NEOGEN X SUR.MEDIC

NEOGEN X SUR.MEDIC V.Biome Soothing Cream

Name: NEOGEN X SUR.MEDIC - V.Biome Soothing Cream
Brand: NEOGEN X SUR.MEDIC

Efficacy100/100IrritancyHigh

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Works for

4 of 4 advertised claims delivered

Anti-aging

Niacinamide, Adenosine + 8 more

Strong evidence

What the product description says

“- Mini Globe the helps to reduce wrinkles around the eyes, mouth and jawline.”

Source: Neogenlab

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: folic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.3%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.35%

Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.05–0.25%

Lactococcus ferment lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~0.05–0.3%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.05–0.2%

Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.05–0.25%

Ascorbyl tetraisopalmitateUnder-dosedEffect: MediumA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.05–0.25%

Magnesium ascorbyl phosphateEffect: Low, below effective doseA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~0.05–0.2%

Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.05–0.25%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.25%

Evens skin tone

Niacinamide, Magnesium ascorbyl phosphate + 2 more

Strong evidence

What the product description says

“▶ Improvement of alleviation of blemishes/dark spots on the face (when used 5 times).”

Source: Neogenlab

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Moisturizing

Niacinamide, Panthenol + 23 more

Strong evidence

What the product description says

“Moisture improvement up to 10 layers of stratum corneum on both forearms (when used once).”

Source: Neogenlab

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, chondrus crispus extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol

Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.05–0.3%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.05–0.15%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.05–0.2%

Lactococcus ferment lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~0.05–0.3%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.3%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~3.2–4.8%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.05–0.2%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.05–0.2%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.05–0.2%

TriethylhexanoinKey activeEffect: HighHelps soften the upper layer of the skin~1–1.6%

Calcium pantothenateKey activeEffect: HighHelps support skin barrier function improving skin hydration and reducing sensitivity~0.05–0.25%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1–1.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.1–6.1%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.05–0.2%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.05–0.25%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.35%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.05–0.25%

Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~1.3–2%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.05–0.25%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.05–0.25%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.05–0.2%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.15–0.6%

Linoleic acidUnder-dosedEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.1–0.35%

Ascorbyl tetraisopalmitateEffect: Low, below effective doseA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.05–0.25%

Anti-blemish

Niacinamide, Sodium ascorbyl phosphate + 1 more

Strong evidence

What the product description says

“▶ Improvement of alleviation of blemishes/dark spots on the face (when used 5 times).”

Source: Neogenlab

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Sodium ascorbyl phosphateUnder-dosedEffect: HighA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.05–0.25%

Linoleic acidUnder-dosedEffect: MediumAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.1–0.35%

Anti-oxidation

Not advertised by the brand · Pyridoxine, Pyridoxine hcl + 10 more

Moderate evidence

This product contains antioxidants (pyridoxine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

PyridoxineKey activeEffect: MediumMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating~0.05–0.25%

Pyridoxine hclEffect: LowMight help neutralize free radicals in skin~0.05–0.2%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.35%

Malva sylvestris flower extractEffect: LowUsed as a fragrance~0.5–1.15%

Ascorbyl tetraisopalmitateUnder-dosedEffect: HighA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.05–0.25%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.25%

Sodium ascorbyl phosphateUnder-dosedEffect: MediumA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.05–0.25%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.05–0.25%

Anthemis nobilis flower oilEffect: Low, below effective doseAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin~0.1–0.3%

Can it cause trouble?

Irritancy

3 strong irritants: Malva sylvestris flower extract, Citrus aurantium amara flower extract + 1 more — patch-test recommended

High risk

We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Malva sylvestris flower extractUsed as a fragranceHigh~0.5–1.15%est.

Anthemis nobilis flower oilAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skinHigh~0.1–0.3%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.05–0.25%est.

Citrus aurantium amara flower extractUsed as a fragrance for its citrus smell. Can be irritatingHigh~0.05–0.2%est.

Gardenia florida fruit extractUsed as a fragrance. Can be irritating.High~0.05–0.2%est.

PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.05–0.25%est.

1,2-hexanediolA preservativeMedium~0.95–1.45%est.

TriethylhexanoinHelps soften the upper layer of the skinMedium~1–1.6%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1–1.5%est.

Polyglyceryl-2 stearateHelps water and oil mix togetherMedium~0.2–0.75%est.

EthylhexylglycerinA preservativeMedium~0.1–0.4%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.05–0.25%est.

Magnesium ascorbyl phosphateA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very highMedium~0.05–0.2%est.

Ascorbyl tetraisopalmitateA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)Medium~0.05–0.25%est.

Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.05–0.25%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.05–0.25%est.

Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.05–0.25%est.

Pyridoxine hclMight help neutralize free radicals in skinMedium~0.05–0.2%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.05–0.2%est.

Thiamine hclCan help attract water to the upper layer of the skin. Is studied as a mosquito repellentMedium~0.05–0.2%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.05–0.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.1–6.1%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Panthenol~3.2–4.8%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Propanediol~2.5–3.7%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

1,2-hexanediol~0.95–1.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Niacinamide~1.6–2.3%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Coco-caprylate/caprate~1.3–2%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate

Triethylhexanoin~1–1.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Triethylhexanoin

Caprylic/capric triglyceride~1–1.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Malva sylvestris flower extract~0.5–1.15%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Used as a fragrance

More about Malva sylvestris flower extract

Ammonium acryloyldimethyltaurate/vp copolymer~0.35–0.85%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Polyglyceryl-2 stearate~0.2–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-2 stearate

Glyceryl stearate~0.15–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Stearyl alcohol~0.15–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol

Hydrogenated lecithin~0.1–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Ethylhexylglycerin~0.1–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Anthemis nobilis flower oil~0.1–0.3%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-oxidation

An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin

More about Anthemis nobilis flower oil

Adenosine~0.1–0.35%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Thuja occidentalis leaf oil~0.1–0.3%

Formula

Irritation risk: Low

More about Thuja occidentalis leaf oil

Lactococcus ferment lysate~0.05–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-agingAnti-inflammatory

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin

More about Lactococcus ferment lysate

Ascorbic acid~0.05–0.25%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Citrus aurantium amara flower extract~0.05–0.2%

Irritant · high

Irritation risk: High

Used as a fragrance for its citrus smell. Can be irritating

More about Citrus aurantium amara flower extract

Collagen extract~0.05–0.15%

Formula

Irritation risk: Low

More about Collagen extract

Cyanocobalamin~0.05–0.15%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Xanthan gum~0.05–0.2%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Caprylyl glycol~0.05–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Maltodextrin~0.05–0.2%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Magnesium ascorbyl phosphate~0.05–0.2%

Irritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-agingAnti-oxidation

A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high

More about Magnesium ascorbyl phosphate

Butylene glycol~0.05–0.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Ascorbyl tetraisopalmitate~0.05–0.25%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-agingEvens skin toneMoisturizing

A vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)

More about Ascorbyl tetraisopalmitate

Glucose~0.05–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Sodium starch octenylsuccinate~0.05–0.25%

Formula

Irritation risk: Low

More about Sodium starch octenylsuccinate

Sodium hyaluronate~0.05–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Calcium pantothenate~0.05–0.25%

Key active

Irritation risk: Low

Works for

MoisturizingReduces irritation

Helps support skin barrier function improving skin hydration and reducing sensitivity

More about Calcium pantothenate

Chondrus crispus extract~0.05–0.3%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract

Sodium ascorbyl phosphate~0.05–0.25%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate

Polyglyceryl-10 diisostearate~0.05–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-10 diisostearate

Gardenia florida fruit extract~0.05–0.2%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating.

More about Gardenia florida fruit extract

Sodium polyphosphate~0.05–0.2%

Formula

Irritation risk: Low

More about Sodium polyphosphate

Tocopheryl acetate~0.05–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Polyglyceryl-10 laurate~0.05–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate

Pyridoxine hcl~0.05–0.2%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl

Hydroxypropyltrimonium hyaluronate~0.05–0.25%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Sodium ascorbate~0.05–0.25%

Formula

Irritation risk: Low

More about Sodium ascorbate

Menadione~0.05–0.25%

Formula

Irritation risk: Low

More about Menadione

Tricalcium phosphate~0.1–0.4%

Formula

Irritation risk: Low

More about Tricalcium phosphate

Silica~0.1–0.45%

Formula

Irritation risk: Low

Used to absorb oil and can temporarily mattify skin

More about Silica

Hydrolyzed hyaluronic acid~0.05–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Sodium acetylated hyaluronate~0.05–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Hyaluronic acid~0.05–0.2%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Sodium hyaluronate crosspolymer~0.05–0.2%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Hydrolyzed sodium hyaluronate~0.05–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Biotin~0.05–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Potassium hyaluronate~0.1–0.3%

Formula

Irritation risk: Low

More about Potassium hyaluronate

Pyridoxine~0.05–0.25%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine

Folic acid~0.05–0.25%

Key active

Irritation risk: Low

Works for

Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid

Tocopherol~0.05–0.25%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Riboflavin~0.05–0.25%

Formula

Irritation risk: Low

More about Riboflavin

Thiamine hcl~0.05–0.2%

Irritant · medium

Irritation risk: Medium

Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent

More about Thiamine hcl

Linoleic acid~0.1–0.35%

Under-dosed

Irritation risk: Low

Works for

MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid

Beta-carotene~0.01–0.1%

Formula

Irritation risk: Low

A colorant adding orange or bright yellow color

More about Beta-carotene

Ingredient list view

Water, Glycerin, Panthenol, Propanediol, 1,2-hexanediol, Niacinamide, Coco-caprylate/caprate, Triethylhexanoin, Caprylic/capric triglyceride, Malva sylvestris flower extract, Ammonium acryloyldimethyltaurate/vp copolymer, Polyglyceryl-2 stearate, Glyceryl stearate, Stearyl alcohol, Hydrogenated lecithin, Ethylhexylglycerin, Anthemis nobilis flower oil, Adenosine, Thuja occidentalis leaf oil, Lactococcus ferment lysate, Ascorbic acid, Citrus aurantium amara flower extract, Collagen extract, Cyanocobalamin, Xanthan gum, Caprylyl glycol, Maltodextrin, Magnesium ascorbyl phosphate, Butylene glycol, Ascorbyl tetraisopalmitate, Glucose, Sodium starch octenylsuccinate, Sodium hyaluronate, Calcium pantothenate, Chondrus crispus extract, Sodium ascorbyl phosphate, Polyglyceryl-10 diisostearate, Gardenia florida fruit extract, Sodium polyphosphate, Tocopheryl acetate, Polyglyceryl-10 laurate, Pyridoxine hcl, Hydroxypropyltrimonium hyaluronate, Sodium ascorbate, Menadione, Tricalcium phosphate, Silica, Hydrolyzed hyaluronic acid, Sodium acetylated hyaluronate, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Biotin, Potassium hyaluronate, Pyridoxine, Folic acid, Tocopherol, Riboflavin, Thiamine hcl, Linoleic acid, Beta-carotene

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	NEOGEN X SUR.MEDICV.Biome Soothing CreamYOUR PRODUCT	hwarang'Bellflower Moisturizing Barrier Cream	Milk TouchGreen Apple Collagen Cream	SkinfoodBlue Chamomile Hyaluronic Cream 70ml
Match	—	89%	87%	87%
Price	$30.40	$16.83−$13.57	$27.40−$3.00	$14.72−$15.68
Shared key ingredients	—	12 of 19	10 of 19	10 of 19
Key difference	—	Ceramide Np	Dipotassium Glycyrrhizate	Glyceryl Acrylate/Acrylic Acid Copolymer
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredient list, "Neogen - V. Biome Soothing Cream" can work well for skin moisturization. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (panthenol, glycerin, hydrolyzed hyaluronic acid, sodium acetylated hyaluronate and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Caprylic/capric triglyceride, coco-caprylate/caprate, caprylyl glycol and glyceryl stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

We particularly like that there is a good concentration of Niacinamide (1.60% - 2.30%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.05% - 0.25%) it cannot have a noticeable benefit for the skin.
Adenosine 0.10% - 0.35%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
An effective concentration of Panthenol (pro-vitamin B5) - about 3.20% - 4.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, sodium ascorbyl phosphate, linoleic acid, ascorbyl tetraisopalmitate and vitamin c

Irritation risk

We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.