasting moisture UK200031662”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glucosamine hcl, inositol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, peg-10 dimethicone.
Anti-agingGlucosamine hcl, Camellia sinensis leaf extract + 1 moreNot delivered
“Infused with 4MSK, this dewy serum brightens your skin and visibly helps reduce sagging, wrinkles and dark spots.”
Effective ingredients missing or their concentration is too low.
Can it cause trouble?
Irritancy11 strong irritants: Parfum, Rosa damascena flower water + 9 more — patch-test recommendedHigh risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Dipropylene glycol~6.7–8.2%
- Irritation risk
- Low
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
More about Dipropylene glycolDimethicone~4.3–5.2%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeButylene glycol~3.1–3.8%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolBehenyl alcohol~2.5–3%
- Irritation risk
- Low
Non-drying alcohol that helps water and oil mix together. Also serves as an emollient
More about Behenyl alcoholMaltitol~1.9–2.3%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin
More about MaltitolTriethylhexanoin~1.4–1.7%
- Irritation risk
- Medium
Helps soften the upper layer of the skin
More about TriethylhexanoinPotassium methoxysalicylate~1.4–1.7%
- Irritation risk
- Medium
Can help reduce hyperpigmentation
More about Potassium methoxysalicylatePolyvinyl alcohol~1.2–1.5%
Peg/ppg-14/7 dimethyl ether~1–1.2%
- Irritation risk
- Low
An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss
More about Peg/ppg-14/7 dimethyl etherPhenoxyethanol~0.6–0.95%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolTrimethylsiloxysilicate~0.55–0.8%
- Irritation risk
- Low
A type of silicone that helps create a nice product consistency and support the delivery of other ingredients
More about TrimethylsiloxysilicateBatyl alcohol~0.5–0.75%
- Irritation risk
- Low
Non-drying alcohol. Used to stabilize other ingredients and is an emollient
More about Batyl alcoholPeg-60 glyceryl isostearate~0.4–0.65%
Peg-10 dimethicone~0.45–0.65%
- Irritation risk
- Low
A silicone that works to soften the upper layer of the skin and reduce its water loss
More about Peg-10 dimethiconeParfum~0.3–0.6%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumPhytosteryl/octyldodecyl lauroyl glutamate~0.4–0.65%
- Irritation risk
- Low
A mix of amino acids and plant-based lipids. Helps to soften the upper layer of the skin and reduce water loss over time
More about Phytosteryl/octyldodecyl lauroyl glutamateDisodium edta~0.3–0.55%
Myristyl myristate~0.3–0.55%
- Irritation risk
- Medium
- Comedogenicity
- 3/5
An emollient. Is not recommended for acne-prone skin as it can be comedogenic
More about Myristyl myristateTocopheryl acetate~0.25–0.45%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateRosa damascena flower water~0.2–0.4%
- Irritation risk
- High
Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating
More about Rosa damascena flower waterPotassium hydroxide~0.2–0.4%
2-o-ethyl ascorbic acid~0.2–0.35%
- Irritation risk
- Low
Alcohol~0.2–0.35%
- Irritation risk
- High
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
More about AlcoholCaffeine~0.2–0.35%
- Irritation risk
- Medium
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
More about CaffeineCitric acid~0.2–0.35%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidLavandula angustifolia oil~0.2–0.35%
- Irritation risk
- High
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
More about Lavandula angustifolia oilSodium metaphosphate~0.2–0.4%
Ppg-3 dipivalate~0.2–0.4%
Limonene~0.2–0.35%
- Irritation risk
- High
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
More about LimoneneHexyl cinnamal~0.2–0.35%
Linalool~0.2–0.35%
Tocopherol~0.2–0.4%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolGlucosamine hcl~0.2–0.35%
- Irritation risk
- Low
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
More about Glucosamine hclCitronellol~0.2–0.35%
Lilium candidum bulb extract~0.2–0.35%
- Irritation risk
- Low
Sodium metabisulfite~0.1–0.2%
Angelica acutiloba root extract~0.2–0.35%
- Irritation risk
- Low
Angelica keiskei leaf/stem extract~0.2–0.35%
- Irritation risk
- High
A fragrant plant extract. Might have some anti-oxidant properties. Can be irritating
More about Angelica keiskei leaf/stem extractOlea europaea leaf extract~0.15–0.3%
- Irritation risk
- Medium
A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing
More about Olea europaea leaf extractLamium album flower/leaf/stem extract~0.2–0.35%
- Irritation risk
- Low
Camellia sinensis leaf extract~0.2–0.35%
- Irritation risk
- Low
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
More about Camellia sinensis leaf extractInositol~0.2–0.35%
Carthamus tinctorius flower extract~0.15–0.3%
- Irritation risk
- Low
Iron oxides~0.2–0.35%
- Irritation risk
- Low
An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear
More about Iron oxidesCi 77492~0.2–0.35%
Ziziphus jujuba fruit extract~0.2–0.35%
- Irritation risk
- Low
Iron oxides~0.15–0.3%
- Irritation risk
- Low
An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear
More about Iron oxidesCi 77491~0.15–0.3%
- Irritation risk
- Low
A red colorant made of iron oxide. Typically is not irritating
More about Ci 77491Rosmarinus officinalis leaf extract~0.15–0.3%
- Irritation risk
- High
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
More about Rosmarinus officinalis leaf extractCinnamomum cassia bark extract~0.15–0.25%
Bupleurum falcatum root extract~0.1–0.2%
- Irritation risk
- High
A plant extract that might help to attract water to the upper layer of the skin, but it is not well studied. It can be irritating
More about Bupleurum falcatum root extractIngredient list view
Water, Dipropylene glycol, Dimethicone, Unknown, Butylene glycol, Behenyl alcohol, Maltitol, Triethylhexanoin, Potassium methoxysalicylate, Polyvinyl alcohol, Peg/ppg-14/7 dimethyl ether, Phenoxyethanol, Trimethylsiloxysilicate, Batyl alcohol, Unknown, Peg-60 glyceryl isostearate, Peg-10 dimethicone, Parfum, Phytosteryl/octyldodecyl lauroyl glutamate, Disodium edta, Myristyl myristate, Tocopheryl acetate, Rosa damascena flower water, Potassium hydroxide, Unknown, 2-o-ethyl ascorbic acid, Alcohol, Caffeine, Citric acid, Lavandula angustifolia oil, Sodium metaphosphate, Ppg-3 dipivalate, Limonene, Hexyl cinnamal, Linalool, Tocopherol, Glucosamine hcl, Citronellol, Lilium candidum bulb extract, Sodium metabisulfite, Angelica acutiloba root extract, Angelica keiskei leaf/stem extract, Olea europaea leaf extract, Lamium album flower/leaf/stem extract, Camellia sinensis leaf extract, Inositol, Carthamus tinctorius flower extract, Iron oxides, Ci 77492, Ziziphus jujuba fruit extract, Iron oxides, Ci 77491, Rosmarinus officinalis leaf extract, Cinnamomum cassia bark extract, Bupleurum falcatum root extract
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| ShiseidoVital Perfection LiftDefine Radiance SerumYOUR PRODUCT | Institut EsthedermExcellage Firming Face Serum | innisfreeIntensified serum | the SKIN HOUSEWrinkle Supreme Serum | |
|---|---|---|---|---|
| Match | — | 35% | 35% | 35% |
| Price | $138.00 | $66.92−$71.08 | — | $14.11−$123.89 |
| Shared key ingredients | — | 4 of 12 | 3 of 12 | 3 of 12 |
| Key difference | — | Niacinamide | Adenosine | Adenosine |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | Contains drying alcohol | Contains drying alcohol | — | Contains drying alcohol |
| View product | Shop | Shop | Shop |
More alternatives: Clinique Even Better Clinical Dark Spot Clearing Serum with Vitamin CTHE FACE SHOP Yehwadam Heaven Grade Ginseng Rejuvenating Serum
Product summary
"Shiseido - Vital Perfection LiftDefine Radiance Serum" is effective for: Evens skin tone
This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Humectants (inositol 0.20% - 0.35% and glucosamine hcl 0.20% - 0.35%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails from 88.84£ up to 1450.00£ in the United Kingdom, for 159.86A$ in Australia, from 138.00$ up to 237.90$ in the United States and for 1300.00HK$ in Hong Kong.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.
- 1
- 2Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 3
- 4
- 5
- 6
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