Peter Thomas Roth Peptide 21 Lift & Firm Moisturizer
Something wrong? Edit here- Anti-aging
- Moisturizing
- Anti-oxidation
- +1 more
- hexapeptide-11
- acetyl hexapeptide-1
- acetyl tetrapeptide-11
- +33 more
FULFILLED

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Formula review
Promise
What does the product description say?WIMJ summary
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl tetrapeptide-11, acetyl tetrapeptide-2, acetyl tetrapeptide-9, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-11, palmitoyl hexapeptide-19, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, trifluoroacetyl tripeptide-2, tripeptide-1, tripeptide-10 citrulline.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
MEDIUM
| |||
MEDIUM
|
Promise
What does the product description say?WIMJ summary
Effective ingredients missing or their concentration is too low
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
LOW
|
Promise
What does the product description say?WIMJ summary
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
dextran, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl tetrapeptide-11, acetyl tetrapeptide-2, acetyl tetrapeptide-9, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-11, palmitoyl hexapeptide-12, palmitoyl hexapeptide-19, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, trifluoroacetyl tripeptide-2, tripeptide-1, tripeptide-10 citrulline
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
HIGH | |||
HIGH |
WIMJ summary
This product contains antioxidants (cereus grandiflorus flower extract, squalene) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
MEDIUM
| |||
MEDIUM
| |||
LOW
|
Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
simmondsia chinensis seed oil | ||
sorbic acid | ||
cereus grandiflorus flower extract |
Ingredients by volume
Ingredient | Estimated concentration |
---|---|
Plain old water
| 45% - 55% |
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
| 4.7% - 5.7% |
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
| 4.2% - 5.1% |
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Questions
Skincare resources
Scientific Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Glycerin Ethoxylates as Used in Cosmetics
- Squalene and its potential clinical uses
- Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology
- Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxides
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Wheat in skin care
- Extracts from Glycine max (soybean) induce elastin synthesis and inhibit elastase activity
- Dermatological and cosmeceutical benefits of Glycine max (soybean) and its active components
- Safety Assessment of Soy Peptides as Used in Cosmetics
- Final Report on the Safety Assessment of Acrylates Copolymer and 33 Related Cosmetic Ingredients