
3 of 3 advertised claims delivered
“Reduces the appearance of wrinkles and creases.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-9.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
“Visibly corrects & prevents discoloration and dark spots.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
“This whipped, lightweight, moisturizing therapy visibly smooths the look of wrinkles, creases and crepey skin texture as it corrects the appearance of uneven skin tone and sun damage.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, mannitol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cyclopentasiloxane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-9, niacinamide
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
This product contains antioxidants (thioctic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).


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Filter by role to see what each ingredient is doing.
Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin
More about Titanium dioxideA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
More about CyclopentasiloxaneOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideHelps improve stability of sunscreen filters and boost their effectiveness
More about Ethylhexyl methoxycryleneUsed to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolA gelling agent that thickens the product consistency and leaves the skin with a velvety finish
More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerUsed to stabilize product formulations and individual ingredients (for example, sunscreens). Can be an allergen
More about Polyester-8Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
More about Tetrahexyldecyl ascorbateA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl tetrapeptide-9Used to stabilize the product formulation
More about Diethylhexyl syringylidenemalonateHelps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
More about Hydrogenated lecithinAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
More about BisabololUsed to create a thicker product consistency
More about Xanthan gumHelps oil and water mix together
More about Hydrogenated phosphatidylcholineHelps to attract water to the upper layer of the skin
More about MannitolA preservative. Can be used to mask unpleasant smell. Can be irritating
More about Benzyl alcoholHelps oil and water mix together and works as an emollient
More about Stearic acidImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
More about IsohexadecaneA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel
More about Polysilicone-11Helps oil and water mix together
More about Sorbitan isostearateA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideA preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIs used to add opaque (non-transparent) appearance to formulations. Can be used to coat other ingredients for even dispersion. This is a different ingredient compared to the ones used in antipersperants (aluminium chloride and aluminium chlorohydrate)
More about Aluminum hydroxideTitanium dioxide, Water, Dimethicone, Cyclopentasiloxane, Glycerin, Niacinamide, Ethylhexyl methoxycrylene, Pentylene glycol, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Polyester-8, Polyglyceryl-3 polydimethylsiloxyethyl dimethicone, Tetrahexyldecyl ascorbate, Thioctic acid, Acetyl tetrapeptide-9, Diethylhexyl syringylidenemalonate, Hydrogenated lecithin, Bisabolol, Xanthan gum, Hydrogenated phosphatidylcholine, Mannitol, Benzyl alcohol, Stearic acid, Isohexadecane, Polysilicone-11, Polysorbate 60, Sorbitan isostearate, Caprylic/capric triglyceride, Phenoxyethanol, Potassium sorbate, Sodium benzoate, Aluminum hydroxide
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Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDCold Plasma Plus Neck and ChestYOUR PRODUCT | MarudermHyaluronic Acid Moisturizer Face & Body Cream | CetaphilMoisturising Cream | La Roche-PosayLipikar Eczema Cream | |
|---|---|---|---|---|
| Match | — | 70% | 70% | 70% |
| Price | $82.50 | $21.99−$60.51 | $9.92−$72.58 | $12.79−$69.71 |
| Shared key ingredients | — | 4 of 12 | 3 of 12 | 3 of 12 |
| Key difference | — | Panthenol | Petrolatum | Mineral Oil |
| Irritancy | Low | Low | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Based on the ingredients included, "Perricone MD - Cold Plasma Plus Neck and Chest" works well for moisturizing the skin. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (glycerin and mannitol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (dimethicone, cyclopentasiloxane, isohexadecane and pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
The product retails from 86.20$ up to 89.00$ in the United States, for 121.27A$ in Australia, from 54.99£ up to 62.40£ in the United Kingdom and for 111.30CA$ in Canada.
For a detailed price comparison: click here.
Every concentration estimate and effectiveness label is anchored to one of these 10 studies and safety reviews.
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