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Perricone MD Neuropeptide Smoothing Facial Conformer
Perricone MD

Perricone MD Neuropeptide Smoothing Facial Conformer

Efficacy66/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 + 4 more
Works well
What the product description says
“This unique combination of concentrated, patented sciences tackles the look of advanced photo-damage and discoloration, rough, dull texture, fine lines and wrinkles.”
Source: Perricone MD

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.25–0.45%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.25–0.5%
Tetrahexyldecyl ascorbateUnder-dosedBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.5–0.7%
Moisturizing
Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 + 19 more
Works well
What the product description says
“They work alongside the skin’s natural barrier to maintain normal hydration while improving the look of your complexion.”
Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, c12-15 alkyl benzoate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.6%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~5.3–6.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.1–2.5%
TyrosineKey activeEffect: High~1.6–2%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.1–1.3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.65–0.95%
Hydrolyzed oat proteinKey activeEffect: MediumHelps attract water to the upper layer of the skin~0.3–0.55%
Magnesium aspartateKey activeEffect: MediumMight be helpful in restoring skin barrier function and calm down inflammation in skin~0.25–0.5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.2–3.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–1.8%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.7–1.05%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.25–0.4%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.25–0.45%
Glyceryl polymethacrylate· Humectant, EmollientEffect: LowUsed to create a nice product texture~0.25–0.45%
Simmondsia chinensis seed oilUnder-dosedSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.55–0.85%
Zinc gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.25–0.5%
Copper gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.25–0.45%
Evens skin tone
Tetrahexyldecyl ascorbate ~0.5–0.7%
Under-dosed
What the product description says
“This unique combination of concentrated, patented sciences tackles the look of advanced photo-damage and discoloration, rough, dull texture, fine lines and wrinkles.”
Source: Perricone MD

Effective ingredients missing or their concentration is too low

Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.25–0.45%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.25–0.5%
Tetrahexyldecyl ascorbateUnder-dosedBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.5–0.7%

Can it cause trouble?

Irritancy
2 strong irritants: Imidazolidinyl urea, Parfum
Medium risk
We flagged 18 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.25–0.4%est.
Imidazolidinyl ureaA preservative. Is more irritating than many other preservatives availableHigh~0.15–0.3%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.15%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.2%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~2.4–2.9%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.7–1.05%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.55–0.85%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.5–0.7%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.45–0.65%est.
Zinc gluconateTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skinMedium~0.25–0.5%est.
Copper gluconateTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missingMedium~0.25–0.45%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
BhtA preservativeMedium~0.25–0.45%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
Peg-10 phytosterolHelps oil and water mix togetherMedium~0.25–0.45%est.
Sorbic acidA preservativeMedium~0.15–0.3%est.
Potassium sorbateA preservativeMedium~0.15–0.3%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.7–1.05%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
C12-15 alkyl benzoate~5.3–6.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Dimethyl mea~4.5–5.5%
Formula
Irritation risk
Low
More about Dimethyl mea
Butylene glycol~3.2–3.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Citric acid~2.4–2.9%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Glycerin~2.1–2.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Tyrosine~1.6–2%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Glyceryl stearate~1.5–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~1.3–1.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Cetyl alcohol~1.1–1.3%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Isopropyl palmitate~0.7–1.05%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Dimethicone~0.65–0.95%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Simmondsia chinensis seed oil~0.55–0.85%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Tetrahexyldecyl ascorbate~0.5–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin toneAnti-aging

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Phosphatidylcholine~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Palmitoyl tripeptide-1~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tetrapeptide-7~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl hexapeptide-12~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingMoisturizing

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Hydrolyzed oat protein~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Hydrolyzed oat protein
Ceramide ng~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Zinc gluconate~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-blemishAnti-oxidationEvens skin toneAnti-agingAnti-inflammatoryExfoliation

Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin

More about Zinc gluconate
Magnesium aspartate~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

Might be helpful in restoring skin barrier function and calm down inflammation in skin

More about Magnesium aspartate
Copper gluconate~0.25–0.45%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-blemishExfoliationAnti-oxidationAnti-agingEvens skin tone

Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing

More about Copper gluconate
Rutin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Anti-oxidation

An antioxidant that might help neutralize free radicals in skin

More about Rutin
Sodium carboxymethyl beta-glucan~0.65–0.95%
Formula
Irritation risk
Low

Helps thicken the product formulation and create a gel-like texture

More about Sodium carboxymethyl beta-glucan
Phaseolus lunatus seed extract~0.3–0.55%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Bean seed extract. It might have some anti-oxidant properties

More about Phaseolus lunatus seed extract
Carbomer~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Bht~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Triethanolamine~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Propylene glycol~0.25–0.4%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Ammonium acryloyldimethyltaurate/vp copolymer~0.2–0.4%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Peg-10 phytosterol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-10 phytosterol
Polysorbate 20~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Cetyl hydroxyethylcellulose~0.25–0.4%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize formulations

More about Cetyl hydroxyethylcellulose
Glyceryl polymethacrylate~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture

More about Glyceryl polymethacrylate
Tribehenin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Phenoxyethanol~0.2–0.35%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sorbic acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Sodium benzoate~0.15–0.25%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Imidazolidinyl urea~0.15–0.3%
Irritant · high
Irritation risk
High

A preservative. Is more irritating than many other preservatives available

More about Imidazolidinyl urea
Parfum~0.1–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Benzyl alcohol~0.1–0.2%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Ingredient list view

Water, C12-15 alkyl benzoate, Dimethyl mea, Butylene glycol, Citric acid, Glycerin, Tyrosine, Glyceryl stearate, Peg-100 stearate, Cetyl alcohol, Isopropyl palmitate, Dimethicone, Simmondsia chinensis seed oil, Tetrahexyldecyl ascorbate, Phosphatidylcholine, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Palmitoyl hexapeptide-12, Hydrolyzed oat protein, Ceramide ng, Zinc gluconate, Magnesium aspartate, Copper gluconate, Rutin, Sodium carboxymethyl beta-glucan, Phaseolus lunatus seed extract, Carbomer, Disodium edta, Bht, Triethanolamine, Caprylyl glycol, Propylene glycol, Ammonium acryloyldimethyltaurate/vp copolymer, Peg-10 phytosterol, Polysorbate 20, Cetyl hydroxyethylcellulose, Glyceryl polymethacrylate, Tribehenin, Phenoxyethanol, Sorbic acid, Sodium benzoate, Potassium sorbate, Imidazolidinyl urea, Parfum, Benzyl alcohol

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Perricone MD
$495.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDNeuropeptide Smoothing Facial ConformerYOUR PRODUCTEveline CosmeticsSerum Shot Multi Peptides & Collagen Serum RejuvenationRaz SkincareHh - Hyaluronic Acid SerumCliniqueSmart Wrinkle Correcting Serum All Skin Types
Match—49%49%46%
Price$495.00—$80.00−$415.00$80.00−$415.00
Shared key ingredients—6 of 125 of 125 of 12
Key difference—N-Prolyl Palmitoyl Tripeptide-56 AcetateSodium HyaluronateHydroxypinacolone Retinoate
Irritancy Medium Medium Low Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Final Report on the Safety Assessment of Isopropyl Isostearatejournals.sagepub.com
  3. 3
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  4. 4
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  5. 5
    Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamagencbi.nlm.nih.gov
  6. 6
    Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacysciencedirect.com
Perricone MD Neuropeptide Smoothing Facial Conformer
Perricone MDNeuropeptide Smoothing Facial Conformer
Buy at Perricone MD$495.00Amazon

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Buy at Perricone MD$495.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.