NEOGEN X SUR.MEDIC

NEOGEN X SUR.MEDIC Real Ferment Micro Essence Mini

Name: NEOGEN X SUR.MEDIC - Real Ferment Micro Essence Mini
Brand: NEOGEN X SUR.MEDIC

Efficacy62/100IrritancyMedium

See all ingredients

Works for

Moisturizing

Bifida ferment lysate, Saccharomyces ferment filtrate + 28 more

Works

What the product description says

“Neogen Real Ferment Micro Essence is formulated with more than 93% micro bio ferment complex to brighten your skin tone while providing a deep hydration.”

Source: Lila Beauty

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylyl glycol.

Bifida ferment lysateKey activeEffect: HighConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~23–34%

Saccharomyces ferment filtrateKey active· HumectantEffect: HighA product of yeast fermentation. Helps attract water to the upper layer of the skin~5.7–8.6%

Rice ferment filtrateKey activeEffect: HighHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~3.6–5.4%

Aspergillus fermentKey activeEffect: MediumAn extract from fungus (mold) that typically appears on rice. It can help attract water to the upper layer of the skin, might help neutralize free radicals and possibly somewhat reduce hyperpigmentation~2.8–4.2%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.1–3.2%

Methyl gluceth-20Key active· HumectantEffect: MediumHelps attract water to the upper layer of the skin and soften it~1.3–2%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.9–1.35%

TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.45–1.1%

LactobacillusKey activeEffect: HighA non-living ingredient made by fermentation with the bacteria Lactobacillus. It can help attract water to the upper layer of the skin and might help reduce inflammation~0.45–1.05%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.3–0.75%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.3–0.75%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.75%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.3–0.7%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.3–0.7%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.75%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.75%

LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.8%

TyrosineKey activeEffect: High~0.2–0.8%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.75%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.55%

ProlineKey activeEffect: Medium~0.15–0.7%

HistidineKey active· HumectantEffect: High~0.1–0.4%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.1–0.45%

CysteineKey activeEffect: HighMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.05–0.25%

Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.8–1.2%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.45–1.1%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.35–0.8%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.75%

NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.3–0.75%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.75%

Evens skin tone

Bifida ferment lysate, Aspergillus ferment + 4 more

Not delivered

What the product description says

“Neogen Real Ferment Micro Essence is formulated with more than 93% micro bio ferment complex to brighten your skin tone while providing a deep hydration.”

Source: Lila Beauty

This product contains ingredients (alanine, bifida ferment lysate, cysteine) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.

Bifida ferment lysateEffect: LowConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~23–34%

Aspergillus fermentEffect: LowAn extract from fungus (mold) that typically appears on rice. It can help attract water to the upper layer of the skin, might help neutralize free radicals and possibly somewhat reduce hyperpigmentation~2.8–4.2%

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.75%

CysteineEffect: LowMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.05–0.25%

Anti-aging

Side benefit · Adenosine, Aspartic acid + 5 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aspartic acid, lysine, serine, threonine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.75%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.3–0.7%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.75%

LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.8%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.55%

Anti-oxidation

Side benefit · Bifida ferment lysate, Camellia sinensis leaf extract + 4 more

May help

This product contains antioxidants (bifida ferment lysate, camellia sinensis leaf extract, cysteine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Bifida ferment lysateKey activeEffect: MediumConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~23–34%

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.8–1.2%

CysteineKey activeEffect: MediumMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.05–0.25%

Rice ferment filtrateEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~3.6–5.4%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.75%

Can it cause trouble?

Irritancy

7 flagged ingredients

Medium risk

We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Coptis japonica extract—High~0.3–0.75%est.

EthylhexylglycerinA preservativeMedium~0.5–1.2%est.

Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~0.45–1%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.45–1.1%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.45–1.1%est.

1,2-hexanediolA preservativeMedium~0.35–0.85%est.

Hydroxypropyl methylcelluloseUsed to create a thicker product consistency and stabilize the formulationMedium~0.35–0.85%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

Cheaper, or higher on efficacy

MISSHA Time Revolution The First Treatment Essence Intensive Moist

Higher efficacy · 100/10084% match

$26.80

numbuzin No.3 Bifida Bakuchiol 50 Zero Pore Milky Toner

Higher efficacy · 100/10080% match

$14.70

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Ingredients

Filter by role to see what each ingredient is doing.

Bifida ferment lysate~23–34%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate

Saccharomyces ferment filtrate~5.7–8.6%

Key active

Irritation risk: Low

Works for

Moisturizing

A product of yeast fermentation. Helps attract water to the upper layer of the skin

More about Saccharomyces ferment filtrate

Betula alba juice~4.6–6.9%

Formula

Irritation risk: Low

More about Betula alba juice

Rice ferment filtrate~3.6–5.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin. Might have some anti-oxidant properties

More about Rice ferment filtrate

Aspergillus ferment~2.8–4.2%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

An extract from fungus (mold) that typically appears on rice. It can help attract water to the upper layer of the skin, might help neutralize free radicals and possibly somewhat reduce hyperpigmentation

More about Aspergillus ferment

Glycerin~2.1–3.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Dipropylene glycol~1.5–2.3%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Methyl gluceth-20~1.3–2%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and soften it

More about Methyl gluceth-20

Water~1.1–1.7%

Formula

Irritation risk: Low

Plain old water

More about Water

Betaine~0.9–1.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Camellia sinensis leaf extract~0.8–1.2%

Key active

Irritation risk: Low

Works for

AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Ethylhexylglycerin~0.5–1.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Trehalose~0.45–1.1%

Key active

Irritation risk: Low

Works for

Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose

Lactobacillus~0.45–1.05%

Key active

Irritation risk: Low

Works for

Moisturizing

A non-living ingredient made by fermentation with the bacteria Lactobacillus. It can help attract water to the upper layer of the skin and might help reduce inflammation

More about Lactobacillus

Peg-60 hydrogenated castor oil~0.45–1%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil

Caprylyl glycol~0.45–1.1%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Trideceth-10~0.55–1.3%

Formula

Irritation risk: Low

Works for

Cleansing

More about Trideceth-10

Acrylates/c10-30 alkyl acrylate crosspolymer~0.45–1.1%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Tromethamine~0.4–0.9%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

1,2-hexanediol~0.35–0.85%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Tropolone~0.35–0.8%

Formula

Irritation risk: Low

More about Tropolone

Allantoin~0.2–0.75%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Butylene glycol~0.3–0.75%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Coptis japonica extract~0.3–0.75%

Irritant · high

Irritation risk: High

More about Coptis japonica extract

Arginine~0.3–0.7%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Hydroxypropyl methylcellulose~0.35–0.85%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Hydroxypropyl methylcellulose

Hydrogenated lecithin~0.35–0.8%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Calcium carbonate~0.45–1.05%

Formula

Irritation risk: Low

Helps improve the product appearance

More about Calcium carbonate

Sodium hyaluronate~0.3–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Adenosine~0.3–0.75%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Niacinamide~0.3–0.75%

Under-dosed

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Dextrin~0.35–0.8%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Glycine~0.3–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Serine~0.3–0.75%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Glutamic acid~0.3–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Aspartic acid~0.3–0.7%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Leucine~0.2–0.8%

Formula

Irritation risk: Low

More about Leucine

Alanine~0.2–0.75%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Lysine~0.2–0.8%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine

Tyrosine~0.2–0.8%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Phenylalanine~0.2–0.8%

Formula

Irritation risk: Low

More about Phenylalanine

Proline~0.15–0.7%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Threonine~0.15–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Valine~0.1–0.5%

Formula

Irritation risk: Low

More about Valine

Isoleucine~0.1–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Phenoxyethanol~0.1–0.45%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Histidine~0.1–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Methionine~0.1–0.35%

Formula

Irritation risk: Low

More about Methionine

Cysteine~0.05–0.25%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Might help neutralize free radicals in skin and might be helpful against hyperpigmentation

More about Cysteine

Ingredient list view

Bifida ferment lysate, Saccharomyces ferment filtrate, Betula alba juice, Rice ferment filtrate, Aspergillus ferment, Glycerin, Dipropylene glycol, Methyl gluceth-20, Water, Betaine, Camellia sinensis leaf extract, Ethylhexylglycerin, Trehalose, Lactobacillus, Peg-60 hydrogenated castor oil, Caprylyl glycol, Trideceth-10, Acrylates/c10-30 alkyl acrylate crosspolymer, Tromethamine, 1,2-hexanediol, Tropolone, Allantoin, Butylene glycol, Coptis japonica extract, Arginine, Hydroxypropyl methylcellulose, Hydrogenated lecithin, Calcium carbonate, Sodium hyaluronate, Adenosine, Niacinamide, Dextrin, Glycine, Serine, Glutamic acid, Aspartic acid, Leucine, Alanine, Lysine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Phenoxyethanol, Histidine, Methionine, Cysteine

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	NEOGEN X SUR.MEDICReal Ferment Micro Essence MiniYOUR PRODUCT	MISSHATime Revolution The First Treatment Essence Intensive Moist	numbuzinNo.3 Bifida Bakuchiol 50 Zero Pore Milky Toner	Mary&MayVitamin B5 + Bifida Toner
Match	—	84%	80%	78%
Price	—	$26.80	$14.70	$14.39
Shared key ingredients	—	5 of 24	7 of 24	6 of 24
Key difference	—	Dimethicone	Pitera	Panthenol
Irritancy	Medium	Low	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Neogen - Real Ferment Micro Essence Mini" is effective for: Anti-aging

This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

Adenosine 0.30% - 0.75%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Humectants (histidine 0.10% - 0.40%, alanine 0.20% - 0.75%, aspartic acid 0.30% - 0.70%, glutamic acid 0.30% - 0.75%, glycine 0.30% - 0.75%, sodium hyaluronate 0.30% - 0.75%, arginine 0.30% - 0.70%, trehalose 0.50% - 1.20%, glycerin 2.10% - 3.20% and saccharomyces ferment filtrate 5.70% - 8.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 6.00A$ up to 10.50A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 22 studies and safety reviews.

1
Bifidobacterium longumlysate, a new ingredient forreactive skinonlinelibrary.wiley.com
2
Use of Probiotics for Dermal Applicationsresearchgate.net
3
Brewer's rice: A potential substrate for cosmeceutical bio-ingredient production by solid state fermentation using Aspergillus oryzaeresearchgate.net
4
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
5
Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
6
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
7
Profile of wound healing process induced by allantoinscielo.br
8
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
9
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
10
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
11
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
12
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
13
Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiencyjamanetwork.com
14
Functional glycine receptor in cultured human keratinocytesonlinelibrary.wiley.com
15
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
16
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
17
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
18
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
19
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
20
Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseasespatents.google.com
21
Safety Assessment of α-Amino Acids as Used in Cosmeticsciteseerx.ist.psu.edu
22
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NEOGEN X SUR.MEDICReal Ferment Micro Essence Mini

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