Perricone MD Neuropeptide Firming Moisturiser
Works for
MoisturizingAcetyl hexapeptide-8, Cetearyl alcohol + 6 moreWorks well
“Deeply nourishes and hydrates”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
sodium hyaluronate, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8
Anti-agingAcetyl hexapeptide-8May help
“Twenty years of research have yielded our most advanced firming moisturizer. This luxurious, ultra-powerful formula provides essential, all-day hydration and helps dramatically improve the feel of thin, sagging skin over time for a noticeably younger-looking complexion.”
This product contains acetyl hexapeptide-8. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Evens skin toneTaurineNot delivered
“The formula also helps to reduce the appearance of enlarged pores, discolouration and wrinkles, leading to a brighter, softer and younger-looking complexion.”
Effective ingredients missing or their concentration is too low
Can it cause trouble?
Irritancy6 strong irritants: Parfum, Citral + 4 more — patch-test recommendedHigh risk
Comedogenic3 ingredients rated 2 or more on the 0–5 pore-clogging scale3 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Isopropyl palmitate~5.7–8.6%
- Irritation risk
- Medium
- Comedogenicity
- 3/5
Helps soften the upper layer of the skin and create a thicker product consistency
More about Isopropyl palmitateCetearyl alcohol~3.8–5.6%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholTaurine~3.1–4.7%
- Irritation risk
- Medium
Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness
More about TaurineTyrosine~2.3–3.5%
Glyceryl stearate~2–3%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearatePeg-100 stearate~1.7–2.5%
- Irritation risk
- Low
Helps oil and water mix togehter and creates a nice product texture
More about Peg-100 stearateCeteareth-20~1.4–2.1%
- Irritation risk
- Medium
- Comedogenicity
- 2/5
Helps oil and water mix together. Has some emollient properties
More about Ceteareth-20Phosphatidylcholine~1.1–1.6%
- Irritation risk
- Medium
Used to enhance the delivery of other ingredients
More about PhosphatidylcholineDimethyl mea~0.85–1.25%
- Irritation risk
- Low
Acetyl hexapeptide-8~0.5–1.15%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Sodium hyaluronate~0.4–0.95%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateDisodium edta~0.35–0.85%
Dimethicone~0.4–0.9%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeCaprylyl glycol~0.35–0.75%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolPhenoxyethanol~0.15–0.6%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolSorbic acid~0.15–0.55%
Potassium sorbate~0.15–0.5%
Parfum~0.1–0.4%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumCitral~0.1–0.35%
Citronellol~0.1–0.35%
Geraniol~0.05–0.25%
Hydroxycitronellal~0.05–0.2%
- Irritation risk
- High
A fragrance. A likely allergen and can be irritating
More about HydroxycitronellalLinalool~0.05–0.15%
Ingredient list view
Water, Isopropyl palmitate, Cetearyl alcohol, Taurine, Tyrosine, Glyceryl stearate, Peg-100 stearate, Ceteareth-20, Phosphatidylcholine, Dimethyl mea, Acetyl hexapeptide-8, Sodium hyaluronate, Disodium edta, Dimethicone, Caprylyl glycol, Phenoxyethanol, Sorbic acid, Potassium sorbate, Parfum, Citral, Citronellol, Geraniol, Hydroxycitronellal, Linalool
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDNeuropeptide Firming MoisturiserYOUR PRODUCT | EvercellDeep Wrinkle Solution Cream Syringe Type | NeolastinRejuvenate & Hydrate Moisturizing Cream | CliniqueSmart Clinical Repair Wrinkle Correcting Rich Cream | |
|---|---|---|---|---|
| Match | — | 66% | 64% | 64% |
| Price | $139.00 | $14.10−$124.90 | — | $63.49−$75.51 |
| Shared key ingredients | — | 4 of 4 | 3 of 4 | 3 of 4 |
| Key difference | — | Copper Tripeptide-1 | Alanine | Acetyl Octapeptide-3 |
| Irritancy | High | Medium | Low | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: JMsolution Honey Luminous Royal Propolis CreamToo Faced Hangover Mini Pillow Cream
Product summary
Based on the ingredients included, "Perricone MD - Neuropeptide Firming Moisturiser" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Perricone MD - Neuropeptide Firming Moisturiser ticks this box. Humectants in this product (acetyl hexapeptide-8, sodium hyaluronate and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Dimethicone, cetearyl alcohol, caprylyl glycol, glyceryl stearate and isopropyl palmitate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- This moistruizer also contains peptides (acetyl hexapeptide-8 0.50% - 1.15%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails from 260.60$ up to 290.00$ in the United States, for 89.70CA$ in Canada and from 118.00£ up to 236.00£ in the United Kingdom.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 7 studies and safety reviews.
- 1Final Report on the Safety Assessment of Isopropyl Isostearatejournals.sagepub.com
- 2Cosmeceuttical Critigue: Taurinemdedge.com
- 3Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 4
- 5
- 6Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
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