Perricone MD

Perricone MD High Potency Triple Retinol Renewal Eye Serum

Name: Perricone MD - High Potency Triple Retinol Renewal Eye Serum
Brand: Perricone MD

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Anti-aging

Retinol, Niacinamide + 8 more

Works well

What the product description says

“Diminishes the look of fine lines, wrinkles and crow's feet”

Source: Perricone MD

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: arginine/lysine polypeptide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.5%

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–1.9%

Arginine/lysine polypeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.3–0.55%

Thioctic acidEffect: Low~0.3–0.55%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.3–0.55%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.25–0.5%

Retinyl linoleateUnder-dosedAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.~0.3–0.5%

Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%

Evens skin tone

Retinol, Niacinamide + 3 more

Works well

What the product description says

“Visibly minimizes dark circles and discoloration for a more awakened look”

Source: Perricone MD

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.25–0.5%

Moisturizing

Side benefit the brand mentions · Niacinamide, Ceramide np + 27 more

Works well

What the product description says

“eye serum”

Source: Perricone MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, squalene.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: arginine/lysine polypeptide, ceramide np, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–1.9%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.45–0.65%

Arginine/lysine polypeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.9–3.6%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.4–2.9%

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.3–0.55%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.3–0.55%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.55%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.3–0.55%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.3–0.5%

Hydrolyzed glycosaminoglycansKey active· HumectantEffect: HighLong sugars that help attract water to the upper layer of the skin~0.3–0.5%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.3–0.55%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.3–0.6%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.3–0.5%

Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.3–0.6%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%

SqualeneKey active· Emollient, OcclusiveEffect: HighAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~0.15–0.25%

Beta-sitosterolKey active· EmollientEffect: HighA phytosterol that can support skin's barrier function and help the skin stay hydrated~0.15–0.3%

Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~4.1–5%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.9–2.3%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.65–1%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.6–0.85%

LysolecithinEffect: LowLecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin~0.3–0.55%

Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.5–0.75%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.6%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.35–0.65%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Anti-oxidation

Side benefit · Ubiquinone, Thioctic acid + 12 more

Works well

This product contains antioxidants (retinol, thioctic acid, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - squalene also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Thioctic acidKey activeEffect: High~0.3–0.55%

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.5%

SqualeneKey activeEffect: MediumAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~0.15–0.25%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.45–0.7%

Chlorella vulgaris extractEffect: LowA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.3–0.5%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.25–0.5%

Daucus carota sativa root extractEffect: LowCarrot extract. Might have anti-oxidant properties and be used to add orange color~0.15–0.25%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.3–0.5%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.55%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Exfoliation

Side benefit · Retinol, Allantoin + 1 more

Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Can it cause trouble?

Irritancy

1 strong irritant: Retinol

Medium risk

We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Retinyl linoleateAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.High~0.3–0.5%est.

RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.3–0.5%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.7–1.05%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.65–1%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.6–0.85%est.

Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.5–0.75%est.

PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.5–0.75%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.45–0.7%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.3–0.6%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.65%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.3–0.5%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.3–0.55%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.

Hydrogenated phosphatidylcholineHelps oil and water mix togetherMedium~0.3–0.55%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.25–0.5%est.

Laureth-23Helps oil and water mix togetherMedium~0.4–0.65%est.

1,2-hexanediolA preservativeMedium~0.3–0.5%est.

Trideceth-6 phosphateHelps oil and water mix togetherMedium~0.3–0.55%est.

Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.25–0.5%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.5%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.5%est.

Caprylhydroxamic acidA preservativeMedium~0.2–0.35%est.

Potassium sorbateA preservativeMedium~0.15–0.3%est.

Phytic acidAn alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmeticsMedium~0.15–0.3%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.3–0.5%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.3–0.6%est.

Laureth-23Helps oil and water mix together2/5~0.4–0.65%est.

SqualeneAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast2/5~0.15–0.25%est.

Alternatives

Cheaper, or higher on efficacy

Drunk Elephant Shaba Complex™ Eye Serum

Cheaper73% match

$45.50

Chemist Confessions Double Play Retinol Face & Eye Treatment

Cheaper67% match

$48.00

View all alternatives

User reviews

Would you recommend?

No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Propanediol~4.5–5.5%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Dicaprylyl ether~4.1–5%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether

Glycerin~2.9–3.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Squalane~2.4–2.9%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Butylene glycol~1.9–2.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Niacinamide~1.6–1.9%

Hero · Moisturizing

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Pvm/ma decadiene crosspolymer~1.4–1.7%

Formula

Irritation risk: Low

More about Pvm/ma decadiene crosspolymer

Phenoxyethanol~0.5–1%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Polysorbate 20~0.95–1.2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Hydroxyacetophenone~0.7–1.05%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Pentylene glycol~0.65–1%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Caprylyl glycol~0.6–0.85%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Cucumis sativus fruit extract~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract

Phosphatidylcholine~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine

Sodium hydroxide~0.45–0.7%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Caffeine~0.45–0.7%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Tetrasodium glutamate diacetate~0.45–0.65%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate

Ceramide np~0.45–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Allantoin~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Bisabolol~0.3–0.5%

Formula

Irritation risk: Low

Works for

Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Glycine soja oil~0.3–0.6%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Caprylic/capric triglyceride~0.35–0.65%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Tocopherol~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Diglucosyl gallic acid~0.3–0.55%

Formula

Irritation risk: Low

More about Diglucosyl gallic acid

Hydroxyphenyl propamidobenzoic acid~0.3–0.5%

Formula

Irritation risk: Low

Works for

Anti-inflammatory

Might help to reduce inflammation in skin, but solid research is lacking

More about Hydroxyphenyl propamidobenzoic acid

Chlorella vulgaris extract~0.3–0.5%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-inflammatoryAnti-oxidation

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Sodium hyaluronate crosspolymer~0.3–0.55%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Retinyl linoleate~0.3–0.5%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingAnti-oxidationEvens skin toneAnti-blemish

An ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.

More about Retinyl linoleate

Retinol~0.3–0.5%

Hero · Anti-aging, Evens skin toneIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-blemishMattifyingExfoliationAnti-oxidation

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol

Lecithin~0.3–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Sodium hyaluronate~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Tocopheryl acetate~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Hydrogenated phosphatidylcholine~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Hydrogenated phosphatidylcholine

Lysolecithin~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Lecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin

More about Lysolecithin

Glycyrrhiza glabra root extract~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Reduces rednessEvens skin toneAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Thioctic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-aging

More about Thioctic acid

Cetyl palmitate~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate

Laureth-23~0.4–0.65%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together

More about Laureth-23

Sodium acetylated hyaluronate~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Hyaluronic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Hydrolyzed glycosaminoglycans~0.3–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Hydrolyzed glycosaminoglycans

Hydrolyzed sodium hyaluronate~0.3–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Ubiquinone~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone

1,2-hexanediol~0.3–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Trideceth-6 phosphate~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Trideceth-6 phosphate

Ascorbyl palmitate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate

Lactic acid~0.25–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Citric acid~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Hydrolyzed hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Sodium benzoate~0.25–0.45%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Tetrapeptide-1~0.2–0.4%

Formula

Irritation risk: Low

More about Tetrapeptide-1

Caprylhydroxamic acid~0.2–0.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about Caprylhydroxamic acid

Potassium sorbate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Beta-carotene~0.15–0.3%

Formula

Irritation risk: Low

A colorant adding orange or bright yellow color

More about Beta-carotene

Daucus carota sativa root extract~0.15–0.25%

Formula

Irritation risk: Low

Works for

Anti-oxidation

Carrot extract. Might have anti-oxidant properties and be used to add orange color

More about Daucus carota sativa root extract

Phytic acid~0.15–0.3%

Irritant · medium

Irritation risk: Medium

An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics

More about Phytic acid

Beta-sitosterol~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A phytosterol that can support skin's barrier function and help the skin stay hydrated

More about Beta-sitosterol

Squalene~0.15–0.25%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

MoisturizingAnti-oxidation

An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast

More about Squalene

Arginine/lysine polypeptide~0.05–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Arginine/lysine polypeptide

Ingredient list view

Water, Propanediol, Dicaprylyl ether, Glycerin, Squalane, Butylene glycol, Niacinamide, Pvm/ma decadiene crosspolymer, Phenoxyethanol, Polysorbate 20, Hydroxyacetophenone, Pentylene glycol, Caprylyl glycol, Cucumis sativus fruit extract, Phosphatidylcholine, Sodium hydroxide, Caffeine, Tetrasodium glutamate diacetate, Ceramide np, Allantoin, Bisabolol, Glycine soja oil, Caprylic/capric triglyceride, Tocopherol, Diglucosyl gallic acid, Hydroxyphenyl propamidobenzoic acid, Chlorella vulgaris extract, Sodium hyaluronate crosspolymer, Retinyl linoleate, Retinol, Lecithin, Sodium hyaluronate, Tocopheryl acetate, Hydrogenated phosphatidylcholine, Lysolecithin, Glycyrrhiza glabra root extract, Thioctic acid, Cetyl palmitate, Laureth-23, Sodium acetylated hyaluronate, Hyaluronic acid, Hydrolyzed glycosaminoglycans, Hydrolyzed sodium hyaluronate, Ubiquinone, 1,2-hexanediol, Trideceth-6 phosphate, Ascorbyl palmitate, Lactic acid, Citric acid, Hydrolyzed hyaluronic acid, Sodium benzoate, Tetrapeptide-1, Caprylhydroxamic acid, Potassium sorbate, Beta-carotene, Daucus carota sativa root extract, Phytic acid, Beta-sitosterol, Squalene, Arginine/lysine polypeptide

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 11/9 03:11 GMT

$75.00

Buy

Perricone MD

$75.00

Buy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Perricone MDHigh Potency Triple Retinol Renewal Eye SerumYOUR PRODUCT	Drunk ElephantShaba Complex™ Eye Serum	Chemist ConfessionsDouble Play Retinol Face & Eye Treatment	innisfreeGreen Tea PDRN™ Bounce Booster Eye & Lip Serum
Match	—	73%	67%	67%
Price	$75.00	$45.50−$29.50	$48.00−$27.00	$24.88−$50.12
Shared key ingredients	—	11 of 25	8 of 25	6 of 25
Key difference	—	Dipeptide-2	Madecassoside	Acetyl Tetrapeptide-2
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

More alternatives: Heimish Marine Care Retinol Eye Serum SEPHORA COLLECTION Firming Eye Serum with Retinol and Caffeine

Cheaper alternatives? See how this stacks up against similar formulas.

We compare ingredient profiles across our catalog — pick the closest match for your budget.

Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 29 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
3
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
4
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
5
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
6
Profile of wound healing process induced by allantoinscielo.br
7
α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net
8
Vitamin E in dermatologyncbi.nlm.nih.gov
9
Vitamin E and Skin Healthlpi.oregonstate.edu
10
Metabolism of topical retinaldehyde and retinol by mouse skin in vivo: predominant formation of retinyl esters and identification of 14‐hydroxy‐4, 14‐retro‐retinolonlinelibrary.wiley.com
11
Auto-regulation of Retinoic Acid Biosynthesis through Regulation of Retinol Esterification in Human Keratinocytesjbc.org
12
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
13
Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
14
A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
15
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
16
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
17
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
18
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
19
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
20
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
21
Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
22
Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org
23
Cosmetic and dermatologic use of alpha hydroxy acidsonlinelibrary.wiley.com
24
Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasmancbi.nlm.nih.gov
25
Safety Assessment of Phytosterols as Used in Cosmeticscir-safety.org
26
The Ameliorative Effect of β-sitosterol on DNCB-induced Atopic Dermatitis in Micebslonline.org
27
Squalene and its potential clinical useseuropepmc.org
28
Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology mdpi.com
29
Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxidesonlinelibrary.wiley.com

Perricone MDHigh Potency Triple Retinol Renewal Eye Serum

Buy at Perricone MD$75.00 $75.00as of 11/9 03:11 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Perricone MD$75.00 $75.00as of 11/9 03:11 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.