Perricone MD Hypoallergenic Nourishing Moisturizer

Perricone MD Hypoallergenic Nourishing Moisturizer

Efficacy100/100IrritancyLow
Edit

Works for

1 of 1 advertised claim delivered

Moisturizing
24 ingredients credited for this claim
Strong support
What the product description says
“Hypoallergenic Nourishing Moisturizer”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, palmitoyl oligopeptide, panthenol

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.1–0.2%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1–1.2%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.7–8.2%
Ceramide 2Hero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.4–3%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~0.35–0.65%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.1–3.8%
Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.4–0.65%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.6–0.95%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~1.2–1.4%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.7–2%
Stearyl glycyrrhetinateKey activeEffect: MediumA fatty acid derived from licorice. Works as an emollient and can help calm down inflammation~0.2–0.4%
Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.25–0.4%
Acacia decurrens/jojoba/sunflower seed wax polyglyceryl-3 estersKey active· EmollientEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~1.9–2.4%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.45%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–1.8%
Olea europaea fruit extract· EmollientEffect: LowAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.2–0.35%
Peg-8 dimethiconeEffect: LowA type of silicone that can help create nice product texture and soften the upper layer of the skin~4.4–5.4%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.35–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.5%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.4%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

TocotrienolsKey activeEffect: HighA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.15–0.3%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1–1.2%
Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.2–0.35%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%
Anti-aging
Not advertised by the brand · 5 ingredients credited for this claim
Moderate support

This product contains palmitoyl oligopeptide, tocotrienols. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
TocotrienolsKey activeEffect: MediumA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.15–0.3%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1–1.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.4%
Evens skin tone
Not advertised by the brand · 1 ingredient credited for this claim
Moderate support

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: stearyl glycyrrhetinate.

Stearyl glycyrrhetinateKey activeEffect: MediumA fatty acid derived from licorice. Works as an emollient and can help calm down inflammation~0.2–0.4%

Can it cause trouble?

Irritancy
12 flagged ingredients
Low risk
We flag 12 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.35–0.65%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.7–8.2%est.
Acacia decurrens/jojoba/sunflower seed wax polyglyceryl-3 estersHelps soften the upper layer of the skin and create a nice product textureMedium~1.9–2.4%est.
EthoxydiglycolHelps to improve the product consistencyMedium~0.65–0.95%est.
Peg-75 stearateHelps water and oil mix togetherMedium~0.45–0.7%est.
Ceteth-20Helps water and oil mix togetherMedium~0.5–0.7%est.
Steareth-20Helps oil and water mix togetherMedium~0.4–0.65%est.
Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.2–0.35%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.25–0.4%est.
Stearyl glycyrrhetinateA fatty acid derived from licorice. Works as an emollient and can help calm down inflammationMedium~0.2–0.4%est.
Dehydroacetic acidA preservativeMedium~0.2–0.4%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.1–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1–1.2%est.
Edit
Cheaper Alternatives
Similar formulations, better price
No cheaper similar product found.

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Write a review · ~30s

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.7–8.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Peg-8 dimethicone~4.4–5.4%
Formula
Irritation risk
Low
Works for
Moisturizing

A type of silicone that can help create nice product texture and soften the upper layer of the skin

More about Peg-8 dimethicone
Glycerin~3.1–3.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~2.4–3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Acacia decurrens/jojoba/sunflower seed wax polyglyceryl-3 esters~1.9–2.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Acacia decurrens/jojoba/sunflower seed wax polyglyceryl-3 esters
Cetyl alcohol~1.7–2%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Glyceryl stearate~1.5–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
C12-15 alkyl benzoate~1.2–1.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Butyrospermum parkii butter~1–1.2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Ethoxydiglycol~0.65–0.95%
Irritant · medium
Irritation risk
Medium

Helps to improve the product consistency

More about Ethoxydiglycol
Squalane~0.6–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Ammonium acryloyldimethyltaurate/vp copolymer~0.5–0.75%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Peg-75 stearate~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Peg-75 stearate
Benzyl alcohol~0.35–0.65%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Panthenol~0.4–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Ectoin~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Tribehenin~0.35–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Ceteth-20~0.5–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteth-20
Steareth-20~0.4–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Butylene glycol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Phospholipids~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Hydrolyzed sericin~0.25–0.45%
Formula
Allantoin~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Olea europaea leaf extract~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract
Aloe barbadensis leaf juice~0.25–0.4%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialAnti-inflammatoryReduces irritationReduces rednessAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Stearyl glycyrrhetinate~0.2–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingReduces rednessAnti-inflammatory

A fatty acid derived from licorice. Works as an emollient and can help calm down inflammation

More about Stearyl glycyrrhetinate
Dehydroacetic acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Ceramide 2~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide 2
Peg-10 rapeseed sterol~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-10 rapeseed sterol
Elaeis guineensis oil~0.25–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Olea europaea fruit extract~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit extract
Tocotrienols~0.15–0.3%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols
Arginine~0.1–0.2%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Tocopherol~0.1–0.2%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Phosphatidylcholine~0.1–0.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Palmitoyl oligopeptide~0.15–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide
Ingredient list view

Water, Caprylic/capric triglyceride, Peg-8 dimethicone, Glycerin, Dimethicone, Acacia decurrens/jojoba/sunflower seed wax polyglyceryl-3 esters, Cetyl alcohol, Glyceryl stearate, C12-15 alkyl benzoate, Butyrospermum parkii butter, Ethoxydiglycol, Squalane, Ammonium acryloyldimethyltaurate/vp copolymer, Peg-75 stearate, Benzyl alcohol, Panthenol, Ectoin, Tribehenin, Ceteth-20, Steareth-20, Butylene glycol, Phospholipids, Hydrolyzed sericin, Allantoin, Xanthan gum, Olea europaea leaf extract, Aloe barbadensis leaf juice, Stearyl glycyrrhetinate, Dehydroacetic acid, Ceramide 2, Peg-10 rapeseed sterol, Elaeis guineensis oil, Olea europaea fruit extract, Tocotrienols, Arginine, Tocopherol, Phosphatidylcholine, Palmitoyl oligopeptide

Compare prices

Retailers ranked by price — lowest first.

Dermstore
$69.00
Buy
Perricone MD
$69.00
Buy
Amazon US
Price unavailable
Check

Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDHypoallergenic Nourishing MoisturizerYOUR PRODUCTM-61Hydraboost Moisturizer
Match—50%
Price$17.25$76.00+$58.75
Shared key ingredients—5 of 13
Key difference—Palmitoyl Tetrapeptide-7
Irritancy Low Low
Drying alcohol——
View product Shop
Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

"Perricone MD - Hypoallergenic Nourishing Moisturizer" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Panthenol, arginine, glycerin and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide 2, arginine, butyrospermum parkii butter, caprylic/capric triglyceride and dimethicone in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • As a plus, this moisturizer also contains ceramides (ceramide 2 0.25% - 0.45%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • We like that this moisturizer contains peptides (palmitoyl oligopeptide 0.15% - 0.30%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails for 69.00$ in the United States, for 139.77A$ in Australia, for 34.00£ in the United Kingdom and for 86.30CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
Perricone MD Hypoallergenic Nourishing Moisturizer
Perricone MDHypoallergenic Nourishing Moisturizer

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.