Peter Thomas Roth VITAL-E MICROBIOME AGE DEFENSE CREAM - Day care

Peter Thomas Roth VITAL-E MICROBIOME AGE DEFENSE CREAM - Day care

Efficacy87/100IrritancyLow
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Works for

2 of 2 advertised claims delivered

Moisturizing
Ceramide np, Dimethicone + 13 more
Strong evidence
What the product description says
“Moisturizing cream moisturizes the skin, protects it from blue light, and helps smooth out fine lines and wrinkles.”
Source: N/A

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, mannitol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, paraffin.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.7–5.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–6.5%
InulinKey activeEffect: HighHelps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking~0.1–0.45%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.1–0.4%
Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.1–0.45%
Undaria pinnatifida extractKey activeEffect: HighA seaweed extract that helps attract water to the upper layer of the skin and might have an anti-oxidant effect~0.15–0.6%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.75%
Paraffin· OcclusiveEffect: LowPrevents water loss from the skin surface and thickens the product consistency~0.05–0.15%
Caprylyl methiconeEffect: LowA type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin~2–3%
CeresinEffect: Low~1.4–2%
Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.15–0.55%
Lauryl peg-9 polydimethylsiloxyethyl dimethiconeEffect: LowA type of silicone that helps to soften upper layer of the skin and create a nice product texture~1–1.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.7–2.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.85%
Anti-aging
Tocopherol
Moderate evidence
What the product description says
“Anti-contamination ingredients, prebiotics and probiotics improve the appearance of skin with signs of aging due to environmental factors and restore its vitality.”
Source: N/A

This product contains dimethylmethoxy chromanol. This ingredient help neutralize free radicals in skin. By doing so, they might be able to prevent early signs of aging (like fine lines and wrinkles), at least to some extent. These ingredients will not be able to "reverse" signs of aging.

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.85%
Anti-oxidation
Not advertised by the brand · Dimethylmethoxy chromanol, Eclipta prostrata extract + 2 more
Strong evidence

This product contains antioxidants (dimethylmethoxy chromanol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Dimethylmethoxy chromanolKey activeEffect: HighCan help neutralize free radicals in skin~0.4–0.95%
Eclipta prostrata extractEffect: LowA plant extract that might help neutralize free radicals in skin. It can be irritating~0.15–0.55%
Undaria pinnatifida extractEffect: LowA seaweed extract that helps attract water to the upper layer of the skin and might have an anti-oxidant effect~0.15–0.6%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.85%

Can it cause trouble?

Irritancy
8 flagged ingredients
Low risk
We flag 8 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Eclipta prostrata extractA plant extract that might help neutralize free radicals in skin. It can be irritatingHigh~0.15–0.55%est.
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.15–0.55%est.
Dimethicone/peg-10/15 crosspolymerHelps oil and water mix togetherMedium~1.3–1.9%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.15–0.55%est.
Potassium sorbateA preservativeMedium~0.1–0.45%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.1–0.3%est.
Hydroxypropyl methylcelluloseUsed to create a thicker product consistency and stabilize the formulationMedium~0.1–0.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.3%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–6.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~3.7–5.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Methyl trimethicone~2.7–4.1%
Formula
Irritation risk
Low

A type of silicone that helps create a silky product finish and dissolve other ingredients

More about Methyl trimethicone
Caprylyl methicone~2–3%
Formula
Irritation risk
Low
Works for
Moisturizing

A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin

More about Caprylyl methicone
Butylene glycol~1.7–2.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Ceresin~1.4–2%
Formula
Irritation risk
Low
Works for
Moisturizing
More about Ceresin
Dimethicone/peg-10/15 crosspolymer~1.3–1.9%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Dimethicone/peg-10/15 crosspolymer
Lauryl peg-9 polydimethylsiloxyethyl dimethicone~1–1.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

A type of silicone that helps to soften upper layer of the skin and create a nice product texture

More about Lauryl peg-9 polydimethylsiloxyethyl dimethicone
Astrocaryum tucuma seed butter~0.85–1.25%
Formula
Microcrystalline wax~0.55–1.25%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Microcrystalline wax
Dimethylmethoxy chromanol~0.4–0.95%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin

More about Dimethylmethoxy chromanol
Tocopherol~0.35–0.85%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Bacillus~0.3–0.75%
Formula
Irritation risk
Low
More about Bacillus
Yeast beta-glucan~0.3–0.7%
Formula
Acetyl heptapeptide-4~0.2–0.8%
Formula
Silybum marianum seed extract~0.2–0.75%
Formula
Hedychium coronarium root extract~0.15–0.65%
Formula
Ceramide np~0.2–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Undaria pinnatifida extract~0.15–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A seaweed extract that helps attract water to the upper layer of the skin and might have an anti-oxidant effect

More about Undaria pinnatifida extract
Eclipta prostrata extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-inflammatory

A plant extract that might help neutralize free radicals in skin. It can be irritating

More about Eclipta prostrata extract
Melia azadirachta leaf extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Moringa oleifera seed oil~0.15–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Inulin~0.1–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-blemish

Helps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking

More about Inulin
Sodium pca~0.1–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Phenoxyethanol~0.1–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Potassium sorbate~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Mannitol~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Cellulose~0.1–0.5%
Formula
Irritation risk
Low
Works for
Mattifying

Can be used to help absorb oil as well as add volume and imporve texture of products.

More about Cellulose
Dipropylene glycol dibenzoate~0.1–0.45%
Formula
Sodium citrate~0.1–0.3%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Hydroxypropyl methylcellulose~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Hydroxypropyl methylcellulose
Caprylyl glycol~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Paraffin~0.05–0.15%
Formula
Irritation risk
Low
Works for
Moisturizing

Prevents water loss from the skin surface and thickens the product consistency

More about Paraffin
Mica~0.05–0.15%
Formula
Irritation risk
Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica
Ingredient list view

Water, Glycerin, Dimethicone, Methyl trimethicone, Caprylyl methicone, Butylene glycol, Ceresin, Dimethicone/peg-10/15 crosspolymer, Lauryl peg-9 polydimethylsiloxyethyl dimethicone, Astrocaryum tucuma seed butter, Microcrystalline wax, Dimethylmethoxy chromanol, Tocopherol, Bacillus, Yeast beta-glucan, Acetyl heptapeptide-4, Silybum marianum seed extract, Hedychium coronarium root extract, Ceramide np, Undaria pinnatifida extract, Eclipta prostrata extract, Melia azadirachta leaf extract, Moringa oleifera seed oil, Inulin, Sodium pca, Phenoxyethanol, Potassium sorbate, Mannitol, Cellulose, Dipropylene glycol dibenzoate, Sodium citrate, Hydroxypropyl methylcellulose, Caprylyl glycol, Paraffin, Mica

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Peter Thomas RothVITAL-E MICROBIOME AGE DEFENSE CREAM - Day careYOUR PRODUCTAESTURAATOBARRIER365 Cooling Hydro Soothing Water Cream Moisturizer with Ceramides & Hyaluronic Acid for Moisture Barrier RepairQVDermcare Eczema Daily Cream With CeramidesEucerinAtoControl Face Care Cream
Match—55%54%53%
Price—$32.00—$18.46
Shared key ingredients—4 of 104 of 104 of 10
Key difference—BetaineNiacinamidePhytosphingosine
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

Based on the ingredients included, "Peter Thomas Roth - VITAL-E MICROBIOME AGE DEFENSE CREAM - Day care" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Peter Thomas Roth - VITAL-E MICROBIOME AGE DEFENSE CREAM - Day care ticks this box. Glycerin, mannitol, sodium pca, butylene glycol and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, dimethicone, caprylyl glycol, moringa oleifera seed oil and paraffin) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • As a plus, this moisturizer also contains ceramides (ceramide np 0.20% - 0.75%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Peter Thomas Roth VITAL-E MICROBIOME AGE DEFENSE CREAM - Day care
Peter Thomas RothVITAL-E MICROBIOME AGE DEFENSE CREAM - Day care

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