Perricone MD Hypoallergenic Firming Eye Cream

Perricone MD Hypoallergenic Firming Eye Cream

Efficacy83/100IrritancyLow
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Works for

3 of 3 advertised claims delivered

Moisturizing
22 ingredients credited for this claim
Strong support
What the product description says
“deeply nourishing yet non-greasy cream”
Source: Perricone MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: bis-diglyceryl polyacyladipate-2, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl octapeptide-3, acetyl tetrapeptide-5, palmitoyl oligopeptide, panthenol

Bis-diglyceryl polyacyladipate-2Key active· Emollient, OcclusiveEffect: HighHelps soften the upper layer of the skin and reduce water loss from its surface~2.5–3.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.75–1.1%
Acetyl octapeptide-3Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Acetyl tetrapeptide-5Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.5–7.9%
Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.35–0.6%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.35%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1–1.2%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~0.3–0.55%
Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.2–0.4%
Hydrogenated palm kernel glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~3.2–3.9%
Stearyl glycyrrhetinateKey activeEffect: MediumA fatty acid derived from licorice. Works as an emollient and can help calm down inflammation~0.2–0.35%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~2–2.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.9%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.2–1.4%
Olea europaea fruit extract· EmollientEffect: LowAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.2–0.4%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.7–2.1%
Hydrogenated palm glycerides· EmollientEffect: LowAn emollient that softens the skin~0.25–0.5%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.35%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%
Anti-aging
6 ingredients credited for this claim
Moderate support
What the product description says
“the best eye cream for fine lines”
Source: Perricone MD

This product contains acetyl octapeptide-3, acetyl tetrapeptide-5, palmitoyl oligopeptide, tocotrienols. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

TocotrienolsKey activeEffect: MediumA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.2–0.35%
Acetyl tetrapeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Acetyl octapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
ChrysinEffect: LowMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.1–0.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%
Evens skin tone
3 ingredients credited for this claim
Moderate support
What the product description says
“balance out any discolouration for a unified complexion”
Source: Mankind

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: chrysin, stearyl glycyrrhetinate.

ChrysinKey activeEffect: MediumMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.1–0.2%
Stearyl glycyrrhetinateKey activeEffect: MediumA fatty acid derived from licorice. Works as an emollient and can help calm down inflammation~0.2–0.35%
N-hydroxysuccinimideEffect: LowIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating~0.2–0.35%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - chrysin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

TocotrienolsKey activeEffect: HighA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.2–0.35%
ChrysinKey activeEffect: MediumMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.1–0.2%
Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.15–0.3%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Can it cause trouble?

Irritancy
11 flagged ingredients
Low risk
We flag 11 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
N-hydroxysuccinimideIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritatingHigh~0.2–0.35%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.5–7.9%est.
EthoxydiglycolHelps to improve the product consistencyMedium~0.5–0.75%est.
Peg-75 stearateHelps water and oil mix togetherMedium~0.45–0.65%est.
Steareth-20Helps oil and water mix togetherMedium~0.45–0.7%est.
Ceteth-20Helps water and oil mix togetherMedium~0.45–0.65%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.15–0.3%est.
Stearyl glycyrrhetinateA fatty acid derived from licorice. Works as an emollient and can help calm down inflammationMedium~0.2–0.35%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.2–0.4%est.
ChrysinMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skinMedium~0.1–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.5–1.9%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.5–7.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydrogenated palm kernel glycerides~3.2–3.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Hydrogenated palm kernel glycerides
Bis-diglyceryl polyacyladipate-2~2.5–3.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from its surface

More about Bis-diglyceryl polyacyladipate-2
Cetyl alcohol~2–2.5%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Glyceryl stearate~1.7–2.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cetearyl alcohol~1.5–1.9%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butylene glycol~1.2–1.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Squalane~1–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Dimethicone~0.75–1.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Ethoxydiglycol~0.5–0.75%
Irritant · medium
Irritation risk
Medium

Helps to improve the product consistency

More about Ethoxydiglycol
Phenoxyethanol~0.45–0.7%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Peg-75 stearate~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Peg-75 stearate
Ammonium acryloyldimethyltaurate/vp copolymer~0.35–0.65%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Panthenol~0.35–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Steareth-20~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Ectoin~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Ceteth-20~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteth-20
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hydrogenated palm glycerides~0.25–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides
Allantoin~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Olea europaea leaf extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract
Stearyl glycyrrhetinate~0.2–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingReduces rednessAnti-inflammatory

A fatty acid derived from licorice. Works as an emollient and can help calm down inflammation

More about Stearyl glycyrrhetinate
Sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Elaeis guineensis oil~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Olea europaea fruit extract~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit extract
Tocotrienols~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols
Tocopherol~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Phosphatidylcholine~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
N-hydroxysuccinimide~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Evens skin tone

Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating

More about N-hydroxysuccinimide
Acetyl tetrapeptide-5~0.15–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-5
Acetyl octapeptide-3~0.15–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl octapeptide-3
Hydrolyzed sericin~0.15–0.25%
Formula
Chrysin~0.1–0.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-oxidationAnti-aging

Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin

More about Chrysin
Palmitoyl oligopeptide~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide
Palmitoyl tetrapeptide-12~0.1–0.15%
Formula
Ingredient list view

Water, Caprylic/capric triglyceride, Glycerin, Hydrogenated palm kernel glycerides, Bis-diglyceryl polyacyladipate-2, Cetyl alcohol, Glyceryl stearate, Cetearyl alcohol, Butylene glycol, Squalane, Dimethicone, Ethoxydiglycol, Phenoxyethanol, Peg-75 stearate, Ammonium acryloyldimethyltaurate/vp copolymer, Panthenol, Steareth-20, Ectoin, Ceteth-20, Xanthan gum, Hydrogenated palm glycerides, Allantoin, Ethylhexylglycerin, Olea europaea leaf extract, Stearyl glycyrrhetinate, Sodium hyaluronate, Elaeis guineensis oil, Olea europaea fruit extract, Tocotrienols, Tocopherol, Phosphatidylcholine, N-hydroxysuccinimide, Acetyl tetrapeptide-5, Acetyl octapeptide-3, Hydrolyzed sericin, Chrysin, Palmitoyl oligopeptide, Palmitoyl tetrapeptide-12

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Amazon USPrice as of 10/15/2026 03:35 GMT
$75.00
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Perricone MD
$75.00
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Product summary

"Perricone MD - Hypoallergenic Firming Eye Cream" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Perricone MD - Hypoallergenic Firming Eye Cream ticks this box. Acetyl octapeptide-3, acetyl tetrapeptide-5, panthenol, glycerin and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, bis-diglyceryl polyacyladipate-2, caprylic/capric triglyceride and dimethicone) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (palmitoyl tripeptide-1 0.45% - 0.65%, palmitoyl tetrapeptide-7 0.45% - 0.65%, acetyl tetrapeptide-5 0.45% - 0.70% and acetyl octapeptide-3 0.40% - 0.60%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails for 100.99A$ in Australia, for 72.00$ in the United States and for 49.79£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 22 studies and safety reviews.

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Perricone MD Hypoallergenic Firming Eye Cream
Perricone MDHypoallergenic Firming Eye Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.