ROUND LAB

ROUND LAB Sérum anti-taches Vita Niacinamide

Name: ROUND LAB - Sérum anti-taches Vita Niacinamide
Brand: ROUND LAB

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Evens skin tone

Niacinamide, Tranexamic acid + 2 more

Works well

What the product description says

“Sérum anti-taches Vita Niacinamide”

Source: Stylevana

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide, tranexamic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: 3-o-ethyl ascorbic acid.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–6.6%

Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~0.8–1.2%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.15–0.55%

3-o-ethyl ascorbic acidKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.5%

Anti-blemish

Niacinamide, Centella asiatica extract + 1 more

Works well

What the product description says

“Contains Triple Vita Activer (TM) (vitamin tree water, ethyl ascorbic acid, and vitamin tree fruit extract) to provide effective blemish care without irritation.”

Source: Stylevana

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.4–6.6%

Centella asiatica extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.75%

Rosmarinus officinalis leaf extractUnder-dosedCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.15–0.65%

Anti-aging

Side benefit · Niacinamide, Centella asiatica extract + 4 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: centella asiatica extract, hydroxydecyl ubiquinone.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.75%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%

Hydroxydecyl ubiquinoneKey activeEffect: MediumAn analogue of coenzyme Q10 that has a lower molecular weight, which can improve its ability to penetrate the skin. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.15–0.5%

3-o-ethyl ascorbic acidEffect: LowA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.5%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.25%

Moisturizing

Side benefit · Niacinamide, Panthenol + 13 more

Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1–1.5%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.65%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.3–2%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.75%

Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.75%

Hydroxydecyl ubiquinoneKey activeEffect: HighAn analogue of coenzyme Q10 that has a lower molecular weight, which can improve its ability to penetrate the skin. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.15–0.5%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.2–4.7%

Portulaca oleracea extract· HumectantEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.2–0.8%

AgarEffect: LowPolysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skin~0.1–0.35%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.35–0.8%

Anti-oxidation

Side benefit · Centella asiatica extract, Hydroxydecyl ubiquinone + 8 more

Works well

This product contains antioxidants (glutathione, hydroxydecyl ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - 3-o-ethyl ascorbic acid, centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Hippophae rhamnoides fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking~0.45–1.1%

Portulaca oleracea extractEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.2–0.8%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%

Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.15–0.65%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.1–0.45%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.25%

Can it cause trouble?

Irritancy

1 strong irritant: Rosmarinus officinalis leaf extract

Medium risk

We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.15–0.65%est.

Chamomilla recutita extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.15–0.7%est.

3-o-ethyl ascorbic acidA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsHigh~0.15–0.5%est.

Hippophae rhamnoides waterA plant-infused water. The concentration of compounds with potential skin benefits is unlikely to be effectiveMedium~23–34%est.

1,2-hexanediolA preservativeMedium~1.3–1.9%est.

Hippophae rhamnoides fruit extractA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lackingMedium~0.45–1.1%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.3–0.75%est.

Portulaca oleracea extractA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skinMedium~0.2–0.8%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.8%est.

EthylhexylglycerinA preservativeMedium~0.15–0.65%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.15–0.55%est.

Hydroxydecyl ubiquinoneAn analogue of coenzyme Q10 that has a lower molecular weight, which can improve its ability to penetrate the skin. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergenMedium~0.15–0.5%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.15–0.65%est.

Disodium edtaStabilizes the product formulationMedium~0.1–0.45%est.

AgarPolysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skinMedium~0.1–0.35%est.

XanthophyllsA yellow colorantMedium~0.05–0.25%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Hippophae rhamnoides water~23–34%

Irritant · medium

Irritation risk: Medium

A plant-infused water. The concentration of compounds with potential skin benefits is unlikely to be effective

More about Hippophae rhamnoides water

Niacinamide~4.4–6.6%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Propanediol~4–6.1%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Butylene glycol~3.2–4.7%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~1.3–1.9%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Isopentyldiol~1.9–2.9%

Formula

Irritation risk: Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol

Water~1.5–2.2%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~1.3–2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Panthenol~1–1.5%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Tranexamic acid~0.8–1.2%

Key active

Irritation risk: Low

Works for

Evens skin toneMoisturizing

An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally

More about Tranexamic acid

Hippophae rhamnoides fruit extract~0.45–1.1%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking

More about Hippophae rhamnoides fruit extract

Centella asiatica extract~0.3–0.75%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationAnti-inflammatoryReduces rednessMoisturizingAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Portulaca oleracea extract~0.2–0.8%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizing

A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin

More about Portulaca oleracea extract

Rosmarinus officinalis leaf extract~0.15–0.65%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract

Chamomilla recutita extract~0.15–0.7%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita extract

Ficus carica extract~0.2–0.8%

Formula

Irritation risk: Low

More about Ficus carica extract

Hydrogenated lecithin~0.2–0.75%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Helianthus annuus seed oil~0.3–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Caprylic/capric triglyceride~0.35–0.8%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Ethylhexylglycerin~0.15–0.65%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Adenosine~0.15–0.6%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Glutathione~0.15–0.55%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

3-o-ethyl ascorbic acid~0.15–0.5%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-aging

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about 3-o-ethyl ascorbic acid

Hydroxydecyl ubiquinone~0.15–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationAnti-aging

An analogue of coenzyme Q10 that has a lower molecular weight, which can improve its ability to penetrate the skin. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Hydroxydecyl ubiquinone

Ceramide np~0.15–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Bisabolol~0.1–0.45%

Formula

Irritation risk: Low

Works for

Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Carbomer~0.1–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Acrylates/c10-30 alkyl acrylate crosspolymer~0.15–0.65%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Disodium edta~0.1–0.45%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Sodium polyacrylate~0.3–0.7%

Formula

Irritation risk: Low

Works for

Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate

Pvm/ma copolymer~0.15–0.55%

Formula

Irritation risk: Low

More about Pvm/ma copolymer

Cyamopsis tetragonoloba gum~0.15–0.5%

Formula

Irritation risk: Low

More about Cyamopsis tetragonoloba gum

Agar~0.1–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Polysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skin

More about Agar

Tromethamine~0.1–0.35%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Xanthan gum~0.05–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Tocopherol~0.05–0.25%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Xanthophylls~0.05–0.25%

Irritant · medium

Irritation risk: Medium

A yellow colorant

More about Xanthophylls

Ingredient list view

Hippophae rhamnoides water, Niacinamide, Propanediol, Butylene glycol, 1,2-hexanediol, Isopentyldiol, Water, Glycerin, Panthenol, Tranexamic acid, Hippophae rhamnoides fruit extract, Centella asiatica extract, Portulaca oleracea extract, Rosmarinus officinalis leaf extract, Chamomilla recutita extract, Ficus carica extract, Hydrogenated lecithin, Helianthus annuus seed oil, Caprylic/capric triglyceride, Ethylhexylglycerin, Adenosine, Glutathione, 3-o-ethyl ascorbic acid, Hydroxydecyl ubiquinone, Ceramide np, Bisabolol, Carbomer, Acrylates/c10-30 alkyl acrylate crosspolymer, Disodium edta, Sodium polyacrylate, Pvm/ma copolymer, Cyamopsis tetragonoloba gum, Agar, Tromethamine, Xanthan gum, Tocopherol, Xanthophylls

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ROUND LABSérum anti-taches Vita NiacinamideYOUR PRODUCT	Dr. AltheaVitamin C Boosting Serum	AESTURAATOBARRIER365 Hydro CERA-HA Ceramide + Hyaluronic Acid Face Serum for Skin Moisture Barrier Repair	ElishacoyKombucha Gyeol-Biome Ampoule
Match	—	89%	87%	87%
Price	—	$19.63	$34.00	$19.60
Shared key ingredients	—	9 of 14	6 of 14	5 of 14
Key difference	—	Alpha-Arbutin	Hydroxyethyl Urea	Glycine
Irritancy	Medium	Medium	Medium	Low
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"ROUND LAB - Sérum anti-taches Vita Niacinamide" is effective for: Anti-blemish, Anti-aging, Moisturizing and Evens skin tone

Ingredient callouts

A good concentration of Niacinamide (4.40% - 6.60%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
Ceramides (ceramide np 0.15% - 0.60%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Adenosine 0.15% - 0.65%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
An effective concentration of Panthenol (pro-vitamin B5) - about 1.00% - 1.50%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
Humectants (panthenol 1.00% - 1.50% and glycerin 1.30% - 2.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 39 studies and safety reviews.

1
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
2
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
3
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
4
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
5
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
6
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
7
Effect of tranexamic acid on melasma: a clinical trial with histological evaluationonlinelibrary.wiley.com
8
Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skinonlinelibrary.wiley.com
9
The amelioration effect of tranexamic acid in wrinkles induced by skin drynesssciencedirect.com
10
Efficacy and possible mechanisms of topical tranexamic acid in melasmaonlinelibrary.wiley.com
11
Abundance of active ingredients in sea-buckthorn oilncbi.nlm.nih.gov
12
Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
13
Centella asiatica in cosmetologyncbi.nlm.nih.gov
14
Triterpene Composition and Bioactivities of Centella asiatica mdpi.com
15
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Contact dermatitis due to Madecassolonlinelibrary.wiley.com
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Portulaca oleracea (purslane)mdedge.com
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Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responsesliebertpub.com
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Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
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Antioxidant Ability and Stability Studies of 3-O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitorncbi.nlm.nih.gov
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Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
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α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net
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