Perricone MD Cold Plasma Plus Fragile Skin Therapy
Works for
4 of 4 advertised claims delivered
Evens skin tone2 ingredients credited for this claimStrong support
“Growth Factor Peptide: boosts firmer-looking skin and visibly corrects tone and texture, improving the appearance of thin, weakened skin”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: 3-o-ethyl ascorbic acid.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Anti-aging3 ingredients credited for this claimStrong support
“Helps smooth the look of crepey, rough skin as it visibly minimizes lines and wrinkles”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Exfoliation1 ingredient credited for this claimStrong support
“Retinol: dramatically reduces the look of fine lines, wrinkles over time by accelerating surface skin exfoliation”
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Moisturizing9 ingredients credited for this claimGood support
“Our proprietary liquid crystal delivery system allows for fast and deep penetration of key ingredients and hydration to nourish, strengthen and replenish.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
carnosine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, isopropyl myristate.
Anti-blemishNot advertised by the brand · 1 ingredient credited for this claimStrong support
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
Anti-oxidationNot advertised by the brand · 4 ingredients credited for this claimStrong support
This product contains antioxidants (carnosine, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - 3-o-ethyl ascorbic acid also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Can it cause trouble?
Irritancy1 strong irritant: RetinolMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Glycerin~4.5–6.8%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinIsopropyl myristate~3.7–5.5%
- Irritation risk
- Low
- Comedogenicity
- 3/5
An emollient that helps soften the skin. Could be comedogenic
More about Isopropyl myristateDistearyldimonium chloride~2.7–4%
- Irritation risk
- Low
Stearyl alcohol~2–3%
- Irritation risk
- Low
An emollient that helps soften the skin
More about Stearyl alcoholDimethicone~1.7–2.6%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeCetyl alcohol~1.4–2.1%
- Irritation risk
- Low
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
More about Cetyl alcohol3-o-ethyl ascorbic acid~1.2–1.8%
- Irritation risk
- High
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
More about 3-o-ethyl ascorbic acidStearic acid~1.1–1.7%
- Irritation risk
- Low
Helps oil and water mix together and works as an emollient
More about Stearic acidGlyceryl stearate~0.85–1.3%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateTocopheryl acetate~0.5–1.15%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateSodium metabisulfite~0.1–0.2%
Ethylhexylglycerin~0.35–0.85%
Retinol~0.35–0.8%
- Irritation risk
- High
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
More about RetinolCarnosine~0.2–0.75%
- Irritation risk
- Low
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
More about CarnosineHydrolyzed hyaluronic acid~0.15–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
More about Hydrolyzed hyaluronic acidXanthan gum~0.15–0.6%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumLecithin~0.15–0.65%
- Irritation risk
- Low
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
More about LecithinHeptapeptide-7~0.1–0.4%
- Irritation risk
- Low
Sodium chloride~0.1–0.4%
- Irritation risk
- Low
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
More about Sodium chlorideSodium hydroxide~0.1–0.3%
Polysorbate 20~0.05–0.3%
Propanediol~0.05–0.2%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolPhenoxyethanol~0.05–0.2%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIngredient list view
Water, Glycerin, Isopropyl myristate, Distearyldimonium chloride, Stearyl alcohol, Dimethicone, Cetyl alcohol, 3-o-ethyl ascorbic acid, Stearic acid, Glyceryl stearate, Tocopheryl acetate, Sodium metabisulfite, Ethylhexylglycerin, Retinol, Carnosine, Hydrolyzed hyaluronic acid, Xanthan gum, Lecithin, Heptapeptide-7, Sodium chloride, Sodium hydroxide, Polysorbate 20, Propanediol, Phenoxyethanol
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDCold Plasma Plus Fragile Skin TherapyYOUR PRODUCT | RoC SkincareDERM CORREXION Contour Cream | KopariUltra Renewal Retinol Body Cream | NaturiumVitamin C Super Eye Cream Plus | |
|---|---|---|---|---|
| Match | — | 77% | 76% | 75% |
| Price | $49.00 | — | $46.00−$3.00 | $20.00−$29.00 |
| Shared key ingredients | — | 4 of 7 | 3 of 7 | 4 of 7 |
| Key difference | — | Sodium Hyaluronate | Glycine Soja Oil | Vitamin C |
| Irritancy | Medium | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
- 1
- 2
- 3Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 4
- 5
- 6
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