PharmaClinix Lightenex Gold Cream

PharmaClinix Lightenex Gold Cream

Efficacy100/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Evens skin tone
Retinal, Alpha-arbutin + 8 more
Strong evidence
What the product description says
“Brighten areas of resistant hyperpigmentation with PharmaClinix Lightenex Gold 30ml, now available at Face the Future Advanced Skin Clinic and Online Shop.”
Source: Face the future

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal.

In addition, this product contains acetyl glucosamine, alpha-arbutin, lactic acid, niacinamide, salicylic acid. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: arbutin, ferulic acid, glycyrrhiza glabra root extract, magnesium ascorbyl phosphate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.5–2.3%
Alpha-arbutinKey activeEffect: HighMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin~23–35%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.95–1.4%
Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~3.7–5.5%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.55–1.3%
ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~5.8–8.7%
Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.3–0.7%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~1.4–2.1%
Magnesium ascorbyl phosphateEffect: LowA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~4.9–7.3%
Salicylic acidEffect: LowUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.3–1.9%
Moisturizing
Not advertised by the brand · Acetyl glucosamine, Niacinamide + 3 more
Strong evidence

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": hyaluronic acid, lactic acid.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, niacinamide

Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.55–1.3%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.45–1.05%
Lactic acidKey active· HumectantEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~3.7–5.5%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.95–1.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.75%
Anti-aging
Not advertised by the brand · Retinal, Acetyl glucosamine + 6 more
Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, acetyl glucosamine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ferulic acid, lactic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.55–1.3%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.95–1.4%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.5–2.3%
Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.3–0.7%
Lactic acidKey activeEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~3.7–5.5%
Magnesium ascorbyl phosphateEffect: LowA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~4.9–7.3%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.45–1.05%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.75%
Exfoliation
Not advertised by the brand · Salicylic acid, Lactic acid + 1 more
Strong evidence

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: lactic acid, salicylic acid.

Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.3–1.9%
Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~3.7–5.5%
Acetyl glucosamineKey activeEffect: MediumAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.55–1.3%
Anti-oxidation
Not advertised by the brand · Ferulic acid, Arbutin + 3 more
Strong evidence

This product contains antioxidants (ferulic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - arbutin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Ferulic acidKey activeEffect: HighA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.3–0.7%
ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~5.8–8.7%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~1.4–2.1%
Magnesium ascorbyl phosphateEffect: LowA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~4.9–7.3%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.75%
Anti-blemish
Not advertised by the brand · Niacinamide, Retinal + 2 more
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, retinal, salicylic acid. These ingredients is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.95–1.4%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~1.5–2.3%
Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.3–1.9%
Octadecenedioic acidEffect: LowHelps oil and water mix together. Might help suppress growth of acne-triggering bacteria in skin~2.8–4.1%

Can it cause trouble?

Irritancy
1 strong irritant: Retinal
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~1.3–1.9%est.
RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~1.5–2.3%est.
Alpha-arbutinMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutinMedium~23–35%est.
ArbutinBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutinMedium~5.8–8.7%est.
Magnesium ascorbyl phosphateA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very highMedium~4.9–7.3%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~3.7–5.5%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~1.4–2.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Alpha-arbutin~23–35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin

More about Alpha-arbutin
Arbutin~5.8–8.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin

More about Arbutin
Magnesium ascorbyl phosphate~4.9–7.3%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-agingAnti-oxidation

A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high

More about Magnesium ascorbyl phosphate
Lactic acid~3.7–5.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Octadecenedioic acid~2.8–4.1%
Formula
Irritation risk
Low
Works for
CleansingAnti-blemish

Helps oil and water mix together. Might help suppress growth of acne-triggering bacteria in skin

More about Octadecenedioic acid
Salicylic acid~1.3–1.9%
Hero · Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishExfoliationAnti-inflammatoryAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Retinal~1.5–2.3%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-agingEvens skin tone

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal
Glycyrrhiza glabra root extract~1.4–2.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-oxidationEvens skin toneReduces rednessAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Niacinamide~0.95–1.4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Acetyl glucosamine~0.55–1.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Hyaluronic acid~0.45–1.05%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Ferulic acid~0.3–0.7%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-agingEvens skin toneAnti-inflammatory

A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%

More about Ferulic acid
Tocopherol~0.2–0.75%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Bioflavonoids~0.2–0.7%
Formula
Irritation risk
Low
More about Bioflavonoids
Ingredient list view

Alpha-arbutin, Arbutin, Magnesium ascorbyl phosphate, Lactic acid, Octadecenedioic acid, Salicylic acid, Retinal, Glycyrrhiza glabra root extract, Niacinamide, Acetyl glucosamine, Hyaluronic acid, Ferulic acid, Tocopherol, Bioflavonoids

Compare prices

Retailers ranked by price — lowest first.

Amazon UKPrice as of 10/17/2026 21:17 GMT
≈ $93.51
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Face the future
≈ $102.92
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
PharmaClinixLightenex Gold CreamYOUR PRODUCTHELPAnti Dark Spot SerumUrban Skin RxHydraFirm + Brightening Serum
Match—58%51%
Price$93.56$7.26−$86.30$23.00−$70.56
Shared key ingredients—5 of 104 of 10
Key difference—Azelaic AcidAcetyl Hexapeptide-8
Irritancy Medium Medium Low
Drying alcohol———
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Product summary

Judging from the ingredient list, "PharmaClinix - Lightenex Gold Cream" works well for improving skin hydration

Ingredient callouts

  • this moisturizer contains an effective form of retinoids (vitamin A): retinal 1.40% - 2.00%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
  • There is also Azelaic Acid (2.10% - 3.10%). In this formulation. It is a helpful active to strengthen the skin barrier, reduce hyperpigmentation and help with blemishes. Please note that Azelaic Acid is most effective against acne in concentrations between 10% and 20%.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 56.85£ up to 74.99£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 25 studies and safety reviews.

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PharmaClinix Lightenex Gold Cream
PharmaClinixLightenex Gold Cream

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