Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Anti-oxidation
Doesn't work for:
based on ingredients and %- Exfoliation
- Evens skin tone
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"Perricone MD - Neuropeptide Facial Conformer" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Perricone MD - Neuropeptide Facial Conformer ticks this box. Humectants in this product (glycerin, butylene glycol, caprylyl glycol, peg-8 and glyceryl polymethacrylate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide 2, palmitoyl tetrapeptide-7, dimethicone, c12-15 alkyl benzoate and cetyl alcohol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- As a plus, this moisturizer also contains ceramides (ceramide 2 0.25% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (palmitoyl tetrapeptide-7 0.25% - 0.50% and palmitoyl oligopeptide 0.30% - 0.60%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails from 81.25$ up to 495.00$ in the United States and for 651.93A$ in Australia.
For a detailed price comparison: click here.
Anti-oxidation
This product contains antioxidants (tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
An antioxidant that might help neutralize free radicals in skin
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Moisturizing
What does the product description say?
Improves the skin's resilience, tone and texture Decreases appearance of fine lines and wrinkles Decreases appearance of scars, tiny veins and capillaries Maximizes regeneration and hydration of the skin Combats the crepey appearance of aging skin Increases circulation, resulting in a radiant glow Clinical Results.
Source: Skinstore
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, butylene glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, c12-15 alkyl benzoate.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, palmitoyl oligopeptide, palmitoyl tetrapeptide-7
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Might be helpful in restoring skin barrier function and calm down inflammation in skin
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
Helps soften the upper layer of the skin
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
Helps preserve products and creates a nice product texture
Used to create a nice product consistency
Used to create a thicker product consistency and soften the upper layer of the skin
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps soften the upper layer of the skin and create a thicker product consistency
Used to create a nice product texture
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-aging
What does the product description say?
It has been proven that Neuropeptides play many important roles in maintaining youthful, beautiful skin.
Source: Skinstore
This product contains palmitoyl oligopeptide, palmitoyl tetrapeptide-7, tocotrienols. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Evens skin tone
What does the product description say?
Improves the skin's resilience, tone and texture Decreases appearance of fine lines and wrinkles Decreases appearance of scars, tiny veins and capillaries Maximizes regeneration and hydration of the skin Combats the crepey appearance of aging skin Increases circulation, resulting in a radiant glow Clinical Results.
Source: Skinstore
Effective ingredients missing or their concentration is too low
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Exfoliation
What does the product description say?
This highly advanced proprietary Neuropeptide treatment activates surface renewal to reveal visibly younger looking skin.
Source: Bluemercury
This product does not contain effective exfoliating ingredients. It might be able to deliver physical exfoliation, that is scrub off some of the dead cells on the surface of the skin. We do not recommend physical exfoliation, because it is not uniform (some bits of skin can get exfoliated too much while others not at all). It can also traumatize the skin and aggrevate acne and other skin conditions.
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging | |
| Exfoliation | |
| Evens skin tone |
Total Promises Fulfilled score: 43/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Perricone MD Neuropeptide Facial Conformer | Current | $81.25 | |
 M-61 Hydraboost Moisturizer | 53% | $78.00 |
Key Actives
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Might be helpful in restoring skin barrier function and calm down inflammation in skin
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
Can work as an exfoliant but is typically used to adjust the product pH
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Helps soften the upper layer of the skin and create a thicker product consistency
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Used to adjust pH of the product and can help improve the product's smell
Helps preserve products and creates a nice product texture
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Comedogenic ingredients
Helps soften the upper layer of the skin and create a thicker product consistency
All ingredients
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Can work as an exfoliant but is typically used to adjust the product pH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Used to create a thicker product consistency and soften the upper layer of the skin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Helps soften the upper layer of the skin and create a thicker product consistency
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A preservative. It helps prevent bacterial growth in cosmetic products
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Used to adjust pH of the product and can help improve the product's smell
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Helps preserve products and creates a nice product texture
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Helps thicken the product formulation and create a gel-like texture
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
Might be helpful in restoring skin barrier function and calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Used to create a thicker product consistency and stabilize formulations
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An aromatic blend of unspecified and possibly irritating ingredients
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
Ingredient list view
Water, C12-15 alkyl benzoate, Butylene glycol, Dimethyl mea, Glyceryl polymethacrylate, Citric acid, Glycerin, Glyceryl stearate, Peg-100 stearate, Avena sativa protein extract, Cetyl alcohol, Tribehenin, Simmondsia chinensis seed oil, Isopropyl palmitate, Dimethicone, Peg-8, Phenoxyethanol, Phosphatidylcholine, Tetrahexyldecyl ascorbate, Triethanolamine, Tyrosine, Carbomer, Caprylyl glycol, Ceramide 2, Peg-10 rapeseed sterol, Disodium edta, Bht, Sodium carboxymethyl beta-glucan, Ammonium acryloyldimethyltaurate/vp copolymer, Magnesium aspartate, Zinc gluconate, Sorbic acid, Elaeis guineensis oil, Tocotrienols, Cetyl hydroxyethylcellulose, Polysorbate 20, Rutin, Tocopherol, Copper gluconate, Ascorbyl palmitate, Palmitoyl oligopeptide, Palmitoyl tetrapeptide-7, Parfum, Vegetable oil, Rosa damascena extract
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