Prequel RETINAL RENEW

Prequel RETINAL RENEW

Efficacy87/100IrritancyMedium

Works for

Anti-aging
Retinal, Centella asiatica leaf extract + 1 more
Works well
What the product description says
“Formulated with a highly stabilized retinaldehyde to visibly reduce fine lines and wrinkles, smooth texture, and even tone.”
Source: Prequel

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: centella asiatica leaf extract.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.3–2%
Centella asiatica leaf extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.~1–1.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.85%
Moisturizing
Glycerin, Dimethicone + 11 more
Works
What the product description says
“An advanced retinaldehyde gel that supports skin renewal and firmness while maintaining the skin barrier.”
Source: Prequel

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, caprylyl glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, simmondsia chinensis seed oil.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–5.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.7–4.1%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~2.1–3.1%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~1.2–1.8%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.6–1.4%
Helianthus annuus extractKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.4–1%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.35–0.8%
Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~0.3–0.75%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.2–0.75%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.2–0.7%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.3%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.85%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.35–0.8%
Evens skin tone
Side benefit · Retinal
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.3–2%
Anti-blemish
Side benefit · Retinal, Centella asiatica leaf extract + 1 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinal. This ingredient is used for treating acne and can have a noticeable effect.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.3–2%
Centella asiatica leaf extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.~1–1.45%
Rosmarinus officinalis leaf extractUnder-dosedCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.1–0.4%

Can it cause trouble?

Irritancy
2 strong irritants: Retinal, Rosmarinus officinalis leaf extract
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~1.3–2%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.1–0.4%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~2.1–3.1%est.
Centella asiatica leaf extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.Medium~1–1.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.8%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.3%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.05%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.9–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Propanediol~3.4–5.2%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Dimethicone~2.7–4.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Simmondsia chinensis seed oil~2.1–3.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Hydroxyapatite~1.7–2.6%
Formula
Irritation risk
Low
More about Hydroxyapatite
Retinal~1.3–2%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingAnti-blemish

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal
Ectoin~1.2–1.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Centella asiatica leaf extract~1–1.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces irritationReduces rednessAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.

More about Centella asiatica leaf extract
Cyanocobalamin~0.6–1.4%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Oryza sativa bran extract~0.5–1.1%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Helianthus annuus extract~0.4–1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus extract
Tocopherol~0.35–0.85%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Boron nitride~0.35–0.85%
Formula
Irritation risk
Low

Helps to absord oil and evenly disperse other ingredients (for example, pigment) in product formulation

More about Boron nitride
Coco-caprylate/caprate~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate
Caprylic/capric triglyceride~0.35–0.8%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cetyl alcohol~0.35–0.8%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearyl alcohol~0.3–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Glyceryl stearate~0.2–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Glyceryl stearate citrate~0.2–0.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
C9-12 alkane~0.15–0.6%
Formula
Irritation risk
Low

Helps dissolve other ingredients in a formulation

More about C9-12 alkane
Castor oil/ipdi copolymer~0.15–0.6%
Formula
Irritation risk
Low

Helps improve the product texture

More about Castor oil/ipdi copolymer
Ammonium acryloyldimethyltaurate/vp copolymer~0.15–0.5%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Dilinoleic acid/butanediol copolymer~0.15–0.5%
Formula
Carbomer~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Rosmarinus officinalis leaf extract~0.1–0.4%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Sclerotium gum~0.1–0.4%
Formula
Irritation risk
Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum
Xanthan gum~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Phenoxyethanol~0.05–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Dipropylene glycol~0.05–0.25%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Caprylyl glycol~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium phytate~0.05–0.2%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Sodium hydroxide~0.05–0.15%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Citric acid~0.01–0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Glycerin, Propanediol, Dimethicone, Simmondsia chinensis seed oil, Hydroxyapatite, Retinal, Ectoin, Centella asiatica leaf extract, Cyanocobalamin, Oryza sativa bran extract, Helianthus annuus extract, Tocopherol, Boron nitride, Coco-caprylate/caprate, Caprylic/capric triglyceride, Cetyl alcohol, Stearyl alcohol, Glyceryl stearate, Glyceryl stearate citrate, C9-12 alkane, Castor oil/ipdi copolymer, Ammonium acryloyldimethyltaurate/vp copolymer, Dilinoleic acid/butanediol copolymer, Carbomer, Rosmarinus officinalis leaf extract, Sclerotium gum, Xanthan gum, Phenoxyethanol, Dipropylene glycol, Caprylyl glycol, Sodium phytate, Sodium hydroxide, Citric acid

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Amazon USPrice as of 11/14 09:11 GMT
$28.99
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Prequel
$29.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
PrequelRETINAL RENEWYOUR PRODUCTDieux SkinFirm Revival HydroRetinal Firming SerumPaula's choicePRO Retinaldehyde Dual-Retinoid TreatmentUrsa MajorLunar Bloom Retinal Serum
Match—86%84%81%
Price$28.99—$68.00+$39.01$76.00+$47.01
Shared key ingredients—6 of 106 of 104 of 10
Key difference—PanthenolIsopropyl MyristateGardenia Jasminoides Meristem Cell Culture
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

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