PRODUCT REVIEW
Perricone MD Cold Plasma+ Advanced Serum Concentrate
Can it cause trouble?
Buy from Amazon US $119.20
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Price as of 2/11/2023 2:36 GMT.
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Product summary
What can the product work for?
Anti-aging
What does the product description say?
Target and improve fine lines, wrinkles, and loss of firmness, enlarged pores, discolouration, redness, uneven skin tone, uneven skin texture, and loss of radiance.
glycolic acid
0.45% -
0.65%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
palmitoyl tetrapeptide-7
0.55% -
0.85%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
copper tripeptide-1
0.35% -
0.6%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
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Evens skin tone
What does the product description say?
Target and improve fine lines, wrinkles, and loss of firmness, enlarged pores, discolouration, redness, uneven skin tone, uneven skin texture, and loss of radiance.
glycolic acid
0.45% -
0.65%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
tetrahexyldecyl ascorbate
1.2% -
1.4%
Irritation risk:
Concentration: Insufficient!
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
retinyl palmitate
0.25% -
0.4%
Irritation risk:
Concentration: Insufficient!
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
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Moisturizing
What does the product description say?
Utilising a proprietary liquid crystal delivery system for deep and effective penetration of key actives, the featherweight serum intensely nourishes and hydrates.
palmitoyl tetrapeptide-7
0.55% -
0.85%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
copper tripeptide-1
0.35% -
0.6%
Irritation risk:
Concentration: Effectiveness: HIGH
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
palmitoyl tripeptide-1
0.6% -
0.95%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Show more
Exfoliation
glycolic acid
0.45% -
0.65%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
copper gluconate
0.25% -
0.45%
Irritation risk:
Concentration: Insufficient!
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
retinyl palmitate
0.25% -
0.4%
Irritation risk:
Concentration: Insufficient!
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Show more
Anti-blemish
What does the product description say?
Pores.
glycolic acid
0.45% -
0.65%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
rosmarinus officinalis leaf extract
0.2% -
0.4%
Irritation risk:
Concentration: Insufficient!
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
retinyl palmitate
0.25% -
0.4%
Irritation risk:
Concentration: Insufficient!
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Show more
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone | |
| Anti-blemish |
Total Promises Fulfilled score:
87/100.
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Perricone MD
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 3
Potential irritants
glycolic acid
0.45% -
0.65%
Irritation risk:
Works for:
Anti-aging,
Exfoliation,
Evens skin tone,
Anti-blemish
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
hydrolyzed myrtus communis leaf extract
0.45% -
0.65%
Irritation risk:
Works for:
Anti-inflammatory,
Anti-oxidation
Show more
Comodogenic ingredients
isopropyl palmitate
5.4% -
6.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
cetearyl alcohol
2.5% -
3.1%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
User reviews (0)
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| Key ingredients |
| Common:
Other: | Common:
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Other:
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Other: | Common:
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| Irritancy | IRRITANCY
HIGH
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HIGH
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
HIGH
| IRRITANCY
LOW
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MEDIUM
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LOW
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Ingredients & concentrations
All ingredients
Key Actives
zinc gluconate
0.25% -
0.5%
Irritation risk:
Works for:
Moisturizing,
Exfoliation,
Anti-oxidation,
Anti-blemish,
Anti-aging,
Anti-inflammatory,
Evens skin tone
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
copper gluconate
0.25% -
0.45%
Irritation risk:
Works for:
Moisturizing,
Anti-blemish,
Exfoliation,
Anti-oxidation,
Anti-aging,
Evens skin tone
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Show more
Potential irritants
glycolic acid
0.45% -
0.65%
Irritation risk:
Works for:
Anti-aging,
Exfoliation,
Evens skin tone,
Anti-blemish
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
hydrolyzed myrtus communis leaf extract
0.45% -
0.65%
Irritation risk:
Works for:
Anti-inflammatory,
Anti-oxidation
Show more
Comodogenic ingredients
isopropyl palmitate
5.4% -
6.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
cetearyl alcohol
2.5% -
3.1%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
All ingredients
isopropyl palmitate
5.4% -
6.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
glycerin
4% -
4.9%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Show more
Ingredient list view
Water, Isopropyl palmitate, Glycerin, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Butylene glycol, Phosphatidylcholine, Tetrahexyldecyl ascorbate, Dimethyl mea, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Tyrosine, Echium plantagineum seed oil, Glycolic acid, Hydrolyzed myrtus communis leaf extract, Copper tripeptide-1, Helianthus annuus seed oil, Magnesium aspartate, Zinc gluconate, Copper gluconate, Ethylhexylglycerin, Rosmarinus officinalis leaf extract, Sodium hyaluronate, Retinyl palmitate, Disodium edta, Carbomer, Ceteareth-20, Hydrogenated vegetable glycerides, Dimethicone, Caprylyl glycol, Polysorbate 20, Phenoxyethanol, Sorbic acid, Potassium sorbate
Sources
- Final Report on the Safety Assessment of Isopropyl Isostearate
- Glycerol and the skin: holistic approach to its origin and functions
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review
- Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L.
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Dimethicone as a protective ingredient in topical medications